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Coumachlor

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Identification
Molecular formula
C14H10ClNO4
CAS number
1470-53-1
IUPAC name
3-ethoxycarbonyl-2-oxo-chromene-6-carboxylic acid
State
State

At room temperature, Coumachlor is in a solid state, appearing as a pale yellow powder.

Melting point (Celsius)
185.00
Melting point (Kelvin)
458.15
Boiling point (Celsius)
451.80
Boiling point (Kelvin)
724.95
General information
Molecular weight
306.27g/mol
Molar mass
306.2660g/mol
Density
1.5000g/cm3
Appearence

Coumachlor appears as a pale yellow powder.

Comment on solubility

Solubility of 3-ethoxycarbonyl-2-oxo-chromene-6-carboxylic acid

The solubility of 3-ethoxycarbonyl-2-oxo-chromene-6-carboxylic acid is an essential characteristic in understanding its behavior in various solvents. This compound, which contains both a chromene structure and carboxylic acid functional group, exhibits varying solubility depending on the solvent used. Here are some key points regarding its solubility:

  • Polar Solvents: The presence of the carboxylic acid group enhances solubility in polar solvents such as water and methanol, allowing for better dissolution due to hydrogen bonding.
  • Non-Polar Solvents: In contrast, the compound may have limited solubility in non-polar solvents like hexane or toluene due to the hydrophilic nature of the acidic group.
  • pH Dependence: The solubility can also be affected by pH levels; at lower pH, the carboxylic acid tends to be protonated, making it less soluble compared to its deprotonated state at higher pH.
  • Temperature Influence: As with many organic compounds, increasing temperature generally enhances solubility in most solvents, which is vital for applications in synthesis and formulation.

In summary, the solubility of 3-ethoxycarbonyl-2-oxo-chromene-6-carboxylic acid is a nuanced interplay of structural components and environmental conditions. Understanding these solubility behaviors is crucial for successful application in chemical research and product development.

Interesting facts

Interesting Facts about 3-Ethoxycarbonyl-2-oxo-chromene-6-carboxylic Acid

The compound 3-ethoxycarbonyl-2-oxo-chromene-6-carboxylic acid is a fascinating member of the chromene family, recognized for its intriguing structural characteristics and potential applications in various fields.

1. Structural Significance

This compound exhibits a unique combination of functional groups including:

  • Carboxylic acid: Contributing to its acidic properties and reactivity.
  • Ethoxycarbonyl group: Adding to its molecular complexity and potential for further chemical modifications.
  • Keto group: Enhancing its ability to participate in tautomeric transformations.

2. Biological Relevance

Compounds within the chromene class, such as this one, often display a variety of biological activities, including:

  • Antioxidant properties: Implicated in combating oxidative stress.
  • Anti-inflammatory effects: Potentially useful in therapeutic applications.
  • Antimicrobial activity: Effective against a range of bacterial strains.

3. Synthetic Versatility

The synthesis of 3-ethoxycarbonyl-2-oxo-chromene-6-carboxylic acid often involves elegant multi-step reactions. Strategies may include:

  • Condensation reactions: Essential for forming the chromene skeleton.
  • Substitution reactions: Key for introducing functional groups like ethoxycarbonyl and carboxylic acid.

4. Applications in Chemistry

Due to its structural attributes, this compound has potential applications in:

  • Organic synthesis: As an intermediate in the preparation of more complex molecules.
  • Material science: Potential for developing new materials with desirable properties.

In summary, 3-ethoxycarbonyl-2-oxo-chromene-6-carboxylic acid exemplifies the interplay of structure and function in chemical compounds, making it an appealing subject for further study in both academic research and practical applications.

Synonyms
3-Carbethoxy-6-carboxycoumarin
6468-72-0
BRN 1292162
2-Oxo-2H-1-benzopyran-3,6-dicarboxylic acid 3-ethyl ester
SC-351
DTXSID50214973
2H-1-BENZOPYRAN-3,6-DICARBOXYLIC ACID, 2-OXO-, 3-ETHYL ESTER
DTXCID80137464
5-18-08-00673 (beilstein handbook reference)
3-ethoxycarbonyl-2-oxochromene-6-carboxylic acid