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Ethyl 3-hydroxyphthalide

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Identification
Molecular formula
C10H10O3
CAS number
37554-48-4
IUPAC name
3-ethoxy-3H-isobenzofuran-1-one
State
State

At room temperature, 3-ethoxy-3H-isobenzofuran-1-one is typically found in a liquid state due to its relatively low melting point. Depending on ambient conditions, it can also form a crystalline solid.

Melting point (Celsius)
25.00
Melting point (Kelvin)
298.15
Boiling point (Celsius)
278.00
Boiling point (Kelvin)
551.15
General information
Molecular weight
178.18g/mol
Molar mass
178.1840g/mol
Density
0.7890g/cm3
Appearence

3-Ethoxy-3H-isobenzofuran-1-one typically appears as a colorless to pale yellow liquid. It may also be encountered as a crystalline solid, depending on the conditions. The compound can have a characteristic odor, which is common with many organic esters.

Comment on solubility

Solubility of 3-ethoxy-3H-isobenzofuran-1-one

3-ethoxy-3H-isobenzofuran-1-one, with its intriguing molecular structure, presents interesting considerations regarding its solubility.

Generally, the solubility of a compound like 3-ethoxy-3H-isobenzofuran-1-one can be influenced by several factors, including:

  • Polarity: The presence of the ethoxy group contributes to its polarity, which may enhance solubility in polar solvents.
  • Hydrogen Bonding: Compounds with functionalities capable of hydrogen bonding typically exhibit higher solubility in polar solvents.
  • Size of the Molecule: Larger molecules may have reduced solubility in some solvents due to steric hindrance.

In practical terms, 3-ethoxy-3H-isobenzofuran-1-one is expected to be moderately soluble in organic solvents like ethanol and dimethyl sulfoxide (DMSO), but may display limited solubility in water due to its hydrophobic hydrocarbon regions.

As described, the exact solubility can vary based on specific conditions, including temperature and concentration. For a more precise understanding, experimental measurements in various solvents are typically recommended. Remember, as the old saying goes, “Like dissolves like,” which emphasizes the compatibility of solute and solvent in determining solubility.

Interesting facts

Interesting Facts About 3-Ethoxy-3H-Isobenzofuran-1-one

3-Ethoxy-3H-isobenzofuran-1-one, also known as a synthetic organic compound, is a notable member of the isobenzofuran family. Its unique structure and properties make it of considerable interest in various fields of research. Here are some intriguing aspects:

  • Structural Significance: This compound features a fused ring system that is characteristic of isobenzofuran derivatives, imparting it with unique chemical reactivity and stability.
  • Synthetic Applications: 3-Ethoxy-3H-isobenzofuran-1-one serves as a valuable intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its versatility allows for modifications that lead to a variety of functional compounds.
  • Biological Activity: Compounds related to isobenzofuran have been studied for their biological activities. While specific studies on this compound are limited, similar derivatives have shown potential in areas such as anti-inflammatory, antimicrobial, and anticancer properties.
  • Chemical Reactivity: The presence of the ethoxy group in this compound influences its reactivity, allowing for a range of substitution reactions that can enhance its utility in further chemical transformations.
  • Research Interest: As chemists continue to explore the potential of isobenzofuran derivatives, 3-ethoxy-3H-isobenzofuran-1-one may offer pathways for discovering new materials and compounds with enhanced properties.

As a compound gaining interest in both academic and industrial settings, 3-ethoxy-3H-isobenzofuran-1-one demonstrates the fascinating interplay between structure and function in organic chemistry. Researchers are encouraged to delve deeper into its properties and potentials, as studies in this area are likely to yield promising advancements.

Synonyms
Phthalide, 3-ethoxy-
16824-02-5
3-ETHOXY-1(3H)-ISOBENZOFURANONE
3-ethoxy-3H-2-benzofuran-1-one
1(3H)-Isobenzofuranone, 3-ethoxy-
3-Ethoxyphthalide
3-Ethoxyisobenzofuran-1(3H)-one
NSC60055
SCHEMBL9538694
SCHEMBL13302911
SCHEMBL30408659
VCBNFFOSUGMASJ-UHFFFAOYSA-N
DTXSID501303460
3-Ethoxy-2-benzofuran-1(3H)-one
NSC 60055
NSC-60055
NSC132303
AKOS024335816
3-Ethoxy-2-benzofuran-1(3H)-one #
NSC 132303
NSC-132303