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Ketoprofen

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Identification
Molecular formula
C16H14O3
CAS number
22071-15-4
IUPAC name
3-(diethylamino)propyl 2-hydroxy-3-methyl-2-phenyl-butanoate
State
State

Ketoprofen is typically a solid at room temperature and can exist in crystalline form.

Melting point (Celsius)
94.50
Melting point (Kelvin)
367.70
Boiling point (Celsius)
426.60
Boiling point (Kelvin)
699.80
General information
Molecular weight
254.29g/mol
Molar mass
254.2850g/mol
Density
1.1470g/cm3
Appearence

Ketoprofen is typically encountered as a white or off-white crystalline powder. It is known to be odorless.

Comment on solubility

Solubility of 3-(diethylamino)propyl 2-hydroxy-3-methyl-2-phenyl-butanoate

The solubility of 3-(diethylamino)propyl 2-hydroxy-3-methyl-2-phenyl-butanoate can be influenced by several factors, making it an interesting compound to study in this regard. Here are key considerations regarding its solubility:

  • Polar vs. Non-Polar Characteristics: Given the presence of hydrophilic (water-attracting) -OH (hydroxy) groups and the relatively bulky hydrophobic (water-repelling) aromatic phenyl group, solubility may be affected in aqueous solutions.
  • Solvent Dependence: This compound may exhibit different solubility behavior in various solvents, such as:
    • High solubility in polar solvents like water or ethanol due to its polar functional groups.
    • Lower solubility in non-polar solvents like hexane, which cannot effectively solvate the polar parts of the molecule.
  • pH Influence: The solubility could vary with changes in pH, as the charge state of the diethylamino group can significantly alter its interaction with solvents.

In conclusion, assessing the solubility of this compound requires careful consideration of its functional groups and the nature of the solvent used. As noted, “solubility is not an intrinsic property; it is determined in context.”

Interesting facts

Interesting Facts about 3-(Diethylamino)propyl 2-hydroxy-3-methyl-2-phenyl-butanoate

This compound, known to many as an intriguing member of the class of amides, showcases a unique structure that is of great interest in the field of medicinal chemistry. Here are some captivating insights about it:

  • Diverse Applications: This compound has been studied for its potential applications in pharmaceuticals. It plays a crucial role in drug formulations that target specific biological pathways.
  • Mechanism of Action: Research indicates that it may modulate neurotransmitter activity, which could make it valuable for understanding mental health disorders.
  • Structural Characteristics: The compound contains both an amine and an ester functional group, providing a balance of polar and nonpolar characteristics which can influence its reactivity.
  • Chirality: Its stereocenters mean that this compound can exist in different isomeric forms, which can have different biological activities. The study of these isomers can lead to more targeted therapies.
  • Historical Context: Compounds similar to this one have paved the way for developing various medicines, influencing research directions in synthetic chemistry and pharmacology.

As scientists delve deeper into the properties and applications of 3-(diethylamino)propyl 2-hydroxy-3-methyl-2-phenyl-butanoate, they open up new possibilities for creating innovative therapies that can significantly improve patient outcomes.

"The exploration of chemical compounds is not just about understanding their structures, but also about unlocking their potential to change lives."

Synonyms
BAY-1433 free base
090P31D8XK
UNII-090P31D8XK
15421-87-1
Mandelic acid, alpha-isopropyl-, 3-(diethylamino)propyl ester
Benzeneacetic acid, alpha-hydroxy-alpha-(1-methylethyl)-, 3-(diethylamino)propyl ester
Q27895858
MANDELIC ACID, .ALPHA.-ISOPROPYL-, 3-(DIETHYLAMINO)PROPYL ESTER
BENZENEACETIC ACID, .ALPHA.-HYDROXY-.ALPHA.-(1-METHYLETHYL)-, 3-(DIETHYLAMINO)PROPYL ESTER