Skip to main content

Serotonin

ADVERTISEMENT
Identification
Molecular formula
C10H12N2O
CAS number
50-67-9
IUPAC name
3-[(dimethylamino)methyl]-1H-indol-5-amine
State
State

At room temperature, serotonin is typically found as a solid.

Melting point (Celsius)
167.00
Melting point (Kelvin)
440.15
Boiling point (Celsius)
392.60
Boiling point (Kelvin)
665.80
General information
Molecular weight
176.22g/mol
Molar mass
176.2180g/mol
Density
1.2000g/cm3
Appearence

Serotonin appears as a white to off-white crystalline powder. Its form can vary depending on its degree of hydration and how it has been processed for storage or transport.

Comment on solubility

Solubility of 3-[(dimethylamino)methyl]-1H-indol-5-amine

The solubility of 3-[(dimethylamino)methyl]-1H-indol-5-amine can be influenced by various factors including its molecular structure, temperature, and the solvent used. This compound exhibits moderate solubility in polar solvents due to the presence of the dimethylamino group, which can engage in hydrogen bonding and facilitate interactions with water molecules.

Key Points on Solubility:

  • Polar Solvents: The compound is likely to be more soluble in polar solvents like water or methanol.
  • Temperature Effects: As temperature increases, solubility may improve, supporting higher dissolution rates.
  • Functional Groups: The presence of the -NH and -N(CH3) groups can enhance solubility due to their ability to form hydrogen bonds.

Therefore, when considering the solubility of 3-[(dimethylamino)methyl]-1H-indol-5-amine, it is essential to account for the interaction capabilities of its functional groups with the solvent environment. The structural characteristics suggest that this compound can dissolve effectively in suitable polar solvents, although its exact solubility may vary with concentration and specific conditions.

Interesting facts

Interesting Facts about 3-[(dimethylamino)methyl]-1H-indol-5-amine

3-[(Dimethylamino)methyl]-1H-indol-5-amine, commonly referenced in scientific literature, is a fascinating compound due to its unique properties and applications. Here are some engaging facts about this compound:

  • Structure and Functionality: The compound features an indole core, which is a significant structure in numerous natural products and pharmaceuticals. The presence of a dimethylamino group grants it intriguing biological properties.
  • Biological Relevance: Many indole derivatives exhibit promising pharmacological activities. This compound, in particular, has garnered attention for its potential use in developing new therapeutic agents, particularly in the realm of oncology and neurobiology.
  • Research Applications: Scientists are actively researching this compound for its potential role as a substrate or intermediate in synthetic organic chemistry. Its ability to serve as a building block for more complex molecules showcases the versatility of indole derivatives.
  • Interaction with Receptors: Compounds similar to 3-[(dimethylamino)methyl]-1H-indol-5-amine have been studied for their interaction with various neurotransmitter receptors, which could lead to new insights in treating mood disorders and cognitive enhancements.
  • Skin Penetration: The chemical structure suggests favorable lipophilicity, making it a candidate for transdermal drug delivery systems. As such, ongoing research investigates how effectively this compound can permeate biological membranes.

In conclusion, the study of 3-[(dimethylamino)methyl]-1H-indol-5-amine is not only valuable for understanding its chemical properties but also highlights its potential impact in medicinal chemistry and pharmacology. The ongoing exploration of indole derivatives like this one could pave the way for innovative therapies in the near future, making it a compound of significant interest in the scientific community.

Synonyms
5-Aminogramine
3414-74-2
5-Graminylamine
INDOLE, 5-AMINO-3-((DIMETHYLAMINO)METHYL)-
BRN 0393962
3-((Dimethylamino)methyl)-5-indoleamine
5-Amino-3-((dimethylamino)methyl)indole
DTXSID30187737
DTXCID90110228
5-22-11-00288 (beilstein handbook reference)
3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-5-AMINE
3-((Dimethylamino)methyl)-1H-indol-5-amine
1H-Indole-3-methanamine, 5-amino-N,N-dimethyl-
AKOS005258827
FA52347
CS-0451346
3-(Dimethylaminomethyl)-5-aminoindole;3-Dimethylaminomethyl-1H-indol-5-ylamine