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Cocaine

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Identification
Molecular formula
C17H21NO4
CAS number
50-36-2
IUPAC name
3-(diethylamino)propyl 2-phenylnorbornane-2-carboxylate
State
State
At room temperature, cocaine is typically in a solid state. It is usually encountered as a crystalline powder or in small rock form. Cocaine is commonly found as its hydrochloride salt, which is soluble in water.
Melting point (Celsius)
98.00
Melting point (Kelvin)
371.15
Boiling point (Celsius)
1 879.00
Boiling point (Kelvin)
2 152.00
General information
Molecular weight
303.35g/mol
Molar mass
303.3530g/mol
Density
1.3000g/cm3
Appearence
Cocaine typically appears as a crystalline powder that is white in color. It may sometimes appear as a fine, pearly substance or in small rock-like forms known as "rocks."
Comment on solubility

Solubility of 3-(diethylamino)propyl 2-phenylnorbornane-2-carboxylate

The solubility of 3-(diethylamino)propyl 2-phenylnorbornane-2-carboxylate can be influenced by various factors, particularly due to the complex structure of the compound. Understanding its solubility can be crucial for numerous applications in pharmaceuticals and organic chemistry.

Factors Affecting Solubility

  • Polarity: The presence of the diethylamino group hints at possible solubility in polar solvents due to its basic nature, while the phenyl and norbornane structures may contribute to hydrophobic characteristics.
  • Temperature: Increased temperature generally enhances solubility, especially for organic compounds; heating might increase the solubility of this compound in organic solvents.
  • pH Levels: Since this compound has an amine group, changes in pH could alter the ionization state, affecting its solubility in aqueous solutions.

In general, such compounds tend to exhibit limited solubility in water due to their organic character, but they may dissolve well in various organic solvents such as ethanol, dimethyl sulfoxide (DMSO), and chloroform. It is important to consider these traits when planning syntheses or applications.

Key Summary

To summarize:

  • Likely limited solubility in water
  • Better soluble in organic solvents
  • Solubility may vary with temperature and pH

Understanding these solubility aspects is critical for utilizing 3-(diethylamino)propyl 2-phenylnorbornane-2-carboxylate effectively in various chemical contexts.

Interesting facts

Interesting Facts about 3-(diethylamino)propyl 2-phenylnorbornane-2-carboxylate

3-(diethylamino)propyl 2-phenylnorbornane-2-carboxylate is a fascinating chemical compound that belongs to the class of carboxylates, exhibiting intriguing properties and potential applications.

Key Highlights:

  • Structure and Complexity: This compound features a unique bicyclic structure with a norbornane ring, which contributes to its stereochemical diversity and makes it an interesting subject of study in organic chemistry.
  • Pharmacological Potential: Compounds like this one are often explored for their pharmacological properties. The presence of the diethylamino group potentially enhances its bioactivity, making it relevant in medicinal chemistry.
  • Applications in Synthesis: The carboxylate functional group can serve as a versatile building block in organic synthesis, facilitating the formation of various derivatives used in drug development.
  • Research Relevance: Due to its structural characteristics, this compound may be used in research studies aimed at understanding receptor interactions, particularly in fields such as neuropharmacology.
  • Analytical Insight: The analytical study of such complex compounds often employs techniques like NMR spectroscopy and mass spectrometry, providing deeper insights into their molecular characteristics and behaviors.

As with many chemical compounds, the study of 3-(diethylamino)propyl 2-phenylnorbornane-2-carboxylate not only broadens our understanding of organic chemistry but also opens avenues for innovation in pharmaceuticals and materials science. It is a beautiful representation of how molecular architecture can influence function, presenting endless possibilities for exploration and discovery.

Synonyms
3-(diethylamino)propyl 2-phenylbicyclo[2.2.1]heptane-2-carboxylate
Bornaprine (INN)
3-(Diethylamino)propyl 2-phenyl-2-norbornanecarboxylate
Bornaprin
SCHEMBL924755
orb1739516
CHEMBL4297087
DTXSID20864944
BDNMABJZSXTKAQ-UHFFFAOYSA-N
CHEBI:135406
HY-121603
CS-0082830
NS00007463
D07302
Q4946040