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Procaine

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Identification
Molecular formula
C13H20N2O2
CAS number
59-46-1
IUPAC name
[3-(dimethylamino)-2-hydroxy-propyl] 4-(propylamino)benzoate
State
State

Procaine is solid at room temperature.

Melting point (Celsius)
61.20
Melting point (Kelvin)
334.35
Boiling point (Celsius)
400.00
Boiling point (Kelvin)
673.15
General information
Molecular weight
236.31g/mol
Molar mass
236.3060g/mol
Density
1.1234g/cm3
Appearence

Procaine typically appears as a white, crystalline solid. It is odorless and has a slightly bitter taste. The compound is often supplied in powdered form for use in various applications.

Comment on solubility

Solubility of [3-(dimethylamino)-2-hydroxy-propyl] 4-(propylamino)benzoate

The solubility of the compound [3-(dimethylamino)-2-hydroxy-propyl] 4-(propylamino)benzoate can be influenced by several factors, including its chemical structure, temperature, and the solvent used.

Key Factors Affecting Solubility:

  • Polarity: The presence of both amine and hydroxyl functional groups implies increased polarity, making the compound potentially more soluble in polar solvents such as water.
  • Hydrogen Bonding: The hydroxyl group may facilitate hydrogen bonding, enhancing solubility in water and alcohols.
  • Alkyl Chains: The propyl and dimethyl moieties can introduce hydrophobic characteristics, which may reduce solubility in highly polar solvents but enhance it in non-polar environments.

It’s essential to note that the solubility behavior may vary greatly depending on the specific conditions:

  • Temperature: Increased temperature can often enhance solubility.
  • pH Levels: Since the compound involves amine groups, pH can have a significant impact on its charge and, consequently, solubility.

In summary, while the solubility of [3-(dimethylamino)-2-hydroxy-propyl] 4-(propylamino)benzoate leans towards being soluble in polar solvents due to its functional groups, the overall solubility profile should be empirically determined under various conditions for optimal results.

Interesting facts

Interesting Facts about [3-(dimethylamino)-2-hydroxy-propyl] 4-(propylamino)benzoate

[3-(dimethylamino)-2-hydroxy-propyl] 4-(propylamino)benzoate is a compound whose structure suggests a fascinating interplay between several functional groups, potentially leading to various applications in the field of medicinal chemistry.

Unique Features

  • Dual Amino Groups: The presence of both dimethylamino and propylamino groups enhances the compound's pharmacological properties, possibly influencing its interaction with biological targets.
  • Hydroxyl Group: The hydroxy group contributes to the compound's ability to participate in hydrogen bonding, which can enhance solubility in biological systems and influence its efficacy as a drug.
  • Esther Linkage: As an ester, this compound might be involved in processes such as prodrug behavior, where it could be transformed into a more active form within the body.

Potential Applications

This compound may have potential applications in:

  1. Pharmaceutical Development: Its structural similarities to known drugs can lead to the design of new therapeutics.
  2. Biological Research: Can serve as a tool in studies focused on receptor interactions due to its functional groups.
  3. Cosmetic Chemistry: Possibly used in formulations aimed at skin hydration and protection.

Scientific Implications

This compound serves as a reminder of the intricate design of chemical entities that can mimic or enhance biological functions. As the renowned chemist, Linus Pauling once stated, "The best way to have a good idea is to have lots of ideas." In this spirit, compounds like [3-(dimethylamino)-2-hydroxy-propyl] 4-(propylamino)benzoate inspire ongoing research into novel therapeutic pathways.

Overall, studying such compounds not only broadens our understanding of chemistry and biology but also paves the way for innovations that can greatly benefit various industries.

Synonyms
Hydroxycaine
Cornecain
Cornecaine
Cornecaine [WHO-DD]
3WW707377Q
3686-68-8
UNII-3WW707377Q
Benzoic acid, p-(propylamino)-, 3-(dimethylamino)-2-hydroxypropyl ester
DTXSID101043339
NS00003404
Q27258152