Skip to main content

Neostigmine iodide

ADVERTISEMENT
Identification
Molecular formula
C12H19N2O2
CAS number
148-47-8
IUPAC name
[3-(dimethylcarbamoyloxy)phenyl]-trimethyl-ammonium;iodide
State
State

At room temperature, neostigmine iodide is in a solid state. It is stable under normal conditions, provided it is kept in a suitable container away from excessive light and moisture. The compound is hygroscopic, meaning it can absorb moisture from the air, which can alter its state and consistency if not stored properly.

Melting point (Celsius)
176.00
Melting point (Kelvin)
449.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
319.21g/mol
Molar mass
319.2050g/mol
Density
1.4245g/cm3
Appearence

Neostigmine iodide appears as a white or off-white crystalline powder. It is typically odorless and has a bitter taste. The crystals are often fine and can vary slightly in granularity depending on preparation techniques.

Comment on solubility

Solubility of [3-(dimethylcarbamoyloxy)phenyl]-trimethyl-ammonium;iodide

The solubility of [3-(dimethylcarbamoyloxy)phenyl]-trimethyl-ammonium;iodide (also known as a quaternary ammonium compound) can be quite intriguing. The following factors often influence its solubility:

  • Ionic Nature: As a salt formed from a quaternary ammonium ion and iodide, this compound may exhibit high solubility in polar solvents such as water, due to the ionic nature of the iodide.
  • Hydrophilicity: The presence of the dimethylcarbamoyloxy group contributes to the overall polarity of the molecule, enhancing its ability to dissolve in water.
  • Temperature: Like many chemical compounds, solubility can vary with temperature changes. Typically, increased temperatures result in higher solubility.
  • Concentration Effects: In concentrated solutions, there can be ionic interactions that might lead to precipitation or reduced solubility.

In summary, the solubility of [3-(dimethylcarbamoyloxy)phenyl]-trimethyl-ammonium;iodide is likely to be high in polar solvents, primarily due to its ionic character and the polar functional group present. Its practical solubility characteristics may vary with environmental conditions, making it an interesting subject for further study.

Interesting facts

Interesting Facts about 3-(Dimethylcarbamoyloxy)phenyl-trimethyl-ammonium iodide

This compound, commonly referred to as a quaternary ammonium salt, exhibits a fascinating blend of organic chemistry and biochemistry. Here are some noteworthy aspects:

  • Quaternary Ammonium Compounds: These compounds are characterized by the presence of a positively charged nitrogen atom bound to four organic groups. This unique feature often imparts antimicrobial properties to such compounds, making them valuable in various applications.
  • Pharmaceutical Applications: 3-(Dimethylcarbamoyloxy)phenyl-trimethyl-ammonium iodide holds potential in medicinal chemistry due to its structural similarity to known pharmaceuticals. This opens doors for its use in drug design and development.
  • Solubility Enhancer: The quaternary ammonium structure often contributes to improved solubility of the compound in biological systems, facilitating better absorption and efficacy of therapeutic agents.
  • Functionality: Its activity as a surfactant makes it a significant component in formulations aimed at enhancing drug delivery systems or as an additive in cleaning agents.
  • Research Interest: Scientists are continually studying these types of compounds for their potential applications in areas such as gene delivery systems, which can transform the approach to genetic therapy.

As noted by chemists, "The utility of quaternary ammonium compounds in a variety of sectors, from healthcare to consumer goods, underscores the versatility found in organic chemistry." The continuing research into the applications and mechanisms of 3-(dimethylcarbamoyloxy)phenyl-trimethyl-ammonium iodide only highlights the exciting frontier that lies at the intersection of chemistry and health.

Synonyms
Neostigmine iodide
1212-37-9
Ammonium, (3-(dimethylcarbamoyloxy)phenyl)trimethyl-, iodide
1212-37-9 (iodide)
[3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium;iodide
3-((dimethylcarbamoyl)oxy)-N,N,N-trimethylbenzenaminium iodide
Benzenaminium, 3-[[(dimethylamino)carbonyl]oxy]-N,N,N-trimethyl-, iodide (1:1)
SB-24
TL-1321
Carbamic acid, dimethyl-, m-(trimethylammonio)phenyl ester, iodide
AMMONIUM, (m-HYDROXYPHENYL)TRIMETHYL-, IODIDE, DIMETHYLCARBAMATE
Carbamic acid, N,N-dimethyl-, 3-dimethylaminophenyl ester, methiodide
SCHEMBL20425365
DTXSID30923713
AKOS040753243
Benzenaminium, 3-(((dimethylamino)carbonyl)oxy)-N,N,N-trimethyl-, iodide
3-[(dimethylcarbamoyl)oxy]-N,N,N-trimethylanilinium iodide