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(3-Fluorophenyl)urea

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Identification
Molecular formula
C7H7FN2O
CAS number
21911-62-2
IUPAC name
(3-fluorophenyl)urea
State
State
In its typical state, (3-Fluorophenyl)urea is a solid. It is usually handled in its crystalline powder form.
Melting point (Celsius)
182.00
Melting point (Kelvin)
455.00
Boiling point (Celsius)
357.00
Boiling point (Kelvin)
630.00
General information
Molecular weight
154.14g/mol
Molar mass
154.1430g/mol
Density
1.4030g/cm3
Appearence

(3-Fluorophenyl)urea is a crystalline solid. It appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of (3-fluorophenyl)urea

The solubility of (3-fluorophenyl)urea in various solvents is an intriguing subject. This compound exhibits some unique characteristics that influence its dissolving properties:

  • Polarity: The presence of the fluorine atom increases the polarity of the phenyl ring, which can enhance its solubility in polar solvents.
  • Hydrogen Bonding: The urea functional group can participate in hydrogen bonding, making (3-fluorophenyl)urea more soluble in water compared to non-polar solvents.
  • Common Solvents: It tends to dissolve well in solvents such as:
    • Water
    • Dimethyl sulfoxide (DMSO)
    • Alcohols
  • Limited Solubility: In contrast, (3-fluorophenyl)urea is less soluble in non-polar organic solvents such as hexane or toluene.

In summary, the solubility of (3-fluorophenyl)urea is significantly influenced by its functional groups and molecular structure. For those exploring its applications, understanding these solubility properties can be quite beneficial.

Interesting facts

Interesting Facts about (3-fluorophenyl)urea

(3-fluorophenyl)urea is a fascinating compound that belongs to the family of ureas, which are organic compounds known for their versatility in biological and chemical systems. Here are some interesting aspects of this compound:

  • Synthesis and Reactivity: This compound can be synthesized through various methods, including the reaction of 3-fluorophenol with isocyanates. Its reactivity allows for potential modifications that can lead to new derivatives, which makes it a compound of interest in organic synthesis.
  • Biological Importance: Ureas like (3-fluorophenyl)urea can exhibit pharmaceutical properties. Researchers are exploring compounds in this category for their ability to act as drug candidates in treating various diseases, particularly in medicinal chemistry.
  • Fluorination Effects: The presence of the fluorine atom in the 3-position of the phenyl ring can significantly influence the compound's chemical behavior. For example, fluorine can enhance metabolic stability and lipophilicity, potentially leading to better drug-like properties.
  • Applications in Agriculture: Compounds with urea functionalities are often utilized as herbicides, insecticides, or fungicides. The derivatives of (3-fluorophenyl)urea are being studied for similar applications in modern agricultural practices.

As a scientist or chemistry student, understanding compounds like (3-fluorophenyl)urea opens up numerous avenues for research. Its interesting blend of structure and reactivity not only contributes to its chemical uniqueness but also highlights the potential for innovative applications across various fields.


Synonyms
3-FLUOROPHENYLUREA
820-818-9
770-19-4
(3-fluorophenyl)urea
1-(3-Fluorophenyl)urea
Urea, (m-fluorophenyl)-
M-fluorophenylurea
(m-Fluorophenyl)urea
MFCD03094128
N-3-fluorophenyl urea
N'-(3-fluorophenyl)urea
SCHEMBL167713
DTXSID40227815
OLVWURSZQFCLCZ-UHFFFAOYSA-N
AKOS000143297
PS-8874