Skip to main content

Metformin Hydrochloride

ADVERTISEMENT
Identification
Molecular formula
C4H12ClN5
CAS number
1115-70-4
IUPAC name
3-(diaminomethylene)-1,1-dimethyl-guanidine;hydrochloride
State
State

At room temperature, Metformin Hydrochloride is typically in a solid state as a crystalline powder.

Melting point (Celsius)
223.00
Melting point (Kelvin)
496.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
165.62g/mol
Molar mass
165.6250g/mol
Density
1.5000g/cm3
Appearence

Metformin Hydrochloride is a white to off-white crystalline powder. It is odorless and hygroscopic.

Comment on solubility

Solubility of 3-(diaminomethylene)-1,1-dimethyl-guanidine; hydrochloride

The solubility of 3-(diaminomethylene)-1,1-dimethyl-guanidine; hydrochloride in various solvents can be quite significant due to its ionic nature. This compound is a hydrochloride salt, which typically enhances its solubility in water. Here are some key points regarding its solubility:

  • Water Solubility: It is generally highly soluble in water, making it suitable for various biological and chemical applications.
  • Organic Solvents: This compound may have limited solubility in organic solvents, as its structure favors interactions with polar solvents.
  • Temperature Dependence: The solubility may increase with temperature, which is a common trait of many salts.
  • pH Influence: The solubility can be influenced by the pH of the solution; in acidic conditions, it remains in its ionic form, enhancing solubility.

In conclusion, the solubility of 3-(diaminomethylene)-1,1-dimethyl-guanidine; hydrochloride is favorable in aqueous environments, which is essential for its functionality in various applications.

Interesting facts

Interesting Facts about 3-(Diaminomethylene)-1,1-dimethyl-guanidine Hydrochloride

3-(Diaminomethylene)-1,1-dimethyl-guanidine hydrochloride, often referred to in the scientific community as a versatile compound, plays a pivotal role in various chemical applications. Here are some fascinating insights about this compound:

  • Biological Significance: This compound is notable for its role in biological systems, often acting as a substrate in enzymatic reactions. Its unique structure allows for interactions with a wide range of biological molecules.
  • Protonation Behavior: The guanidine group in this compound significantly influences its protonation state, making it an interesting subject for studies in acid-base chemistry. This property enhances its solubility and reactivity in different environments.
  • Research Applications: It has been frequently utilized in pharmaceutical research for developing potential therapeutic agents, particularly in targeting metabolic pathways due to its nitrogen-rich functional groups.
  • Biomolecular Interactions: Researchers are intrigued by its ability to form hydrogen bonds and interact with DNA and proteins, leading to varied biological activity, including antifungal properties.
  • Complex Formation: The potential of this compound to form complexes with metals has garnered attention in materials science, contributing to the development of new catalytic materials.

The study of 3-(diaminomethylene)-1,1-dimethyl-guanidine hydrochloride exemplifies the intersection of organic chemistry and biochemistry. It serves as a reminder of the intricate connections within the molecular world and encourages further exploration of its multifaceted applications. As scientists delve deeper, they continue to uncover the compound's secrets and its significance in both research and industry.

