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Thioflavin T

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Identification
Molecular formula
C17H19N2S2+ I-
CAS number
2390-54-7
IUPAC name
3-ethyl-2-[3-(3-ethyl-1,3-benzothiazol-3-ium-2-yl)-2-methyl-prop-2-enylidene]-1,3-benzothiazole;iodide
State
State

At room temperature, Thioflavin T is typically a solid.

Melting point (Celsius)
261.00
Melting point (Kelvin)
534.15
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
480.02g/mol
Molar mass
480.0200g/mol
Density
1.0395g/cm3
Appearence

Thioflavin T appears as a yellow crystalline powder. It is known for its bright yellow fluorescence when bound to amyloid fibrils, making it a useful tool in biochemistry for detecting and studying these fibrils.

Comment on solubility

Solubility of 3-ethyl-2-[3-(3-ethyl-1,3-benzothiazol-3-ium-2-yl)-2-methyl-prop-2-enylidene]-1,3-benzothiazole; iodide

The solubility of the compound 3-ethyl-2-[3-(3-ethyl-1,3-benzothiazol-3-ium-2-yl)-2-methyl-prop-2-enylidene]-1,3-benzothiazole; iodide is influenced by several factors due to its complex chemical structure. Here are some key points regarding its solubility:

  • Polar and Non-Polar Regions: The presence of both polar benzothiazole units and the iodide counterion may enhance solubility in polar solvents like water.
  • Solvent Interactions: The compound may exhibit better solubility in organic solvents such as ethanol or DMSO due to its hydrophobic sections.
  • Influence of Temperature: As with many organic compounds, an increase in temperature typically leads to higher solubility.
  • pH Sensitivity: If the compound has ionizable groups, changes in pH can significantly alter its solubility profile.

In conclusion, the solubility of this intricate compound is a balance between its hydrophilic and hydrophobic characteristics, making it essential to consider the environment in which it is dissolved. As the saying goes, “like dissolves like,” which perfectly captures the principle behind its solubility.

Interesting facts

Interesting Facts about 3-ethyl-2-[3-(3-ethyl-1,3-benzothiazol-3-ium-2-yl)-2-methyl-prop-2-enylidene]-1,3-benzothiazole;iodide

This intriguing compound, known for its complex structure and unique properties, is part of the larger realm of benzothiazole derivatives. Here are some fascinating insights:

  • Versatile Applications: This compound may play a role in various fields, including materials science and medicinal chemistry. Its structural features make it a candidate for research into novel dyes or biological agents.
  • Structural Complexity: The molecular architecture features multiple functional groups and ring systems, highlighting the diversity of organic compounds and the potential for unique reactivity.
  • Synthetic Pathways: The synthesis of compounds like this usually involves multi-step processes, often requiring advanced techniques in organic chemistry such as cross-coupling reactions or condensation reactions.
  • Electrochemical Properties: The presence of nitrogen and sulfur in its framework contributes to interesting electrochemical behavior, making these types of compounds valuable in the development of sensors and electronic materials.
  • Biological Activity: The benzothiazole moiety is known for its pharmacological properties, and derivatives related to it have been studied for activities such as antimicrobial and anticancer effects.

Scientists are continually exploring the implications of such compounds, emphasizing the relationship between structure and activity. It’s a great example of how subtle changes in molecular design can lead to significant differences in function and application.

Lastly, as with many benzothiazole derivatives, it's essential to consider both the potential benefits and challenges that come with their use, particularly in environmental and health-related contexts. Rigorous testing and evaluation are crucial to understanding the impact of such compounds fully.

Synonyms
3-ethyl-2-[(1E)-3-[(2E)-3-ethyl-2,3-dihydro-1,3-benzothiazol-2-ylidene]-2-methylprop-1-en-1-yl]-1,3-benzothiazol-3-ium iodide
SAEMBGFHGROQJZ-UHFFFAOYSA-M
AKOS030238818
NS00046303
3,3'-DIETHYL-9-METHYLTHIACARBOCYANINEIODIDE