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Estradiol cyclopentylpropionate

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Identification
Molecular formula
C26H38O3
CAS number
313-06-4
IUPAC name
(3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl) 3-cyclopentylpropanoate
State
State

At room temperature, estradiol cyclopentylpropionate exists as a solid in the form of a white crystalline powder. It remains stable when stored in cool, dry conditions away from light and air.

Melting point (Celsius)
142.00
Melting point (Kelvin)
415.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
414.61g/mol
Molar mass
414.6140g/mol
Density
1.2000g/cm3
Appearence

The compound appears as a white or off-white crystalline powder. It is odorless and stable under recommended storage conditions. Its hydrophobic nature means it does not dissolve well in water, but it is soluble in organic solvents like ethanol and chloroform.

Comment on solubility

Solubility of (3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl) 3-cyclopentylpropanoate

The compound with the formula C26H38O3 presents interesting solubility characteristics that are important to consider in various chemical and biological contexts. Here are some key points regarding its solubility:

  • Polarity: Given its structure, the presence of hydroxyl (–OH) groups suggests that the compound has moderate polarity, which can influence its solubility in polar solvents like water.
  • Hydrocarbon Backbone: The long hydrocarbon chain may lead to significant hydrophobic characteristics, which can decrease solubility in polar environments while enhancing solubility in non-polar organic solvents.
  • Solvent Compatibility: Based on its molecular structure, it is likely soluble in organic solvents such as:
    • Ethyl acetate
    • Toluene
    • Dichloromethane

As a general rule, the solubility of organic compounds varies widely depending on temperature, pH, and solvent environment. In summary, one might say that while the presence of polar functional groups may allow for some solubility in polar solvents, the predominant hydrocarbon components can lead to enhanced solubility in more non-polar conditions.

Interesting facts

Interesting Facts about (3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl) 3-cyclopentylpropanoate

This compound represents a fascinating class of organic molecules known for their structural complexity and potential biological activities. Here are some engaging insights:

  • Structural Diversity: The intricate structure of this compound, featuring multiple fused ring systems and hydroxy substituents, showcases the beauty of organic chemistry. The cyclopentyl group adds a unique twist to its molecular architecture.
  • Biological Relevance: Compounds like this one are often explored in medicinal chemistry for their potential use as therapeutic agents. The presence of a hydroxyl group can enhance interactions with biological targets, potentially leading to increased efficacy in drug design.
  • Natural Occurrence: Compounds featuring similar frameworks are frequently found in nature, particularly among steroids and terpenes, hinting at their evolutionary significance.
  • Synthesis Challenges: The synthesis of such a complex molecule poses interesting challenges. Chemists often employ multi-step reactions and advanced techniques, such as stereoselective synthesis, to construct these intricate arrangements.
  • Potential Applications: Beyond medicine, compounds with decahydrocyclopenta frameworks have applications in materials science and could inspire the development of new polymers or nanomaterials due to their unique physical properties.
  • Research Opportunities: As the study of this compound and its analogs continues, scientists remain on the lookout for novel biological activities, leading to potential breakthroughs in various fields including pharmacology and biochemistry.

In conclusion, (3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl) 3-cyclopentylpropanoate is not just a chemical entity; it's a window into the vast and intricate world of organic chemistry, offering both challenges and opportunities for scientists and researchers alike.

Synonyms
3-Hydroxyestra-1,3,5(10)-trien-17-yl 3-cyclopentylpropanoate
Estra-1,3,5(10)-triene-3,17-diol (17.beta.)-, 17-cyclopentanepropanoate
beta -Estradiol 17-cypionate
SCHEMBL20130822
DTXSID30859326
AKOS025401445
AC-1672
,17beta-Hydroxy-1,3,5(10)-estratriene 17-cyclopentylpropionate
(17b)-estra-1,3,5(10)-triene-3,17-diol 17-cyclopentane propanoate