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3-Ethyl-5-methylphenol

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Identification
Molecular formula
C9H12O
CAS number
621-27-2
IUPAC name
3-ethyl-5-methyl-phenol
State
State

3-Ethyl-5-methylphenol is a liquid at room temperature. Its clear appearance and potential colorlessness make it identifiable, especially when compared with other liquid phenolic compounds.

Melting point (Celsius)
14.00
Melting point (Kelvin)
287.15
Boiling point (Celsius)
230.00
Boiling point (Kelvin)
503.15
General information
Molecular weight
136.19g/mol
Molar mass
136.1910g/mol
Density
0.9745g/cm3
Appearence

3-Ethyl-5-methylphenol typically appears as a clear, colorless to pale yellow liquid. It may possess a characteristic phenolic odor, which can be intense and sharp. The compound is often utilized in various chemical syntheses and may be available in technical grade due to its applications in both laboratory and industrial settings.

Comment on solubility

Solubility of 3-Ethyl-5-methyl-phenol

3-Ethyl-5-methyl-phenol, also known as ethyl m-cresol, exhibits interesting solubility characteristics due to its molecular structure. Here are some key points regarding its solubility:

  • Solvent Interactions: This compound is generally soluble in organic solvents such as ethanol, acetone, and chloroform.
  • Water Solubility: 3-Ethyl-5-methyl-phenol has very **limited solubility** in water. This is primarily due to the hydrophobic nature of its aromatic character, which makes it less favorable for interaction with polar water molecules.
  • Temperature Effects: Solubility can increase with temperature, which may promote the dissolution of this compound in certain organic solvents.
  • Biodistribution: Its low water solubility might affect its distribution in biological systems, which is important for understanding its potential toxicological effects.

In summary, while 3-ethyl-5-methyl-phenol is more soluble in organic solvents, its limited solubility in water emphasizes the importance of considering solvent choice in various applications such as synthesis and analysis.

Interesting facts

Interesting Facts about 3-Ethyl-5-methyl-phenol

3-Ethyl-5-methyl-phenol, also known in some circles as nonylphenol, is a fascinating organic compound belonging to the family of phenols. Here are some intriguing insights about this compound:

  • Structure and Isomerism: The compound features a phenolic structure, which means it consists of a benzene ring connected to a hydroxyl group (–OH). It possesses unique isomeric variations, with the position of the ethyl and methyl groups influencing its chemical properties significantly.
  • Applications: 3-Ethyl-5-methyl-phenol is primarily used in the manufacturing of surfactants, which are crucial in detergents and cleaning products. This compound also finds utility in the production of antioxidants and corrosion inhibitors.
  • Biological Activity: It has been studied for its biological activity, particularly in its potential as a hormone disruptor. These characteristics raise important environmental and health considerations, leading researchers to explore its effects on aquatic life.
  • Synthesis Methods: Common synthesis methods involve the alkylation of phenol derivatives, followed by specific reactions that allow the introduction of ethyl and methyl groups. Understanding these processes can provide significant insights into organic synthesis.
  • Environmental Concerns: The compound is part of discussions surrounding endocrine disruptors, which can disrupt hormonal systems in wildlife. This has spurred regulatory interest and encouraged research into alternatives that are safer for both humans and the environment.

In summary, 3-ethyl-5-methyl-phenol stands out not only for its industrial applications but also for its implications in environmental health. As researchers continue to investigate its properties and effects, this compound serves as a reminder of the balance needed between utility and safety in chemistry.

Synonyms
3-ETHYL-5-METHYLPHENOL
698-71-5
m-Cresol, 5-ethyl-
3-Methyl-5-ethylphenol
Phenol, 3-ethyl-5-methyl-
1-Hydroxy-3-methyl-5-ethylbenzene
UNII-ZV1NMG73ZT
ZV1NMG73ZT
NSC 8885
NSC-8885
EINECS 211-818-4
NSC 62673
NSC-62673
AI3-24210
DTXSID60220101
m-Cresol, 5-ethyl-(8CI)
DTXCID20142592
Phenol, 3-ethyl-5-methyl-(9CI)
211-818-4
xtchlxablzqnnn-uhfffaoysa-n
5-Ethyl-m-cresol
3-ethyl-5-methyl-phenol
5-Ethyl-3-methylphenol
5-Ethyl-m-cresol, 8CI
SCHEMBL911575
m-Cresol, 5-ethyl- (8CI)
NSC8885
CHEBI:196443
NSC62673
Phenol, 3-ethyl-5-methyl- (9CI)
AKOS006273528
AS-57682
DB-074229
CS-0186818
NS00036977
D84187
Q27295901