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Edelfosine

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Identification
Molecular formula
C39H75NO6P
CAS number
77286-26-9
IUPAC name
(3-hexadecoxy-2-icosa-5,8,11,14-tetraenoyloxy-propyl) 2-(trimethylammonio)ethyl phosphate
State
State

At room temperature, Edelfosine is generally in a liquid state or a viscous semi-solid, depending on the purity and specific supplier formulation. It can sometimes also be supplied as a solid coating on research slides.

Melting point (Celsius)
254.15
Melting point (Kelvin)
527.30
Boiling point (Celsius)
473.10
Boiling point (Kelvin)
746.25
General information
Molecular weight
605.96g/mol
Molar mass
605.9620g/mol
Density
1.0480g/cm3
Appearence

Edelfosine is typically a viscous, colorless to pale yellow liquid. It is often supplied in solution or as a coating agent in various biomedical research applications.

Comment on solubility

Solubility of (3-hexadecoxy-2-icosa-5,8,11,14-tetraenoyloxy-propyl) 2-(trimethylammonio)ethyl phosphate

The solubility of the compound with the formula C39H75NO6P presents some interesting characteristics due to its unique structure. This compound is amphiphilic, comprising both hydrophilic and hydrophobic portions, which significantly influences its solubility in different solvents.

Factors Affecting Solubility

Several factors contribute to the solubility of this complex molecule:

  • Hydrophobic Alkyl Chains: The presence of long hydrocarbon chains, such as the hexadecoxy and icosadienoic portions, enhances the molecule's solubility in non-polar solvents, such as hydrocarbons or organic solvents.
  • Hydrophilic Phosphate Group: The trimethylammonium and phosphate functional groups increase solubility in polar solvents, particularly water, as they can interact favorably through ion-dipole and hydrogen bonding.
  • Temperature: Like most compounds, solubility may vary with temperature; typically, increased temperatures enhance solubility for solid compounds.

General Solubility Characteristics

In general, one can expect:

  • This compound to exhibit moderate solubility in polar solvents due to its ionic nature from the trimethylammonioethyl phosphate.
  • It may have limited solubility in pure water because of the substantial hydrophobic character imparted by the long hydrocarbon chains.
  • Solubility in biological environments could be enhanced due to membrane interactions, particularly regarding its use in biological studies.

In conclusion, the solubility of C39H75NO6P is a complex interplay between its amphiphilic nature and the surrounding solvent environment, making it a fascinating compound for both practical applications and academic study.

Interesting facts

Interesting Facts about (3-hexadecoxy-2-icosa-5,8,11,14-tetraenoyloxy-propyl) 2-(trimethylammonio)ethyl phosphate

This complex compound is an intriguing example of how organic chemistry can create specialized molecules with a variety of applications. Here are some fascinating aspects of this compound:

  • Phospholipid-like Properties: The presence of a phosphate group suggests that this compound may exhibit phospholipid characteristics. Such molecules play a crucial role in the formation of cellular membranes, allowing for the study of membrane dynamics and function.
  • Biological Relevance: Given its amphiphilic nature, it may interact with biological systems, making it of interest in drug delivery and other biotechnological applications. Surfactant properties can enhance the solubility and bioavailability of hydrophobic drugs.
  • Structural Diversity: The long aliphatic chains in its structure (such as hexadecyloxy and icosa-tetraenoyloxy groups) contribute to its unique physical and chemical properties, which can be tuned for specific applications in materials science.
  • Potential for Stabilization: This compound could serve as a stabilizer or emulsifier in various formulations, including cosmetics and pharmaceuticals. Its ability to form micelles and liposomes is of great interest in formulation chemistry.
  • Research Tool: As a synthetic molecule, it may be utilized in various experimental settings to explore interactions between lipid bilayers and proteins, contributing to our understanding of molecular biology.

In summary, the complexity of (3-hexadecoxy-2-icosa-5,8,11,14-tetraenoyloxy-propyl) 2-(trimethylammonio)ethyl phosphate showcases the versatility and ingenuity required in modern chemistry. As researchers continue to explore such compounds, we gain deeper insights into the molecular foundations of life and the development of innovative technologies.

Synonyms
LDA28811
C16-20:4 PC
PD050170