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Identification
Molecular formula
C19H28O2
CAS number
58-22-0
IUPAC name
3-hydroxy-13-methyl-12,14,15,16-tetrahydro-11H-cyclopenta[a]phenanthren-17-one
State
State

Solid at room temperature.

Melting point (Celsius)
155.00
Melting point (Kelvin)
428.15
Boiling point (Celsius)
413.00
Boiling point (Kelvin)
686.15
General information
Molecular weight
288.42g/mol
Molar mass
288.4240g/mol
Density
1.1450g/cm3
Appearence

White to yellowish crystalline powder.

Comment on solubility

Solubility of 3-hydroxy-13-methyl-12,14,15,16-tetrahydro-11H-cyclopenta[a]phenanthren-17-one

The solubility of 3-hydroxy-13-methyl-12,14,15,16-tetrahydro-11H-cyclopenta[a]phenanthren-17-one can be attributed to its unique structural features, which influence its interaction with solvents. Generally, the solubility of organic compounds can be understood through the principle of "like dissolves like". Here are some key points to consider:

  • Polarity: The presence of the hydroxyl group (-OH) in the molecule suggests that it may exhibit some polar characteristics, potentially allowing it to dissolve in polar solvents, such as water or methanol.
  • Hydrophobic portions: With a significant hydrocarbon framework, the hydrophobic portions of this compound may limit solubility in polar solvents while promoting solubility in non-polar solvents like hexane or chloroform.
  • Temperature dependency: As with many organic substances, the solubility might increase with temperature, which promotes higher kinetic energy and solute-solvent interactions.
  • Hydrogen bonding: The ability of the hydroxyl group to form hydrogen bonds can enhance solubility in certain solvents, particularly alcohols.

In summary, while this compound may have varying solubility depending on the solvent, it is likely to be more soluble in non-polar solvents due to its large and complex hydrocarbon structure, while still retaining some ability to dissolve in polar environments because of its hydroxyl functional group. Understanding these solubility characteristics is essential for applications in formulations and chemical processes.

Interesting facts

Interesting Facts About 3-Hydroxy-13-methyl-12,14,15,16-tetrahydro-11H-cyclopenta[a]phenanthren-17-one

This intriguing compound is a member of the cyclopenta[a]phenanthrene family. As a chemical scientist, you will find its structure and characteristics quite fascinating! Here are some notable points:

  • Structural Complexity: The compound's intricate structure features multiple fused rings, which is a hallmark of many biologically active compounds. This complexity can lead to unique chemical behavior and potential interactions with biological systems.
  • Hydroxyl Group Influence: The presence of the hydroxyl group at position 3 plays a crucial role in its reactivity and polarity, often contributing to its solubility and biological activity.
  • Potential Applications: Similar compounds have been studied for their potential use in medicinal chemistry, particularly in the development of pharmaceuticals targeting various diseases.
  • Biological Significance: Compounds like these are often found in plant sources and may exhibit anti-inflammatory or anti-cancer properties, opening avenues for research in herbal medicine and drug development.
  • Synthetic Challenges: Chemists may find the synthetic route to this compound challenging, illustrating the complexities involved in constructing multi-ring structures with precision.

As you delve deeper into the world of organic compounds, the study of 3-hydroxy-13-methyl-12,14,15,16-tetrahydro-11H-cyclopenta[a]phenanthren-17-one offers an excellent opportunity to explore the intersection of chemistry and biology, emphasizing the power of molecular design in the pursuit of new therapeutic agents.

Synonyms
Isoequilenin
3-hydroxy-13-methyl-12,14,15,16-tetrahydro-11H-cyclopenta[a]phenanthren-17-one
SCHEMBL1649212
DTXSID40859438
NSC9901
PDRGHUMCVRDZLQ-UHFFFAOYSA-N
WLN: L E5 B666 FVTT&&J E1 OQ
NS00002296
Estra-1,5,7,9-pentaen-17-one, 3-hydroxy-
3-Hydroxyestra-1,5(10),6,8-pentaen-17-one
Estra-1,5(10),6,8-pentaen-17-one, 3-hydroxy-
3-HYDROXY-13-METHYL-HEXAHYDRO-CYCLOPENTA(A)PHENANTHREN-17-ONE
7-Hydroxy-11a-methyl-2,3,3a,10,11,11a-hexahydro-1H-cyclopenta[a]phenanthren-1-one
902274-40-2