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Ninhydrin

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Identification
Molecular formula
C9H6O4
CAS number
485-47-2
IUPAC name
3-[(dibutylamino)methyl]-4,5,6-trihydroxy-3H-isobenzofuran-1-one
State
State

At room temperature, ninhydrin is typically in a solid state.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.00
Boiling point (Celsius)
260.00
Boiling point (Kelvin)
533.00
General information
Molecular weight
200.15g/mol
Molar mass
200.1490g/mol
Density
1.4990g/cm3
Appearence

Ninhydrin appears as a white or pale yellow crystalline powder. It can also exist in the form of small crystalline needles.

Comment on solubility

Solubility of 3-[(Dibutylamino)methyl]-4,5,6-trihydroxy-3H-isobenzofuran-1-one

The solubility of 3-[(dibutylamino)methyl]-4,5,6-trihydroxy-3H-isobenzofuran-1-one can be influenced by several factors, including its chemical structure and functional groups. Understanding its solubility profile is crucial for applications in various scientific fields. Here are some key points to consider:

  • Polarity: The presence of hydroxyl groups in this compound generally enhances its polarity, making it more soluble in polar solvents such as water.
  • Hydrophobic Interactions: The dibutylamino group increases the molecule's hydrophobic character, which may reduce its solubility in aqueous environments.
  • Solvent Compatibility: It is likely to be more soluble in organic solvents like ethanol or acetone compared to non-polar solvents due to its structural features.
  • Temperature Effects: Solubility may also vary significantly with changes in temperature; higher temperatures often increase the solubility of many organic compounds.

In summary, while 3-[(dibutylamino)methyl]-4,5,6-trihydroxy-3H-isobenzofuran-1-one exhibits a blend of hydrophilic and hydrophobic characteristics, its solubility largely depends on the solvent used, the temperature, and the specific interactions that take place between the compound and the solvent molecules.

Interesting facts

Interesting Facts about 3-[(Dibutylamino)methyl]-4,5,6-trihydroxy-3H-isobenzofuran-1-one

This unique compound is a fascinating example of organic chemistry, representing a blend of functional groups that provide a variety of interesting properties and potential applications. Here are some intriguing facts about this compound:

  • Structural Diversity: The structure of this compound features a trihydroxy isobenzofuran core, which is unusual and contributes to its distinct chemical behavior.
  • Biological Significance: Compounds like this one, with amino substitutions, may exhibit significant activity in biochemical pathways. This positions them as potential candidates for drug development or agricultural chemicals.
  • Solvent Properties: The dibutylamino group not only affects its solubility but could also play a role in enhancing the compound's affinity for biological membranes, which is critical for pharmacokinetics.
  • Applications in Research: Studies have shown that similar compounds can act as useful reagents in organic synthesis, where they can serve as intermediates or catalysts in various reactions.

Furthermore, the exploration of such compounds often raises questions about their environmental impact and sustainability. As “chemistry is the art of transformation”, understanding the implications of compounds like this one is essential in guiding future research and development efforts.

In conclusion, 3-[(dibutylamino)methyl]-4,5,6-trihydroxy-3H-isobenzofuran-1-one exemplifies the complexity and richness of organic compounds and their potential roles in science and technology.

Synonyms
Anthallan
520-47-8
Anthallan free base
3-[(dibutylamino)methyl]-4,5,6-trihydroxy-3H-2-benzofuran-1-one
70K7ST68DA
Phthalide, 3-((dibutylamino)methyl)-4,5,6-trihydroxy-
1(3H)-Isobenzofuranone, 3-((dibutylamino)methyl)-4,5,6-trihydroxy-
BRN 0298959
UNII-70K7ST68DA
3-((Dibutylamino)methyl)-4,5,6-trihydroxyphthalide
4-18-00-08146 (Beilstein Handbook Reference)
SCHEMBL9770590
DTXSID00966334
Q27265871
3-[(dibutylamino)methyl]-4,5,6-trihydroxy-2-benzofuran-1(3H)-one
3-DIBUTYLAMINOMETHYL-4,5,6-TRIHYDROXY-1-ISOBENZOFURANONE