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Nefopam

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Identification
Molecular formula
C20H23NO3
CAS number
13669-70-0
IUPAC name
3-(diethylamino)propyl 2-(2-furylmethyl)-3-(1-naphthyl)propanoate
State
State

At room temperature, Nefopam exists as a solid, which is typical for many organic medicinal compounds.

Melting point (Celsius)
212.00
Melting point (Kelvin)
485.15
Boiling point (Celsius)
307.00
Boiling point (Kelvin)
580.15
General information
Molecular weight
309.41g/mol
Molar mass
309.4130g/mol
Density
1.1360g/cm3
Appearence

Nefopam is typically seen as a white to off-white crystalline powder. Its appearance is consistent with many other similar organic compounds and can exhibit slight polymorphic variations.

Comment on solubility

Solubility of 3-(diethylamino)propyl 2-(2-furylmethyl)-3-(1-naphthyl)propanoate

The solubility of 3-(diethylamino)propyl 2-(2-furylmethyl)-3-(1-naphthyl)propanoate is a fascinating topic, as it showcases the interplay of various functional groups in a complex organic structure. This compound, characterized by its distinctive substituents, tends to exhibit moderate solubility in several organic solvents, primarily due to its hydrophobic naphthalene and furan rings that influence its interactions with solvents.

Key solubility characteristics include:

  • Polar Solvents: It may show limited solubility in polar solvents such as water, primarily due to its non-polar aromatic groups.
  • Non-Polar Solvents: Strong solubility is expected in non-polar solvents like toluene and hexane, favoring environments that can accommodate its hydrophobic nature.
  • Amphiphilic Behavior: The presence of the diethylamino group can potentially enhance solubility in polar aprotic solvents, such as DMSO or DMF, wherein hydrogen bonding can occur.

In summary, while 3-(diethylamino)propyl 2-(2-furylmethyl)-3-(1-naphthyl)propanoate demonstrates varying degrees of solubility depending on the solvent type, its practical solubility remains an intriguing aspect for further exploration in chemical applications. The multifaceted nature of solubility in such compounds reveals the importance of their molecular architecture.

Interesting facts

Interesting Facts about 3-(diethylamino)propyl 2-(2-furylmethyl)-3-(1-naphthyl)propanoate

3-(diethylamino)propyl 2-(2-furylmethyl)-3-(1-naphthyl)propanoate is an intriguing compound with various potential applications in the fields of pharmacology and organic chemistry. Here are some fascinating aspects to consider:

  • Pharmacological Potential: Due to its structural complexity, this compound could exhibit interesting biological activities. Its derivatives may show potential in drug development, especially in targeting specific receptors in the body.
  • Aromatic Influence: The presence of naphthalene and furan moieties contributes to the compound's unique properties. Naphthalene is known for its aromaticity and stability, while furan units often participate in electrochemical reactions, making this compound an interesting subject for study.
  • Diethylamino Group: The diethylamino functional group is well-known for its role in enhancing solubility and bioavailability of organic compounds. This could potentially make the compound more effective as a pharmaceutical agent.
  • Research Applications: Scientists are drawn to compounds like this for their diverse applications in research. Investigating their behavior in various solvents and under different conditions can lead to discoveries in material science and molecular electronics.
  • Structure-Activity Relationship: Understanding the interactions between this compound’s complex structure and its biological activities can pave the way for the development of novel therapeutic agents.

In summary, 3-(diethylamino)propyl 2-(2-furylmethyl)-3-(1-naphthyl)propanoate represents a fascinating intersection of organic chemistry and pharmacology, making it a compelling subject for both research and application.