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Benzocaine

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Identification
Molecular formula
C9H11NO2
CAS number
94-09-7
IUPAC name
3-(diethylamino)propyl 4-aminobenzoate
State
State

At room temperature, benzocaine is in a solid state. It is typically available as a crystalline powder that can be easily incorporated into pharmaceutical formulations.

Melting point (Celsius)
88.00
Melting point (Kelvin)
361.00
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.00
General information
Molecular weight
165.19g/mol
Molar mass
165.1890g/mol
Density
1.1710g/cm3
Appearence

Benzocaine appears as a white, odorless crystalline powder. It is commonly used in its pure form or as a component in topical pain relievers and anesthetic ointments. The compound has a slightly bitter taste and is insoluble in water, but soluble in organic solvents such as ethanol, chloroform, and ethyl ether.

Comment on solubility

Solubility of 3-(diethylamino)propyl 4-aminobenzoate

The solubility of 3-(diethylamino)propyl 4-aminobenzoate can be characterized by a few key factors. Understanding its behavior in various solvents is crucial for applications in chemical and pharmaceutical formulations.

Key aspects to consider about its solubility include:

  • Polarity: The presence of both amino and ether groups in the molecule suggests that this compound may exhibit a degree of polar character, potentially enhancing its solubility in polar solvents such as water.
  • Hydrogen Bonding: The amino groups can participate in hydrogen bonding, which may further facilitate its solubility in aqueous solutions.
  • Solvent Interaction: Compatibility with organic solvents like ethanol and acetone should also be observed, as the diethylamino group tends to make the compound more soluble in organic media.
  • pH Sensitivity: The solubility may vary significantly with pH, especially due to the ionization of the amino groups, which can affect its solubility profile.

In general, it can be said that 3-(diethylamino)propyl 4-aminobenzoate has a promising solubility profile in both polar and non-polar environments, making it a versatile component in various scientific applications. The combination of its structural features plays a significant role in determining how well it interacts with different solvents.

Interesting facts

Interesting Facts about 3-(diethylamino)propyl 4-aminobenzoate

3-(diethylamino)propyl 4-aminobenzoate is a fascinating compound that combines an amine functional group with a benzoate moiety, leading to interesting properties and applications. Here are some key insights into this compound:

  • Pharmacological Significance: This compound is often studied in the field of medicinal chemistry. Its structure suggests potential use as a drug or bioactive agent due to the presence of both an amine and a benzoate functional group.
  • Structure-Activity Relationship: The diethylamino group is known to influence the lipophilicity and overall biological activity of compounds, making it essential when designing new pharmaceuticals.
  • Potential Applications: Research into compounds like 3-(diethylamino)propyl 4-aminobenzoate has pointed toward applications in:
    • Antimicrobial agents
    • Anti-inflammatory drugs
    • Various receptor modulators
  • Synthesis Techniques: The synthesis of this compound can involve various organic chemistry techniques, including:
    • Alkylation reactions
    • Amination processes
    • Coupling reactions
  • Research Potential: The compound is a subject of ongoing research, particularly in fields targeting drug development and materials science, indicating versatility and adaptability for different applications.

Overall, 3-(diethylamino)propyl 4-aminobenzoate represents a significant link between organic chemistry and practical applications in various scientific fields. As researchers continue to delve into its properties, the potential benefits of this compound may unfold further, illustrating the beauty and complexity of chemical science.

Synonyms
SCHEMBL11640115