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Phenacetin

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Identification
Molecular formula
C10H13NO3
CAS number
62-44-2
IUPAC name
3-ethoxy-N,N-diethyl-4-hydroxy-benzamide
State
State

At room temperature, phenacetin is in a solid state. It is stable under normal conditions, but it should be handled carefully to avoid inhalation or ingestion as it can be harmful to health.

Melting point (Celsius)
134.50
Melting point (Kelvin)
407.65
Boiling point (Celsius)
515.00
Boiling point (Kelvin)
788.15
General information
Molecular weight
179.22g/mol
Molar mass
179.2160g/mol
Density
1.0995g/cm3
Appearence

Phenacetin appears as a white, crystalline powder or in crystalline solid form. It typically has a pearly luster and is odorless. The compound does not have a distinct color and is usually translucent or slightly opaque, resembling common organic crystalline substances.

Comment on solubility

Solubility of 3-ethoxy-N,N-diethyl-4-hydroxy-benzamide

3-ethoxy-N,N-diethyl-4-hydroxy-benzamide is a compound exhibiting unique solubility characteristics influenced by its molecular structure. Understanding the solubility of this compound is essential for its applications in various fields.

Key Points About Solubility:

  • Polarity: The presence of hydroxy (-OH) groups enhances the compound's polarity, making it more soluble in polar solvents such as water and alcohols.
  • Nonpolar Interactions: The ethoxy and diethyl groups contribute to the compound's ability to dissolve in nonpolar organic solvents like benzene or hexane.
  • Temperature Effects: Solubility can significantly vary with temperature; generally, higher temperatures may increase solubility in most solvents.
  • pH Influence: The ionization of the hydroxyl group can alter its solubility in aqueous solutions depending on the pH, which may lead to increased solubility at higher pH levels.

In summary, 3-ethoxy-N,N-diethyl-4-hydroxy-benzamide demonstrates versatile solubility properties, leading to its potential use in a variety of solvent systems. Exploring these solubility dynamics allows for optimized applications in pharmaceuticals, agriculture, and chemical synthesis.

Interesting facts

Interesting Facts about 3-ethoxy-N,N-diethyl-4-hydroxy-benzamide

3-ethoxy-N,N-diethyl-4-hydroxy-benzamide is a fascinating compound, often explored in the realms of medicinal chemistry and pharmacology. Known for its potential biological activities, this compound has caught the attention of researchers for several reasons:

  • Structural Significance: The structure of 3-ethoxy-N,N-diethyl-4-hydroxy-benzamide features an ethoxy group and a hydroxyl group, which can significantly influence its reactivity and interaction with biological systems.
  • Pharmacological Potential: Compounds with similar structural motifs have been studied for their anti-inflammatory and analgesic properties, making this compound a candidate for further investigation in medicinal applications.
  • Research Applications: This compound’s unique structure allows it to be a topic of interest in drug design, especially for targeting specific receptor sites in the body.
  • Derivative Studies: Chemists often explore derivatives of this compound to enhance efficacy or reduce side effects, highlighting the importance of substituents in drug activity.

As one researcher notes, “The world of benzamide derivatives is rich with possibilities, where every modification can lead to discovering new therapeutic avenues.” This emphasizes the compound's role in the broader context of drug development and its potential impact on healthcare.

In summary, 3-ethoxy-N,N-diethyl-4-hydroxy-benzamide presents exciting opportunities for exploration in both synthetic chemistry and biological applications. Its unique chemical structure and potential benefits underline the importance of continued research in this area.

Synonyms
3-Ethoxy-N,N-diethyl-4-hydroxybenzamide
Anacardiol
3-Ethoxy-4-hydroxy-diethylbenzamide
EINECS 237-669-5
Benzamide, N,N-diethyl-3-ethoxy-4-hydroxy-
BRN 2844455
4-Hydroxy-3-ethoxy-benzoic acid diethylamide
Diethylamide of 3-ethoxy-4-hydroxy-benzoic acid
DTXSID40160854
4-10-00-01483 (Beilstein Handbook Reference)
DTXCID4083345
237-669-5
13898-68-5
DEHB
SCHEMBL309382
SCHEMBL29396485
CSGBRIWXMBIKEM-UHFFFAOYSA-N
DA-10861
NS00024496