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3-(dibutylamino)propyl 4-fluoro-3-iodo-benzoate hydrochloride

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Identification
Molecular formula
C17H24ClFINO2
CAS number
1443436-91-8
IUPAC name
3-(dibutylamino)propyl 4-fluoro-3-iodo-benzoate;hydrochloride
State
State

Under standard conditions, 3-(dibutylamino)propyl 4-fluoro-3-iodo-benzoate hydrochloride is typically found in a crystalline solid form.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
500.00
Boiling point (Kelvin)
773.15
General information
Molecular weight
446.87g/mol
Molar mass
446.8700g/mol
Density
1.2000g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder. Its color and texture may vary slightly depending on its purity and form (for example, hydrate vs. anhydrous).

Comment on solubility

Solubility of 3-(dibutylamino)propyl 4-fluoro-3-iodo-benzoate; hydrochloride

This compound, 3-(dibutylamino)propyl 4-fluoro-3-iodo-benzoate; hydrochloride, demonstrates notable solubility characteristics that are significant for its application in various fields.

  • Solubility in Water: Being a salt form (hydrochloride), it is generally anticipated to have good solubility in polar solvents such as water. The presence of the ionic hydrochloride group enhances its ability to dissociate and interact favorably with water molecules.
  • Solubility in Organic Solvents: The compound may exhibit variable solubility in organic solvents due to its hydrophobic dibutylamino groups. While it may dissolve in:
    • Alcohols (e.g., ethanol, methanol)
    • Aromatic hydrocarbons (e.g., toluene)
    the degree of solubility is heavily dependent on temperature and the particular solvent polarity.

It is essential to conduct solubility tests in various solvents to establish the compound’s behavior thoroughly. As a general rule, the more polar the solvent, the better the solubility for this compound, which includes compounds with quaternary ammonium structures.

In summary, the unique structural components of 3-(dibutylamino)propyl 4-fluoro-3-iodo-benzoate; hydrochloride suggest it will be soluble in both polar and non-polar solvents, making it versatile in its applications.

Interesting facts

Discovering 3-(Dibutylamino)propyl 4-fluoro-3-iodo-benzoate Hydrochloride

3-(Dibutylamino)propyl 4-fluoro-3-iodo-benzoate hydrochloride is a fascinating compound that bridges the realms of pharmaceutical chemistry and organic synthesis. Here are some intriguing aspects of this compound:

  • Pharmacological Potential: This compound shows promise in medicinal chemistry, where modifications to the benzoate moiety can create molecules with enhanced therapeutic effects.
  • Unique Substituents: The presence of a fluoro and an iodo group on the benzene ring introduces interesting electronic properties, influencing reactivity and biological activity.
  • Role of Dibutylamino Group: The dibutylamino group allows improved solubility in organic compounds, highlighting how functional groups can dramatically alter a compound's behavior.
  • Hydrochloride Salt Formation: The formation of hydrochloride salt is crucial in enhancing the stability and solubility of the compound, often leading to better bioavailability in pharmaceutical applications.

In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This compound serves as a reminder of the creativity involved in designing molecules with specific properties and functions.

Overall, 3-(dibutylamino)propyl 4-fluoro-3-iodo-benzoate hydrochloride exemplifies the rich interplay between structure and function in organic chemistry, making it an intriguing subject of study for chemists and pharmacologists alike.

Synonyms
455-80-1
4-Fluoro-3-iodobenzoic acid, 3-(dibutylamino)propyl ester, hydrochloride
Hydrochloride of the di-n-butylaminopropyl 3-iodo-4-fluorobenzoate
Dibutylaminopropyl 3-iodo-4-fluorobenzoate Hydrochloride
Dibutylaminopropyl 3-iodo-4-fluorobenzoate HCl
DTXSID00196538
BENZOIC ACID, 4-FLUORO-3-IODO-, 3-(DIBUTYLAMINO)PROPYL ESTER, HYDROCHLORIDE
DTXCID40119029