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DBF

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Identification
Molecular formula
C17H27ClFNO2
CAS number
55219-65-3
IUPAC name
3-(dibutylamino)propyl 4-fluorobenzoate;hydrochloride
State
State

At room temperature, DBF hydrochloride is generally found in a solid state.

Melting point (Celsius)
178.50
Melting point (Kelvin)
451.65
Boiling point (Celsius)
390.70
Boiling point (Kelvin)
663.85
General information
Molecular weight
327.86g/mol
Molar mass
327.8500g/mol
Density
1.0580g/cm3
Appearence

DBF hydrochloride typically appears as a white to off-white crystalline powder. It is hygroscopic, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of 3-(dibutylamino)propyl 4-fluorobenzoate hydrochloride

The solubility of 3-(dibutylamino)propyl 4-fluorobenzoate hydrochloride can be characterized by several key factors:

  • Solvent Polarity: This compound is likely to be soluble in polar solvents such as water and alcohols due to the presence of the hydrochloride functional group, which enhances its ionic character.
  • Hydrogen Bonding: The presence of the ammonium group from the dibutylamino moiety suggests potential hydrogen bond interactions with water, contributing to increased solubility.
  • Long-Chain Aliphatic Groups: The dibutyl groups may introduce lipophilic character, which could limit solubility in highly polar solvents but may improve solubility in organic solvents.
  • Temperature Dependence: As with many compounds, solubility may increase with temperature, making it necessary to consider this when preparing solutions.

In summary, the solubility of 3-(dibutylamino)propyl 4-fluorobenzoate hydrochloride is influenced by its unique structure, solvent environment, and temperature, making it important to experimentally determine the exact solubility in specific conditions for practical applications.

Interesting facts

Interesting Facts about 3-(Dibutylamino)propyl 4-fluorobenzoate Hydrochloride

3-(Dibutylamino)propyl 4-fluorobenzoate hydrochloride is a fascinating compound that plays a significant role in various chemical applications. Here are some captivating aspects of this compound:

  • Pharmaceutical Relevance: This compound is often examined in the context of pharmaceutical research due to its potential as a drug carrier or a precursor in drug synthesis. Its structure suggests probable interactions with biological systems, making it an interesting subject for medicinal chemistry.
  • Fluorine’s Impact: The presence of fluorine in the 4-position of the benzoate moiety enhances the compound's lipophilicity and metabolic stability, which are critical attributes in drug design. Fluorinated compounds are known for their unique properties, allowing them to perform well in various biological interactions.
  • Amine Functionality: The dibutylamino group provides a basic functionality to the compound, which can be pivotal in its interaction with different targets. Amines are known for their role in influencing pharmacokinetics, thereby affecting the efficacy of drugs.
  • Role in Synthesis: As a synthetic intermediate, this compound can be utilized to create a variety of other chemical entities by participating in substitution reactions or coupling reactions, demonstrating the versatility of this kind of chemical structure.
  • Research Implications: Studies involving derivatives of this compound can enhance our understanding of how chemical modifications impact biological activity. Researchers may explore its behavior in biological assays to uncover its potential therapeutic applications.

Overall, the multifunctional characteristics of 3-(dibutylamino)propyl 4-fluorobenzoate hydrochloride not only make it a compound of interest in the laboratory but also highlight its significance in advancing medicinal chemistry.

Synonyms
Dibutylaminopropyl p-fluorobenzoate hydrochloride
451-64-9
BENZOIC ACID, p-FLUORO, DIBUTYLAMINOPROPYL ESTER, HYDROCHLORIDE
DTXSID10196382
DTXCID20118873