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Thioflavin T

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Identification
Molecular formula
C17H19N2S2+ I-
CAS number
2390-54-7
IUPAC name
3-ethyl-2-[5-(3-ethyl-7-methyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-7-methyl-1,3-benzothiazole;iodide
State
State
Thioflavin T is typically found as a solid at room temperature.
Melting point (Celsius)
275.00
Melting point (Kelvin)
548.15
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.15
General information
Molecular weight
482.60g/mol
Molar mass
482.5960g/mol
Density
1.3497g/cm3
Appearence
Thioflavin T appears as a bright yellow crystalline powder. It is often used as a fluorescent dye and is known for its intense yellow fluorescence when bound to amyloid fibrils.
Comment on solubility

Solubility of 3-ethyl-2-[5-(3-ethyl-7-methyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-7-methyl-1,3-benzothiazole;iodide

The solubility of the compound 3-ethyl-2-[5-(3-ethyl-7-methyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-7-methyl-1,3-benzothiazole;iodide is influenced by several factors due to its complex structure. Generally, the following points can be considered:

  • Polarity: The presence of multiple functional groups within the benzothiazole rings suggests a level of polarity that may enhance solubility in polar solvents.
  • Solvent Interaction: This compound may exhibit higher solubility in dimethyl sulfoxide (DMSO), dimethylformamide (DMF), or other polar organic solvents due to its ionic iodide component.
  • Temperature Effects: Increased temperature can potentially improve solubility, allowing for better dissolution in chosen solvents.
  • Concentration Dependence: Preliminary studies may indicate that solubility is concentration-dependent, necessitating experimentation to ascertain specific limits.

It is essential to conduct empirical tests to confirm solubility under varying conditions, as theoretical estimates may not always reflect real-world behavior. As stated, “The solubility of compounds can be as much an art as it is a science,” reflecting the complexities of chemical interactions.

Interesting facts

Fascinating Insights into 3-ethyl-2-[5-(3-ethyl-7-methyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-7-methyl-1,3-benzothiazole;iodide

The compound known as 3-ethyl-2-[5-(3-ethyl-7-methyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-7-methyl-1,3-benzothiazole;iodide is a member of the benzothiazole class, a group of compounds renowned for their diverse applications in material science and medicinal chemistry. Here are some intriguing facts about this compound:

  • Benzothiazole Derivatives: Benzothiazoles like this one often exhibit antimicrobial properties and are studied for potential applications in drug development.
  • Structural Complexity: The presence of multiple functional groups, such as the ethyl and methyl substituents, contributes to its unique chemical behavior and enhances its solubility in organic solvents.
  • Applications in Fluorescent Dyes: Compounds related to benzothiazoles are frequently utilized in creating fluorescent dyes, making them valuable in biological imaging and sensor technology.
  • Iodide Ion Role: The iodide component of the compound serves as a counterion, potentially influencing the compound's solubility and stability, and permitting various applications in organic synthesis.

Moreover, the compound's intricate structure highlights the beauty and complexity of organic chemistry, showcasing the importance of interdisciplinary approaches in advancing scientific knowledge. As researchers continue to investigate the properties of benzothiazole derivatives, compounds like this one hold great promise for future innovations in both pharmaceuticals and materials science.

Synonyms
3-Ethyl-2-[5-(3-ethyl-7-methyl-1,3-benzothiazol-2(3H)-ylidene)penta-1,3-dien-1-yl]-7-methyl-1,3-benzothiazol-3-ium iodide
DTXSID00907767