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3-Cyclohexyl-3-phenylazetidine

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Identification
Molecular formula
C16H23N
CAS number
56296-81-0
IUPAC name
3-cyclohexyl-3-phenyl-azetidine
State
State

At room temperature, 3-cyclohexyl-3-phenylazetidine is typically found in a liquid or semi-solid state, with slight variance based on environmental conditions.

Melting point (Celsius)
52.50
Melting point (Kelvin)
325.65
Boiling point (Celsius)
286.30
Boiling point (Kelvin)
559.45
General information
Molecular weight
229.36g/mol
Molar mass
229.3610g/mol
Density
1.0490g/cm3
Appearence

3-Cyclohexyl-3-phenylazetidine is typically a colorless to pale yellow liquid. It can also appear in crystalline solid form depending on temperature and purity. The liquid has an oily texture.

Comment on solubility

Solubility of 3-cyclohexyl-3-phenyl-azetidine

The compound 3-cyclohexyl-3-phenyl-azetidine is an intriguing molecule when it comes to its solubility characteristics. Understanding the solubility of organic compounds like this azetidine derivative involves several factors:

  • Polarity: The solubility of organic compounds is often influenced by their polarity. 3-cyclohexyl-3-phenyl-azetidine has a relatively non-polar structure due to the hydrocarbon rings, which may result in limited solubility in polar solvents.
  • Solvent Compatibility: Generally, organic compounds such as this azetidine are more soluble in non-polar solvents. Hence, they might show reasonable solubility in solvents like hexane or toluene, while exhibiting poor solubility in water.
  • Molecular Interactions: The solubility is also affected by molecular interactions. The presence of functional groups can facilitate interactions with solvents, but in this case, the non-polar characteristics could hinder such interactions.

In conclusion, it can be said that the solubility of 3-cyclohexyl-3-phenyl-azetidine is expected to be:

  1. Good in non-polar solvents (e.g., hexane, benzene)
  2. Poor in polar solvents (e.g., water, methanol)

As such, one would need to carefully choose the appropriate solvent for applications involving this compound to ensure satisfactory solvation and performance.

Interesting facts

Interesting Facts about 3-Cyclohexyl-3-phenyl-azetidine

3-Cyclohexyl-3-phenyl-azetidine is a unique organic compound that belongs to the family of azetidines, a type of saturated four-membered ring containing nitrogen. Here are some fascinating insights into this compound:

  • Structural Diversity: The presence of both cyclohexyl and phenyl substituents contributes to the compound's structural variety, allowing it to exhibit interesting chemical reactivity and potential applications in medicinal chemistry.
  • Potential in Drug Development: Compounds like 3-cyclohexyl-3-phenyl-azetidine are of great interest in the field of pharmaceuticals, where they can serve as scaffolds for the design of new drugs targeting various diseases. Azetidine derivatives often show promise due to their ability to mimic biologically relevant frameworks.
  • Research Implications: Scientists have been exploring azetidine derivatives for their potential neuroprotective and anti-inflammatory properties, making such compounds a focal point in current medicinal studies.
  • Synthesis Challenges: The synthesis of azetidines often presents challenges due to steric hindrance, especially with larger substituents like cyclohexyl and phenyl groups. Researchers continuously seek innovative synthetic pathways to overcome these obstacles.
  • Stability: While the four-membered ring structure is generally strained, the substituents in 3-cyclohexyl-3-phenyl-azetidine help stabilize the ring, making it a subject of interest in understanding ring strain and stability in organic chemistry.

In summary, 3-cyclohexyl-3-phenyl-azetidine represents a fascinating intersection of organic chemistry and medicinal research, highlighting the potential for this compound class in the development of innovative therapeutic agents.

Synonyms
3-Cyclohexyl-3-phenylazetidine
AZETIDINE, 3-CYCLOHEXYL-3-PHENYL-
L 2027
BRN 0170841
DTXSID30222490
4-20-00-03315 (Beilstein Handbook Reference)
DTXCID30144981
7215-24-9