3-(Dibutylamino)propyl 4-ethoxy-3-fluorobenzoate

Identification

Molecular formula

C₂₀H₃₂FNO₃

CAS number

220991-20-8

IUPAC name

3-(dibutylamino)propyl 4-ethoxy-3-fluoro-benzoate

State

It is typically a liquid at room temperature, owing to its relatively low melting point and its molecular structure that favors a liquid state.

Melting point (Celsius)

-5.40

Melting point (Kelvin)

267.75

Boiling point (Celsius)

353.20

Boiling point (Kelvin)

626.35

General information

Molecular weight

381.51g/mol

Molar mass

381.5140g/mol

Density

1.0623g/cm³

Appearence

3-(Dibutylamino)propyl 4-ethoxy-3-fluorobenzoate is generally observed as a pale yellow to colorless liquid. It has a slightly oily consistency.

Comment on solubility

Solubility of 3-(dibutylamino)propyl 4-ethoxy-3-fluoro-benzoate

3-(dibutylamino)propyl 4-ethoxy-3-fluoro-benzoate is a complex organic compound whose solubility can be influenced by various factors. Here are some critical aspects to consider:

Polarity: This compound contains both polar and non-polar functional groups. The dibutylamino group is non-polar, while the ethoxy group has polar characteristics, suggesting the compound has mixed polarity.
Solvent Interaction: In general, compounds with similar polarity will dissolve in each other. Therefore, 3-(dibutylamino)propyl 4-ethoxy-3-fluoro-benzoate is likely to be soluble in polar organic solvents such as:

Ethyl acetate
Acetone
Dichloromethane

Water Solubility: Due to the large non-polar dibutylamino group, this compound is expected to have limited solubility in water, making it less suitable for aqueous environments.
Temperature Effects: Like many organic compounds, solubility may increase with temperature. Higher temperatures can disrupt intermolecular forces, aiding dissolution.

In summary, while 3-(dibutylamino)propyl 4-ethoxy-3-fluoro-benzoate is expected to show good solubility in less polar organic solvents, its solubility in water is considered minimal due to its structural characteristics. Understanding these solubility parameters is essential for practical applications in various chemical processes.

Interesting facts

Interesting Facts about 3-(Dibutylamino)propyl 4-ethoxy-3-fluoro-benzoate

3-(Dibutylamino)propyl 4-ethoxy-3-fluoro-benzoate is a fascinating chemical compound that showcases the intricate interplay between organic chemistry and medicinal applications. Here are some intriguing aspects of this compound:

Biological Applications: Compounds like this one often serve as intermediates in the synthesis of pharmaceuticals. The presence of the dibutylamino group makes it potentially useful in drug design.
Fluorinated Compounds: The incorporation of fluorine in chemical structures can greatly influence their biological behavior. In this compound, the ³-fluoro substitution can enhance metabolic stability and lipophilicity, making it an interesting candidate for study.
Versatile Functional Groups: This compound contains a variety of functional groups, including esters and amines. Such diversity enables it to engage in numerous chemical reactions, facilitating its use in subsequent synthetic pathways.
Potential Research Focus: As researchers explore the properties and effects of compounds like this one, they may uncover novel applications in areas such as medicinal chemistry and material science.
Synthetic Challenges: The synthesis of this compound can present challenges due to the need for precise control over reaction conditions, which is a common theme in the creation of complex organic molecules.

This compound is a testament to the creativity and precision involved in organic synthesis, illustrating how small modifications can lead to significant changes in function and behavior. As research continues, who knows what exciting discoveries await in the realm of chemical compounds like 3-(dibutylamino)propyl 4-ethoxy-3-fluoro-benzoate?