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3-ethyl-2-(1-methyl-2-piperidyl)-1H-indole

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Identification
Molecular formula
C16H22N2
CAS number
2210-90-0
IUPAC name
3-ethyl-2-(1-methyl-2-piperidyl)-1H-indole
State
State

This compound is typically a solid at room temperature, given its relatively high melting point.

Melting point (Celsius)
78.00
Melting point (Kelvin)
351.15
Boiling point (Celsius)
342.00
Boiling point (Kelvin)
615.15
General information
Molecular weight
242.34g/mol
Molar mass
242.3440g/mol
Density
1.1500g/cm3
Appearence

This compound, a derivative of indole, typically appears as a crystalline solid. Its exact color or specific appearance details may vary depending on the purity and form in which it is prepared or available.

Comment on solubility

Solubility of 3-ethyl-2-(1-methyl-2-piperidyl)-1H-indole

Understanding the solubility of 3-ethyl-2-(1-methyl-2-piperidyl)-1H-indole is essential for various applications in chemistry and pharmaceuticals. Here are some key points regarding its solubility:

  • Solvent Interaction: The compound's solubility is influenced by its structural features, such as the indole ring and the piperidine group, which enable it to interact effectively with polar solvents.
  • Polarity: Generally, compounds containing nitrogen-containing heterocycles tend to exhibit better solubility in polar solvents due to hydrogen bonding capabilities.
  • Temperature Effects: Solubility can increase with temperature. Thus, it may be more soluble in heated solutions than in cold ones.
  • pH Dependency: The solubility might also vary with pH, particularly because of the basic nitrogen atoms, which can become protonated in acidic conditions, enhancing solubility.
  • Practical Applications: For practical applications, including drug formulation, knowing the solubility profile is crucial for ensuring adequate bioavailability.

In summary, the solubility of 3-ethyl-2-(1-methyl-2-piperidyl)-1H-indole is a complex interplay of molecular structure, solvent characteristics, temperature, and pH. A thorough understanding of these factors is essential for optimizing its use in various chemical and pharmacological contexts.

Interesting facts

Interesting Facts about 3-Ethyl-2-(1-methyl-2-piperidyl)-1H-indole

3-Ethyl-2-(1-methyl-2-piperidyl)-1H-indole is a fascinating compound that showcases the diversity of chemical structures within the indole family. Indoles, characterized by their incorporation of a fused benzene and pyrrole ring, have gained importance both in medicinal chemistry and organic synthesis.

Key Aspects of 3-Ethyl-2-(1-methyl-2-piperidyl)-1H-indole:

  • Pharmacological Potential: Indole derivatives, including this compound, have been studied for their potential pharmacological effects. These compounds are often found to exhibit activity against various biological targets, making them a playground for drug discovery.
  • Piperidine Linkage: The presence of a piperidine group adds to its structural complexity and may influence the molecule's interactions with biological systems. Piperidine moieties are known to enhance solubility and modulate receptor affinity.
  • Research Applications: This compound has potential applications in the field of neuroscience, particularly in studies related to mood regulation and anxiety, due to the known effects of indolic compounds on neurotransmitter systems.
  • Synthesis: The synthesis of such compounds can be intricate but offers numerous opportunities to explore new chemistries through various methods, including cyclization reactions and functional group modifications.

To sum it up, 3-Ethyl-2-(1-methyl-2-piperidyl)-1H-indole is not only a structurally rich compound, but it also provides insight into how diverse modifications can create molecules with unique characteristics. As research continues, it may unveil further therapeutic potentials and lead to the discovery of novel applications.

Synonyms
13994-11-1
1H-Indole, 3-ethyl-2-(1-methyl-2-piperidinyl)-
RP 7065
3-ethyl-2-(1-methylpiperidin-2-yl)-1H-indole
RP-7065
BRN 0236211
3-Ethyl-2-(1-methyl-2-piperidyl)indole
3-Ethyl-2-(N-methylpiperidyl-2')-indole
INDOLE, 3-ETHYL-2-(1-METHYL-2-PIPERIDYL)-
5-23-07-00436 (Beilstein Handbook Reference)
DTXSID90930665