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Nitrofurazone

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Identification
Molecular formula
C6H6N4O4
CAS number
59-87-0
IUPAC name
3-(dimethylamino)propyl 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxylate
State
State

At room temperature, nitrofurazone is a solid. It is typically encountered in its powdered form when used in chemical or pharmaceutical applications.

Melting point (Celsius)
242.00
Melting point (Kelvin)
515.15
Boiling point (Celsius)
433.15
Boiling point (Kelvin)
706.30
General information
Molecular weight
225.14g/mol
Molar mass
225.1550g/mol
Density
1.5205g/cm3
Appearence

Nitrofurazone appears as a bright yellow crystalline powder. It is brightly colored due to its molecular structure which supports the absorption of visible light. It can also be formulated into creams and ointments for medicinal applications.

Comment on solubility

Solubility of 3-(Dimethylamino)propyl 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxylate

The solubility of 3-(dimethylamino)propyl 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxylate is a critical aspect of its chemical behavior and applicability in various fields. Understanding its solubility can lead to insights on its usage in pharmaceuticals, agrochemicals, and other applications. Here are several points to consider:

  • Polarity: This compound's structure includes both polar and non-polar functional groups, which can lead to variable solubility in different solvents. Polar solvents like water may have limited solubility due to the hydrophobic isoxazole ring.
  • Solvent Interaction: The solubility can change significantly based on the nature of the solvent. Typically, the compound may find better solubility in organic solvents such as ethyl acetate, methanol, or dichloromethane.
  • Temperature Dependency: Like many compounds, solubility may increase with temperature, which is particularly important during synthesis or application processes.
  • pH Influence: Given the presence of a carboxylate group, solubility may also be affected by the pH, where acidic conditions might enhance solubility due to protonation.

In summary, the solubility of 3-(dimethylamino)propyl 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxylate is influenced by its molecular structure, the solvent used, temperature, and pH conditions. It's essential to evaluate these factors for optimal use in various applications.

Interesting facts

Interesting Facts about 3-(Dimethylamino)propyl 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxylate

3-(Dimethylamino)propyl 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxylate is a fascinating chemical compound with various intriguing properties and applications. Here are some noteworthy points to consider:

  • Unique Structure: This compound features an isoxazole ring, which is a five-membered heterocycle containing both nitrogen and oxygen atoms. The presence of the nitro group adds to its reactivity and can influence its biological activity.
  • Biological Activity: Compounds containing isoxazole moieties are often studied for their pharmaceutical potential. This particular compound may exhibit interesting antimicrobial or anti-inflammatory properties, making it a subject of research in medicinal chemistry.
  • Dimethylamino Group: The dimethylamino group in the structure is known for enhancing the compound's ability to act as a base, potentially increasing its solubility in various formulations, which is crucial for developing effective drugs.
  • Applications in Research: The combination of different functional groups in this compound makes it appealing for use in various chemical syntheses, potentially serving as a building block for more complex molecules.
  • Environmental Considerations: Compounds with nitro groups can raise environmental concerns due to their potential toxicity. Understanding the degradation pathways and environmental impact of such compounds is crucial for chemists.

In summary, 3-(dimethylamino)propyl 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxylate is more than just a chemical entity; it represents a rich interplay of structure and activity, making it a valuable compound for scientific exploration and potential applications in medicine.

Synonyms
4-Isoxazolecarboxylic acid, 5-methyl-3-(5-nitro-2-furyl)-, 3-(dimethylamino)propyl ester
21709-27-3
BRN 1037058
DTXSID20176094
5-Methyl-3-(5-nitro-2-furyl)-4-isoxazolecarboxylic acid 3-(dimethylamino)propyl ester