Synonyms
Metformin hydrochloride
1115-70-4
Metformin HCL
1,1-Dimethylbiguanide hydrochloride
Diabefagos
Riomet
Benofomin
Fortamet
Siamformet
Walaphage
Meguan
Denkaform
Diaberit
Diabesin
Diabetex
Diabetmin
Diaformin
Diaphage
Diformin
Glibomet
Glucofago
Glucoform
Glucoliz
Glucomet
Glucomine
Gluconil
Gluformin
Glupermin
Glyciphage
Glycoran
Glyformin
Meglucon
Mescorit
Metforal
Metolmin
Biocos
Dextin
Diamin
Fornidd
Geamet
Metbay
Metomin
N1,N1-Dimethylbiguanide hydrochloride
Risidon
Thiabet
Dabex
Islotin retard
Diformin Retard
Glucophage-Mite
Apo-Metformin
Metformin monohydrochloride
Novo-Metformin
Glucophage Forte
Glucophage Retard
Dimethylbiguanide hydrochloride
DMGG hydrochloride
Glucophage 850
Apophage
Cidophage
Glucaminol
Neodipa
Metiguanide monohydrochloride
N,N-Dimethylbiguanide hydrochloride
Haurymellin hydrochloride
Metformin HCl ER
Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride
N,N-dimethylimidodicarbonimidic diamide hydrochloride
1,1-Dimethylbiguanide monohydrochloride
HSDB 7080
EINECS 214-230-6
NSC 91485
NSC-91485
CHEBI:6802
D.B.I.
D 15095
DTXSID9037246
AI3-51264
RIOMET ER
Biguanide, 1,1-dimethyl-, monohydrochloride
EX404
UNII-786Z46389E
EX-404
786Z46389E
DTXCID7017246
EC 214-230-6
BIGUANIDE, 1,1-DIMETHYL-, HYDROCHLORIDE
NSC91485
Glifage
Siofor
Metformin hydrochloride [USAN:USP:JAN]
KAZANO COMPONENT METFORMIN HYDROCHLORIDE
XIGDUO COMPONENT METFORMIN HYDROCHLORIDE
JANUMET COMPONENT METFORMIN HYDROCHLORIDE
METAGLIP COMPONENT METFORMIN HYDROCHLORIDE
QTERNMET COMPONENT METFORMIN HYDROCHLORIDE
INVOKAMET COMPONENT METFORMIN HYDROCHLORIDE
GLUCOVANCE COMPONENT METFORMIN HYDROCHLORIDE
SEGLUROMET COMPONENT METFORMIN HYDROCHLORIDE
ACTOPLUS MET COMPONENT METFORMIN HYDROCHLORIDE
QTERNMET XR COMPONENT METFORMIN HYDROCHLORIDE
TRIJARDY XR COMPONENT METFORMIN HYDROCHLORIDE
KOMBIGLYZE XR COMPONENT METFORMIN HYDROCHLORIDE
HCl, Metformin
METFORMIN HYDROCHLORIDE (MART.)
METFORMIN HYDROCHLORIDE [MART.]
METFORMIN HYDROCHLORIDE (USP-RS)
METFORMIN HYDROCHLORIDE [USP-RS]
Metformin hydrochloride (USAN:USP:JAN)
METFORMIN HYDROCHLORIDE (EP MONOGRAPH)
METFORMIN HYDROCHLORIDE [EP MONOGRAPH]
METFORMIN HYDROCHLORIDE (USP MONOGRAPH)
METFORMIN HYDROCHLORIDE [USP MONOGRAPH]
Hydrochloride, Metformin
Glucoformin
Dimefor
metformin-hcl
Glucophage ER
Compresso MF 95P
Metformin Hydrochoride
Metformin ER 500 mg
Metformin ER 750 mg
Metformin hydrochlorideER
Metformin Hydrochloride ER
Metformin Hydrochloride Tablet
METFORMIN HYDROCHLORIDEE/R
Metformin Hydrochloride Oral Solution
Metformin Hydrochloride Extended-Release
Metformin Hydrochloride Extended-Release 500mg
Metformin Hydrochloride Extended-Release Tablets
METFORMIN HYDROCHLORIDE COMPONENT OF JANUMET
METFORMIN HYDROCHLORIDE COMPONENT OF KAZANO
METFORMIN HYDROCHLORIDE COMPONENT OF XIGDUO
METFORMIN HYDROCHLORIDE COMPONENT OF METAGLIP
METFORMIN HYDROCHLORIDE COMPONENT OF QTERNMET
METFORMIN HYDROCHLORIDE COMPONENT OF SYNJARDY
JENTADUETO COMPONENT OF METFORMIN HYDROCHLORIDE
METFORMIN HYDROCHLORIDE COMPONENT OF GLUCOVANCE
