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Lidocaine hydrochloride

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Identification
Molecular formula
C14H22N2O2HCl
CAS number
6108-05-0
IUPAC name
[3-(dimethylamino)-1,2-dimethyl-propyl] 4-aminobenzoate;hydrochloride
State
State

At room temperature, lidocaine hydrochloride is in a solid state, typically supplied as a powder for various applications.

Melting point (Celsius)
80.00
Melting point (Kelvin)
353.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
288.81g/mol
Molar mass
288.8140g/mol
Density
1.0025g/cm3
Appearence

Lidocaine hydrochloride appears as a white, crystalline powder. It is odorless and has a distinct taste.

Comment on solubility

Solubility of [3-(dimethylamino)-1,2-dimethyl-propyl] 4-aminobenzoate;hydrochloride

The solubility of [3-(dimethylamino)-1,2-dimethyl-propyl] 4-aminobenzoate;hydrochloride can be influenced by various factors due to its unique structure. This compound, being a hydrochloride salt, typically exhibits higher solubility in polar solvents compared to its free base form.

Key Points Regarding Its Solubility:

  • High Solubility in Water: As a hydrochloride salt, it is likely to be soluble in water, making it suitable for various aqueous applications.
  • Effect of Temperature: Increased temperature may enhance solubility further, promoting its dissolving capability.
  • Influence of pH: The solubility may vary with changes in pH, as the charge on the amine group can affect its behavior in solution.

In general, compounds of similar structure tend to exhibit high solubility due to their ionic nature in aqueous environments. As stated, they "dissociate into ions" which contributes to their increased solubility in water. Always consider these factors when assessing the solubility of chemical compounds, especially for pharmaceutical applications where solution behavior is crucial.

Interesting facts

Interesting Facts about [3-(dimethylamino)-1,2-dimethyl-propyl] 4-aminobenzoate; hydrochloride

This unique compound, often employed in pharmacological research, boasts an intriguing combination of properties that make it a subject of interest in the field of medicinal chemistry. Here are some noteworthy aspects:

  • Pharmacological Applications: The compound is frequently investigated for its potential as a pharmaceutical agent. Its structure suggests roles in drug formulations, particularly for conditions that require modulation of neurotransmitter activity.
  • Structure-Activity Relationship: The presence of both a dimethylamino group and a benzene derivative in its structure allows scientists to explore how variations affect its biological activity. This can lead to a better understanding of drug design and efficacy.
  • Solubility and Bioavailability: Being a hydrochloride salt, this compound typically exhibits enhanced solubility in biological systems compared to its base form. This characteristic can significantly influence the compound's bioavailability and absorption in vivo.
  • Synthetic Pathways: The synthesis of this compound often involves multi-step techniques, showcasing the complexity of organic synthesis in creating structurally diverse pharmaceuticals. Learning these pathways is critical for chemists aiming to create new compounds.
  • Research Opportunities: Due to its unique structural features, it presents opportunities for further research in areas such as receptor binding studies, pharmacodynamics, and toxicology.

Overall, the examination of [3-(dimethylamino)-1,2-dimethyl-propyl] 4-aminobenzoate; hydrochloride represents a captivating intersection of theoretical knowledge and practical application, embodying the essence of chemical study in the pharmaceutical realm. As one scientist noted, "Each compound tells a story; it's our job to uncover it."

Synonyms
Tutocaine hydrochloride
Butamin
532-62-7
3-(Dimethylamino)-1,2-dimethylpropyl p-aminobenzoate monohydrochloride
0CB4N35KTZ
3-Dimethylamino-1,2-dimethylpropyl p-aminobenzoate hydrochloride
Tutocaine HCl
EINECS 208-542-1
UNII-0CB4N35KTZ
3-Dimethyl-1,2-dimethylpropyl p-aminobenzoate hydrochloride
p-Aminobenzoyldimethylamino-1,2-dimethylpropanol hydrochloride
4-(Dimethylamino)-3-methyl-2-butanol 4-aminobenzoate (ester) hydrochloride
p-Aminobenzoic acid 3-(dimethylamino)-1,2-dimethylpropyl ester hydrochloride
TUTOCAIN HYDROCHLORIDE
TOTOCAINE HYDROCHLORIDE
DTXSID10967711
ZGKJESGFAPAQKB-UHFFFAOYSA-N
2-BUTANOL, 4-(DIMETHYLAMINO)-3-METHYL-, p-AMINOBENZOATE, MONOHYDROCHLORIDE
NS00080130
Q27236611
2-BUTANOL, 4-(DIMETHYLAMINO)-3-METHYL-, 4-AMINOBENZOATE (ESTER), MONOHYDROCHLORIDE
4-(Dimethylamino)-3-methylbutan-2-yl 4-aminobenzoate--hydrogen chloride (1/1)