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Ethyl N-phenylcarbamate and Methyl N-(m-tolyl)carbamate

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Identification
Molecular formula
C10H11NO3
CAS number
null
IUPAC name
[3-(ethoxycarbonylamino)phenyl] N-phenylcarbamate;[3-(methoxycarbonylamino)phenyl] N-(m-tolyl)carbamate
State
State

At room temperature, the compounds are in a solid crystalline state.

Melting point (Celsius)
80.00
Melting point (Kelvin)
353.00
Boiling point (Celsius)
301.00
Boiling point (Kelvin)
574.00
General information
Molecular weight
271.32g/mol
Molar mass
271.3150g/mol
Density
1.3000g/cm3
Appearence

Both ethyl N-phenylcarbamate and methyl N-(m-tolyl)carbamate generally appear as white crystalline solids.

Comment on solubility

Solubility Characteristics of the Compound

The solubility of [3-(ethoxycarbonylamino)phenyl] N-phenylcarbamate and [3-(methoxycarbonylamino)phenyl] N-(m-tolyl)carbamate can vary due to the presence of different functional groups. Understanding their solubility is crucial for various applications, including pharmaceutical formulations and chemical reactions.

Key Factors Influencing Solubility:

  • Polarity: The polar groups in the compounds, such as the carbamate functionality, may enhance solubility in polar solvents like water.
  • Hydrophobic Interactions: The alkyl side chains (ethoxy and methoxy groups) can create mixed solubility behavior, leading to lower solubility in highly polar solvents.
  • Hydrogen Bonding: The potential for hydrogen bonding with solvents can significantly increase the solubility of these compounds.

As a general observation, carbamates tend to be more soluble in organic solvents but can also exhibit considerable solubility in alcohols and other protic solvents due to their structure.

Solubility Insights:

  • Both compounds are likely to show moderate solubility in aqueous media, particularly under acidic conditions.
  • In organic solvents such as methanol or ethanol, solubility may be significantly enhanced due to favorable interactions.
  • Solubility can be influenced by the temperature, where increasing temperature generally leads to increased solubility for solid compounds.

In conclusion, while both compounds feature functionalities that can facilitate solubility in various environments, their specific solubility will need to be evaluated experimentally to determine precise values under different conditions.

Interesting facts

Interesting Facts about [3-(ethoxycarbonylamino)phenyl] N-phenylcarbamate

[3-(ethoxycarbonylamino)phenyl] N-phenylcarbamate is a fascinating compound within the realm of organic chemistry, particularly renowned for its potential applications in medicinal chemistry. Here are some intriguing insights:

  • Pharmaceutical Applications: This compound features structures that may be instrumental in developing pharmaceutical agents. Its diverse functional groups allow for potential interactions with biological targets.
  • Mechanism of Action: Compounds like this one potentially act by modulating enzyme activity, showcasing the importance of carbamates in inhibiting enzymes within metabolic pathways.
  • Structure-Activity Relationships: The various substituents on the aromatic ring provide opportunities for scientists to explore how modifications influence biological activity, reaffirming the significance of structural design in drug development.

Safety and Handling

As with many chemical compounds, understanding its safety profile is crucial. Researchers must always refer to material safety data sheets (MSDS) for guidelines on handling and disposal.

Interesting Facts about [3-(methoxycarbonylamino)phenyl] N-(m-tolyl)carbamate

Similar to its counterpart, [3-(methoxycarbonylamino)phenyl] N-(m-tolyl)carbamate is a compound rich in chemical potential, especially in organic synthesis and pharmaceuticals. Here are some notable aspects:

  • Innovative Chemical Synthesis: This compound demonstrates the beauty of organic synthesis, where chemists can utilize various reaction pathways to create it, enhancing their skills in synthetic techniques.
  • Potential Bioactivity: The methoxy group can significantly influence the compound's lipophilicity, which is an important factor for drug-like properties and bioavailability.
  • Cyclic Analogs: There’s an ongoing interest in researching cyclic variants of carbamate compounds, which could lead to novel therapeutic agents garnered from insights gained from this compound.

Research Directions

Researchers are encouraged to further explore this compound's efficacy in vivo, opening up possibilities for future breakthroughs in drug discovery.

In summary, both compounds highlight the interplay between structure and function, ushering in innovations in medicinal chemistry and organic synthesis.

Synonyms
Betamix
8074-50-8
Betanal compact
Synbetan mix
Betanal AM 21
[3-(ethoxycarbonylamino)phenyl] N-phenylcarbamate;[3-(methoxycarbonylamino)phenyl] N-(3-methylphenyl)carbamate
Desmedipham and phenmedipham (1:1)
Phenmedipham and desmedipham (1:1)
SN 503
SR 020
Phenmedipham-EP 475 mixt.
SCHEMBL3230751
DTXSID80230585