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3-Fluorobenzoic acid

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Identification
Molecular formula
C7H5FO2
CAS number
455-38-9
IUPAC name
3-fluorobenzoic acid
State
State

3-Fluorobenzoic acid is typically found in a solid state at room temperature.

Melting point (Celsius)
124.00
Melting point (Kelvin)
397.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
140.11g/mol
Molar mass
140.1140g/mol
Density
1.4182g/cm3
Appearence

3-Fluorobenzoic acid is a white crystalline powder. It is often used in organic synthesis and has a distinctive crystalline appearance.

Comment on solubility

Solubility of 3-fluorobenzoic acid

3-fluorobenzoic acid, with the chemical formula C7H5F O2, exhibits interesting solubility properties that can be influenced by various factors. Its solubility in water is relatively limited due to the presence of the hydrophobic aromatic ring, which tends to resist dissolution in polar solvents. However, the carboxylic acid functional group (-COOH) enhances its ability to engage in hydrogen bonding with water, attributed to the following points:

  • Moderate Water Solubility: 3-fluorobenzoic acid has moderate solubility in water, ranging from approximately 3 to 6 g/L at room temperature.
  • Solvent Interaction: It dissolves more readily in organic solvents such as ethanol and acetone, where the interactions with nonpolar groups are more favorable.
  • Temperature Effects: As with many compounds, increasing temperature can improve solubility in water, making it more amenable to dissolution in warm solutions.

In summary, while 3-fluorobenzoic acid is not highly soluble in water, its moderate solubility combined with better compatibility in organic solvents underscores its versatility in various chemical processes. Thus, it serves as a useful intermediate in organic synthesis, especially when an understanding of solubility properties is crucial for reaction setup.

Interesting facts

Interesting Facts about 3-Fluorobenzoic Acid

3-Fluorobenzoic acid, an important member of the benzoic acid family, holds a unique position in organic chemistry due to its distinctive properties and applications. Here are some noteworthy aspects:

  • Fluorine Influence: The presence of the fluorine atom introduces significant polarity and electronic effects, altering the compound's behavior in various reactions.
  • Industrial Relevance: This compound is often utilized in the synthesis of pharmaceuticals, dyes, and agrochemicals, showcasing its versatility in various chemical industries.
  • Biological Applications: Due to its structural similarity to other benzoic acids, 3-fluorobenzoic acid can serve as a building block in the design of biologically active molecules.
  • Research Focus: Scientists are increasingly exploring its use in drug discovery and development, where minor modifications can lead to compounds with enhanced therapeutic effects.
  • Environmental Considerations: While it is valuable, researchers keep an eye on the environmental impact of fluorinated compounds, advocating for sustainable practices in their synthesis and application.

As you delve into the chemistry of 3-fluorobenzoic acid, keep in mind the balance between innovation and responsibility. The compound’s ability to impact both industrial processes and biological research underlines its significance in modern chemistry.

In the words of a prominent chemist, “The small changes we make to molecular structures often lead to profound implications in the world of science.” This holds true for 3-fluorobenzoic acid, reminding us of the potential hidden in seemingly simple compounds.

Synonyms
3-FLUOROBENZOIC ACID
455-38-9
m-Fluorobenzoic acid
Benzoic acid, 3-fluoro-
Benzoic acid, m-fluoro-
meta-Fluorobenzoic acid
MFCD00002489
ELG54JFF34
CHEBI:20021
3-Fluoro-Benzoic Acid
EINECS 207-248-0
NSC 10320
NSC-10320
DTXSID4060020
NSC176125
NSC-176125
m-Fluorobenzoic Acid; NSC 10320; NSC 176125;
mFluorobenzoic acid
Benzoic acid, mfluoro
Benzoic acid, 3fluoro
UNII-ELG54JFF34
SCHEMBL28396
3-Fluorobenzoic acid, 97%
Benzoic acid, mfluoro (8CI)
CHEMBL302365
Benzoic acid, m-fluoro-(8CI)
DTXCID9040429
NSC10320
AC7508
STK498748
AKOS000119589
BS-3795
CS-W016469
HY-W015753
SY002150
DB-024078
F0158
NS00043529
EN300-20215
C02364
AE-562/40187179
Q18472686
F2191-0061
Z104477304
207-248-0