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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
3-(diethylamino)-N-phenyl-butanamide
State
State

At room temperature, Lidocaine is in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.80
Boiling point (Kelvin)
623.95
General information
Molecular weight
234.34g/mol
Molar mass
234.3420g/mol
Density
0.9940g/cm3
Appearence

Lidocaine is typically encountered as a white crystalline powder. It is odorless and has a slightly bitter taste. In its pure form, it may appear in fine crystals or as a powder.

Comment on solubility

Solubility of 3-(diethylamino)-N-phenyl-butanamide

The solubility of 3-(diethylamino)-N-phenyl-butanamide in various solvents can be quite intriguing. This compound, with its relatively complex structure, exhibits specific solubility characteristics. Here are some key points to consider:

  • Amphipathic Nature: The presence of both hydrophobic and hydrophilic regions in the molecule suggests varied solubility behaviors.
  • Solvent Interaction: Typically, similar polarities enhance solubility; therefore, polar solvents such as methanol or ethanol might facilitate better dissolution.
  • Hydrophobic Effects: The diethylamino and phenyl groups contribute to the compound's overall hydrophobicity, potentially reducing solubility in water.

In summary: 3-(diethylamino)-N-phenyl-butanamide is likely more soluble in organic solvents than in aqueous solutions. As always, actual solubility can vary based on specific conditions such as temperature and pH.

Interesting facts

Interesting Facts about 3-(Diethylamino)-N-phenyl-butanamide

3-(Diethylamino)-N-phenyl-butanamide is a fascinating compound that falls within the category of amides, which are known for their roles in various biological processes and industrial applications. Here are some notable points that reflect its significance:

  • Pharmaceutical Relevance: This compound is often studied for its potential applications in pharmacology. The diethylamino group can enhance the compound's ability to interact with biological receptors, possibly leading to new therapeutic agents.
  • Structure-Activity Relationship: The unique structural arrangement of 3-(diethylamino)-N-phenyl-butanamide allows chemists to explore its activity by modifying different functional groups. This can lead to the development of more effective compounds in medicinal chemistry.
  • Synthetic Versatility: The synthesis of this compound often employs methods utilizing amine alkylation and amide coupling. This versatility makes it an interesting subject for synthetic chemists looking to understand complex organic reactions.
  • Toxicological Studies: Compounds such as this are crucial in toxicological assessments. Understanding their mechanisms can help in evaluating their safety profiles for potential use in the pharmacological field.

In a broader context, the study of 3-(diethylamino)-N-phenyl-butanamide highlights the importance of molecular design in creating compounds with specific, desired properties. As one researcher aptly put it: "The magic of chemistry lies in the ability to shape molecules and thereby shape our understanding of the nature around us."

With a wealth of potential uses and a structural complexity that invites exploration, 3-(diethylamino)-N-phenyl-butanamide exemplifies the dynamic and engaging nature of modern chemistry.

Synonyms
Octacaine
Amplicaine
13912-77-1
3-(Diethylamino)-N-phenylbutanamide
Octacaine [INN]
3-Diethylaminobutyranilide
Octacaina
Butanamide, 3-(diethylamino)-N-phenyl-
3-(Diethylamino)butyranilide
5BZF8S8IL5
Octacainum
3-Diethylaminobutyranilid
UNII-5BZF8S8IL5
Octacain
Butyranilide, 3-(diethylamino)-
beta-Diethylaminobuttersaeureanilid
OCTACAINE [MI]
OCTACAINE [WHO-DD]
SCHEMBL24818
orb1695826
CHEMBL2104563
NIOSH/ES5238400
DTXSID70864454
CHEBI:134953
HKOURKRGAFKVFP-UHFFFAOYSA-N
NAA91277
AKOS040753351
3-(Diethylamino)-N-phenylbutanamide #
ES52384000
NS00006958
Q27888312
Octacaine; 3-(Diethylamino)butyranilide; 3-(Diethylamino)-N-phenyl-butanamide