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Fluoxetine

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Identification
Molecular formula
C17H18FNO2
CAS number
56296-78-7
IUPAC name
3-(diethylamino)propyl 4-fluorobenzoate
State
State

Fluoxetine is typically found in a solid state at room temperature, commonly in the form of tablets or capsules for medicinal use.

Melting point (Celsius)
179.50
Melting point (Kelvin)
452.70
Boiling point (Celsius)
244.50
Boiling point (Kelvin)
517.70
General information
Molecular weight
309.34g/mol
Molar mass
309.3350g/mol
Density
1.0879g/cm3
Appearence

Fluoxetine appears as a white to off-white crystalline solid. It is usually odorless and tasteless. Its crystalline form can reflect light, making it somewhat shiny under certain angles and lighting.

Comment on solubility

Solubility of 3-(diethylamino)propyl 4-fluorobenzoate

3-(diethylamino)propyl 4-fluorobenzoate, a compound with both hydrophobic and hydrophilic characteristics, displays interesting solubility behavior that can vary widely depending on the solvent used. Here are some key points regarding its solubility:

  • Solvent Compatibility: This compound is likely to be soluble in organic solvents such as ethanol, acetone, and dichloromethane, which can effectively solvate its non-polar aromatic structure.
  • Water Solubility: Given the presence of the diethylamino group, which can engage in hydrogen bonding, partial solubility in water may be expected, although it is not highly soluble due to the large hydrophobic regions in the molecule.
  • Temperature Dependency: Like many organic compounds, the solubility may significantly increase with rising temperatures, allowing for greater dissolution in mixed solvents.
  • pH Sensitivity: The ionization of the amino group may alter solubility in acidic or basic conditions; in an acidic environment, it may become more soluble due to protonation leading to improved interactions with polar solvents.

Overall, while the solubility of 3-(diethylamino)propyl 4-fluorobenzoate in water might be limited, its behavior in various organic solvents makes it a versatile compound for synthesis and formulation applications.

Interesting facts

Interesting Facts about 3-(diethylamino)propyl 4-fluorobenzoate

3-(diethylamino)propyl 4-fluorobenzoate is a fascinating compound that holds significance in various fields, including pharmaceuticals and organic chemistry. Here are some intriguing insights:

  • Pharmaceutical Applications: This compound is often explored for its potential as an active pharmaceutical ingredient (API) due to its ability to interact with biological systems effectively. Its structural features allow it to modify biochemical pathways, which can lead to the development of new therapeutic agents.
  • Fluorine's Role: The presence of fluorine in the compound not only enhances its potency but also affects its biological activity and metabolic stability. Fluorinated compounds are known to exhibit unique properties, making them valuable in drug design.
  • Synthetic Relevance: The synthesis of 3-(diethylamino)propyl 4-fluorobenzoate can involve various modern organic synthesis techniques. This includes methods like nucleophilic substitution and esterification, which are fundamental in laboratory practices.
  • Chemical Behavior: As an ester, the compound may undergo hydrolysis under certain conditions, a reaction significant in both biological systems (like drug metabolism) and in synthetic applications where controlled degradation is desired.

In summary, 3-(diethylamino)propyl 4-fluorobenzoate is not merely a compound; it represents a intersection of chemistry, biology, and pharmacology. Its unique structure and properties offer a myriad of possibilities, igniting scientific curiosity and paving the way for innovative research.