METFORMIN HYDROCHLORIDE COMPONENT OF INVOKAMET
METFORMIN HYDROCHLORIDE COMPONENT OF JENTADUETO
METFORMIN HYDROCHLORIDE COMPONENT OF SEGLUROMET
METFORMIN HYDROCHLORIDE COMPONENT OF ACTOPLUS MET
METFORMIN HYDROCHLORIDE COMPONENT OF KOMBIGLYZE XR
METFORMIN HYDROCHLORIDE COMPONENT OF QTERNMET XR
METFORMIN HYDROCHLORIDE COMPONENT OF TRIJARDY XR
N,N-Dimethylimidodicarbonimidic Diamide Monohydrochloride
214-230-6
Glucophage
Glumetza
Diabex
Glucophage XR
Metformin (hydrochloride)
15537-72-1
1 1-DIMETHYLBIGUANIDE HYDROCHLORIDE
MFCD00012582
LA 6023
3-(diaminomethylidene)-1,1-dimethylguanidine;hydrochloride
1-carbamimidamido-N,N-dimethylmethanimidamide hydrochloride
N-[amino(dimethylamino)methylidene]guanidine hydrochloride
MLS000028493
C4H12ClN5
Metformin hydrochloride [USAN]
NCGC00016564-01
SMR000058277
1,1-Dimethylbiguanide, Hydrochloride
CAS-1115-70-4
Glucophage (TN)
DMBG hydrochloride
N,N-Dimethylimidodicarbonimidic diamide hydrochloride;Diabetosan;Diabex;1,1-Dimethylbiguanide hydrochloride
Prestwick_519
Metforminhydrochloride
Imidodicarbonimidic diamide, N,N-dimethyl-, hydrochloride (1:1)
Metformin HCl(Glucophage)
CHEMBL1703
SCHEMBL22977
MLS002222221
SPECTRUM1505814
N,N-dimethyl-imidodicarbonimidic diamide hydrochloride
1-dimethylbiguanide hydrochloride
Metformin hydrochloride (mM/ml)
SCHEMBL10325580
SCHEMBL20140191
CFQMNUQANAMQBI-UHFFFAOYSA-N
HMS1568A09
HMS1922H14
HY-17471AR
Pharmakon1600-01505814
Metformin HCl - Bio-X trade mark
BCP03594
Metformin hydrochloride (Glucophage)
METFORMIN HYDROCHLORIDE [MI]
Tox21_110498
HB2153
HY-17471A
Metformin (hydrochloride) (Standard)
Metformin hydrochloride (JP18/USP)
METFORMIN HYDROCHLORIDE [JAN]
NSC759262
s1950
METFORMIN HYDROCHLORIDE [HSDB]
N',N'-dimethylbiguanide hydrochloride
AKOS015894259
AKOS037515743
Tox21_110498_1
AC-2075
CCG-208004
CS-1851
FM25131
KS-1272
LA 6063
METFORMIN HYDROCHLORIDE [VANDF]
NSC-759262
SB19704
METFORMIN HYDROCHLORIDE [WHO-DD]
Biguanide,1-dimethyl-, monohydrochloride
NCGC00016564-06
NCGC00095185-01
NCGC00095185-02
BM164663
BP-12830
METFORMIN HYDROCHLORIDE [EMA EPAR]
SY001217
1,1-Dimethylbiguanide hydrochloride, 97%
DB-018697
M2009
METFORMIN HYDROCHLORIDE [ORANGE BOOK]
NS00076456
EN300-30323
D00944
EN300-26258648
ZITUVIMET COMPONENT METFORMIN HYDROCHLORIDE
SR-05000001764-2
Q27089363
F2173-0894
Z2244578658
Imidodicarbonimidic diamide,N-dimethyl-, monohydrochloride
(E)-N-[amino(dimethylamino)methylidene]guanidine hydrochloride
Metformin Hydrochloride 1.0 mg/ml in Methanol (as free base)
[(E)-[amino(dimethylamino)methylidene]amino]methanimidamide hydrochloride
1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide hydrochloride
Metformin hydrochloride, British Pharmacopoeia (BP) Reference Standard
Metformin hydrochloride, European Pharmacopoeia (EP) Reference Standard
Metformin hydrochloride, United States Pharmacopeia (USP) Reference Standard
Metformin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material
Metformin hydrochloride, pharmaceutical secondary standard; traceable to USP and PhEur