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3-Formylindole-5-carbonitrile

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Identification
Molecular formula
C10H6N2O
CAS number
39247-85-3
IUPAC name
3-formyl-1H-indole-5-carbonitrile
State
State

At room temperature, 3-Formylindole-5-carbonitrile is a solid compound.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
355.00
Boiling point (Kelvin)
628.15
General information
Molecular weight
170.16g/mol
Molar mass
170.1630g/mol
Density
1.3100g/cm3
Appearence

3-Formylindole-5-carbonitrile appears as a pale yellow to beige crystalline powder.

Comment on solubility

Solubility of 3-formyl-1H-indole-5-carbonitrile

The solubility of 3-formyl-1H-indole-5-carbonitrile can be categorized based on its structural features and functional groups, which often influence its interaction with solvents. Generally, the presence of polar functional groups, such as the formyl (-CHO) and cyano (-CN) groups, suggests that this compound may exhibit varying degrees of solubility in different solvents.

Key Factors Affecting Solubility:

  • Polarity: The polar nature of the formyl group may enhance solubility in polar solvents like water and alcohols.
  • Hydrogen Bonding: The capacity for hydrogen bonding due to the formyl group can further increase solubility in polar media.
  • Solvent Types: Non-polar solvents may show lower solubility due to the lack of interaction with the significant polar features of the compound.

As a general trend, compounds containing both polar and non-polar characteristics tend to have better solubility in mixed solvent systems. It is essential to consider that factors such as temperature can significantly affect solubility as well.

In summary, while specific solubility data might vary, 3-formyl-1H-indole-5-carbonitrile is expected to show reasonable solubility in polar solvents owing to its polar functional groups, but may face challenges in non-polar environments.

Interesting facts

Interesting Facts about 3-formyl-1H-indole-5-carbonitrile

3-formyl-1H-indole-5-carbonitrile is a fascinating compound that belongs to the indole family, which is renowned for its diverse biological activities and aromatic properties. Here are some engaging insights about this compound:

  • Indole Derivatives: The indole framework is a prominent structure in medicinal chemistry. It often serves as a building block for synthesizing pharmaceuticals and biologically active molecules.
  • Unique Functional Groups: The presence of both formyl and carbonitrile groups in 3-formyl-1H-indole-5-carbonitrile enhances its reactivity and potential applications in organic synthesis.
  • Biological Activities: Compounds derived from indoles have been reported to exhibit a wide range of biological properties, including anticancer, antimicrobial, and anti-inflammatory effects. This makes them significant in drug discovery.
  • Research Potential: The unique structure of 3-formyl-1H-indole-5-carbonitrile makes it a promising candidate for further research in organic and medicinal chemistry, especially for developing new therapeutic agents.
  • Versatile Reactivity: The compound's reactive carbonyl and nitrile groups allow for various chemical transformations, making it an attractive target for synthetic chemists aiming to develop novel materials.

In conclusion, 3-formyl-1H-indole-5-carbonitrile not only stands out due to its intriguing structure but also offers vast potential for future scientific exploration. As researchers continue to investigate its properties, this compound could lead to breakthroughs in various fields, particularly in the development of new drugs.

Synonyms
3-formyl-1H-indole-5-carbonitrile
626-842-4
17380-18-6
5-Cyanoindole-3-carboxyaldehyde
5-Cyanoindole-3-carboxaldehyde
1H-Indole-5-carbonitrile, 3-formyl-
3-Formylindole-5-carbonitrile
MFCD01719101
INDOLE-5-CARBONITRILE, 3-FORMYL-
3-Formyl-5-cyano-1H-indole
5-Cyano-1H-indole-3-carboxaldehyde
5-Cyano-3-formyl indole
BRN 0389069
5-22-06-00313 (Beilstein Handbook Reference)
SCHEMBL2535253
SCHEMBL30665978
DTXSID00169661
NVBCFOQYDFKXJJ-UHFFFAOYSA-N
ALBB-035494
BBL029455
SBB088401
STK649226
AKOS005259085
CS-W019424
DS-0053
FC52341
SB15258
NCGC00337484-01
SY056966
3-Formyl-1H-indole-5-carbonitrile, 97%
DB-001524
EN300-107720
AB01328762-02
Z1255373027