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Procaine

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Identification
Molecular formula
C13H20N2O2
CAS number
59-46-1
IUPAC name
3-(diethylamino)propyl 2,2-diphenylacetate
State
State

At room temperature, procaine is in a solid state, typically handled as its hydrochloride salt form which is also solid. It is usually dissolved in water or other solvents for usage in medical applications as an anesthetic.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
396.80
Boiling point (Kelvin)
670.00
General information
Molecular weight
273.38g/mol
Molar mass
273.3760g/mol
Density
1.1000g/cm3
Appearence

Procaine is usually found as a white crystalline powder. It is odorless and has a slightly bitter taste. The compound is generally formulated as its hydrochloride to be used in medical applications, appearing as a white crystalline substance.

Comment on solubility

Solubility of 3-(diethylamino)propyl 2,2-diphenylacetate

The solubility of 3-(diethylamino)propyl 2,2-diphenylacetate can be quite interesting due to its unique structure. This compound possesses both polar and non-polar characteristics, which can significantly influence its solubility behavior in various solvents. Here are some key points to consider:

  • Polar Solvents: The diethylamino group contributes to the polar nature of the compound, enhancing its solubility in polar solvents such as water and ethanol.
  • Non-Polar Solvents: The presence of the diphenylacetate moiety, which is large and hydrophobic, may increase solubility in organic non-polar solvents such as chloroform and ethyl acetate.
  • Temperature Effects: The solubility can also be temperature-dependent, often increasing with a rise in temperature, thereby facilitating better interaction in the solvent.
  • Interactions: The formation of hydrogen bonds with polar solvents can enhance solubility, while van der Waals forces might play a role in non-polar solvent interactions.

In summary, understanding the solubility of 3-(diethylamino)propyl 2,2-diphenylacetate involves recognizing its dual nature, allowing it to dissolve in both types of solvents. This unique characteristic opens avenues for its application in diverse chemical environments. As a quote suggests, “The structure defines the solubility.”

Interesting facts

Interesting Facts about 3-(diethylamino)propyl 2,2-diphenylacetate

3-(diethylamino)propyl 2,2-diphenylacetate is a fascinating compound with several intriguing properties and uses. Here are some noteworthy aspects:

  • Pharmaceutical Importance: This compound has shown potential in pharmaceutical applications, particularly as a drug intermediate in the synthesis of various bioactive molecules.
  • Versatile Structure: The molecular architecture, featuring a diethylamino group, lends itself to diverse chemical reactions, enabling the development of numerous derivatives with varying biological activities.
  • Biological Activity: Some studies suggest that derivatives of this compound exhibit interesting pharmacological activities, including anticholinergic and antihistaminic effects, thus showcasing its relevance in medicinal chemistry.
  • Synthetic Pathways: Chemists appreciate the synthetic routes available for producing this compound, often involving straightforward modifications of existing compounds, which demonstrates its synthetic accessibility.
  • Research Potential: Ongoing research may uncover additional practical applications or novel derivatives, making it a compound worth exploring within the realms of organic and medicinal chemistry.

As one dives into the developmental aspects of 3-(diethylamino)propyl 2,2-diphenylacetate, the combination of its chemical structure and potential applications reflects the dynamic nature of chemical research and its importance in advancing healthcare.

Synonyms
ACETIC ACID, 2,2-DIPHENYL-, 3-(DIETHYLAMINO)PROPYL ESTER
BRN 2220614
3578-28-7
2,2-Diphenylacetic acid 3-(diethylamino)propyl ester
3-(Diethylamino)propyl 2,2-diphenyl acetate
DTXSID00189309
DTXCID80111800
3-(diethylamino)propyl 2,2-diphenylacetate
3-(diethylamino)propyl diphenylacetate
CHEMBL1619643
STK528119
AKOS005461020
NCGC00246246-01
NCGC00246246-02
NCGC00246246-04
AB00637873-08
AB00637873-11
AE-641/02528025