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Etofedrine

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Identification
Molecular formula
C18H27NO3
CAS number
77-66-7
IUPAC name
[3-(diethylamino)-2,2-dimethyl-propyl] 3-hydroxy-2-phenyl-propanoate
State
State

At room temperature, etofedrine is in the form of a solid, specifically a crystalline powder.

Melting point (Celsius)
65.00
Melting point (Kelvin)
338.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
297.41g/mol
Molar mass
297.4100g/mol
Density
1.0686g/cm3
Appearence

Etofedrine typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of [3-(diethylamino)-2,2-dimethyl-propyl] 3-hydroxy-2-phenyl-propanoate

The solubility of the compound [3-(diethylamino)-2,2-dimethyl-propyl] 3-hydroxy-2-phenyl-propanoate is influenced by a variety of factors due to its complex structure. Understanding these factors is crucial for applications in pharmaceuticals and other chemical industries. Here are some key points to consider:

  • Polarity: The presence of both hydrophobic (the phenyl and diethylamino groups) and hydrophilic (the hydroxyl group) regions in the molecule can lead to variable solubility in different solvents.
  • Solvent Interaction: This compound may demonstrate significant solubility in polar organic solvents such as ethanol or acetone, while showing limited solubility in non-polar solvents like hexane.
  • pH Sensitivity: The solubility can be affected by the pH of the solution, especially due to the presence of the hydroxyl group, which can ionize and enhance solubility in acidic or basic conditions.
  • Temperature Effects: Increased temperature generally increases solubility for many organic compounds, and this compound may follow that trend.

As a result, the solubility of [3-(diethylamino)-2,2-dimethyl-propyl] 3-hydroxy-2-phenyl-propanoate is not only dependent on its intrinsic properties but also critically linked to the surrounding environment. Understanding these solubility characteristics can facilitate more effective usage and application in various scientific fields.

Interesting facts

Interesting Facts about [3-(diethylamino)-2,2-dimethyl-propyl] 3-hydroxy-2-phenyl-propanoate

This fascinating compound belongs to a class of organic compounds known as esters, which play a crucial role in various biological and industrial processes. Here are some notable aspects of this compound:

  • Biological Activity: Compounds similar to [3-(diethylamino)-2,2-dimethyl-propyl] 3-hydroxy-2-phenyl-propanoate are often studied for their pharmacological properties, making them potential candidates for drug development.
  • Synthetic Versatility: The diethylamino group in this compound suggests that it could be synthesized through a variety of methods, allowing flexibility in organic synthesis, particularly in medicinal chemistry.
  • Functional Groups: The presence of both the diethylamino and hydroxy groups highlights its potential for hydrogen bonding, which can affect its solubility and reactivity.
  • Reactivity: This compound may engage in different chemical reactions, such as esterification or nucleophilic substitution, which are vital in crafting complex organic molecules.
  • Potential Applications: Esters like this one are often used in flavors, fragrances, and as solvents, showcasing the compound’s relevance in various industries.

As a chemistry student or professional, understanding such compounds is essential because they reveal much about how molecular structure influences function. As one prominent chemist once said, "The beauty of chemistry lies in its ability to connect the molecular structure to the macroscopic properties of materials." Exploring [3-(diethylamino)-2,2-dimethyl-propyl] 3-hydroxy-2-phenyl-propanoate offers a glimpse into the interplay between chemical design and functional applications.

Synonyms
Amprotropine
148-32-3
UNII-Q1S268DPRS
Q1S268DPRS
[3-(diethylamino)-2,2-dimethylpropyl] 3-hydroxy-2-phenylpropanoate
Syntropan
Benzeneacetic acid, alpha-(hydroxymethyl)-, 3-(diethylamino)-2,2-dimethylpropyl ester
3-DIETHYLAMINO-2,2-DIMETHYLPROPYL TROPATE
(+/-)-3-DIETHYLAMINO-2,2-DIMETHYLPROPYL TROPATE
TROPIC ACID, 3-(DIETHYLAMINO)-2,2-DIMETHYLPROPYL ESTER
[3-(diethylamino)-2,2-dimethyl-propyl] 3-hydroxy-2-phenyl-propanoate
1-PROPANOL, 3-(DIETHYLAMINO)-2,2-DIMETHYL-, TROPATE (ESTER)
BENZENEACETIC ACID, .ALPHA.-(HYDROXYMETHYL)-, 3-(DIETHYLAMINO)-2,2-DIMETHYLPROPYL ESTER
AC1L1RF1
AC1Q62RN
(3-(diethylamino)-2,2-dimethyl-propyl) 3-hydroxy-2-phenyl-propanoate
(S)-amprotropine
CHEBI:2685
CHEMBL4302313
DTXSID90933277
Q5673348
Q27105766
3-(diethylamino)-2,2-dimethylpropyl 3-hydroxy-2-phenylpropanoate