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Etoposide

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Identification
Molecular formula
C29H32O13
CAS number
33419-42-0
IUPAC name
3-(diethylamino)propyl 3-methyl-4-oxo-2-phenyl-chromene-8-carboxylate
State
State

At room temperature, Etoposide is in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
196.00
Melting point (Kelvin)
469.15
Boiling point (Celsius)
565.30
Boiling point (Kelvin)
838.45
General information
Molecular weight
588.57g/mol
Molar mass
588.5690g/mol
Density
1.1900g/cm3
Appearence

Etoposide appears as a white to slightly yellow crystalline powder.

Comment on solubility

Solubility of 3-(diethylamino)propyl 3-methyl-4-oxo-2-phenyl-chromene-8-carboxylate

The solubility of 3-(diethylamino)propyl 3-methyl-4-oxo-2-phenyl-chromene-8-carboxylate can be influenced by various physical and chemical factors. Key points to consider include:

  • Polarity: The presence of polar functional groups such as carboxylate can enhance solubility in polar solvents.
  • Solvent Choice: This compound is likely to be more soluble in organic solvents like ethanol, methanol, or acetone due to its organic structure.
  • Temperature Effects: Increasing temperature generally increases solubility for most organic compounds, which could apply here as well.
  • pH Influence: The carboxylate moiety may dissociate in more alkaline conditions, potentially increasing solubility in those environments.

As a general rule, compounds with large aromatic systems may exhibit lower water solubility due to hydrophobicity. Therefore, for 3-(diethylamino)propyl 3-methyl-4-oxo-2-phenyl-chromene-8-carboxylate, one might expect moderate solubility in organic solvents, but limited solubility in water.

In conclusion, understanding the solubility of such complex organic molecules involves considering multiple factors including functional groups, temperature, and solvent interactions. Each of these variables plays a crucial role in determining the overall solubility profile.

Interesting facts

Interesting Facts about 3-(Diethylamino)propyl 3-methyl-4-oxo-2-phenyl-chromene-8-carboxylate

This fascinating compound is part of a larger class of molecules known as chromenes, which are notable for their diverse biological activities. Here are some intriguing aspects:

  • Bioactivity: 3-(Diethylamino)propyl 3-methyl-4-oxo-2-phenyl-chromene-8-carboxylate has garnered attention in medicinal chemistry due to its potential anti-inflammatory and antioxidant properties. These activities could be useful in the development of new therapeutic agents.
  • Molecular Versatility: The presence of the diethylamino group enhances the compound’s ability to interact with biological targets, showcasing a remarkable example of how structural modifications can influence pharmacological profiles.
  • Synthetic Pathways: The synthesis of this compound can involve various reaction techniques, including condensation reactions and cyclization processes. Understanding these pathways is crucial for creating derivatives with improved efficacy or reduced side effects.
  • Applications in Research: Its unique structure makes it a compound of interest for studies focused on enzyme inhibition and receptor binding, making it a valuable tool in biochemical research.
  • Chromene Derivatives: Chromenes and their derivatives are recognized for their applications in dyes and pigments, showcasing the compound's potential versatility beyond medicinal applications.

This compound represents the intersection of organic chemistry and pharmacology, emphasizing the importance of structural intricacies in developing novel medicinal compounds. As research continues, it might reveal even more exciting applications and mechanisms of action.