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Estradiol propionate

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Identification
Molecular formula
C21H28O3
CAS number
313-06-4
IUPAC name
(3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl) propanoate
State
State

Estradiol propionate is typically solid at room temperature and is often found in crystalline form.

Melting point (Celsius)
146.00
Melting point (Kelvin)
419.15
Boiling point (Celsius)
566.40
Boiling point (Kelvin)
839.55
General information
Molecular weight
384.52g/mol
Molar mass
384.5230g/mol
Density
1.1600g/cm3
Appearence

Estradiol propionate appears as a white or off-white crystalline powder. It tends to have no or a very faint odor.

Comment on solubility

Solubility of (3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl) propanoate: C21H28O3

The solubility of (3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl) propanoate can be characterized as follows:

  • Non-polar Character: This compound has a significant hydrophobic character due to its large carbon skeleton, which suggests limited solubility in polar solvents such as water.
  • Moderate Solubility: It may exhibit moderate solubility in organic solvents like chloroform or ethanol, which can stabilize its molecular structure.
  • Influencing Factors: Factors such as temperature, presence of co-solvents, and pH can play a crucial role in its solubility behavior.

In conclusion, while the solubility of this compound in water is likely to be low, it might easily dissolve in organic solvents due to its non-polar characteristics. Understanding the solubility profile is crucial for further applications and formulations in various chemical contexts.

Interesting facts

Interesting Facts about (3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl) propanoate

This fascinating compound is part of a class of organic molecules known as steroids, which play critical roles in biological functions. Here are some engaging insights about this particular compound:

  • Natural Origins: Many compounds similar in structure can be derived from natural sources, particularly plants and certain fungi, showcasing nature's ability to synthesize complex organic molecules.
  • Biological Significance: The presence of hydroxyl groups in such compounds often enhances their reactivity and interaction with biological systems, making them vital in studies of hormone function and regulation.
  • Structure-Activity Relationship: The intricate arrangement of bonds in this molecule serves as an excellent example of how tiny structural changes can lead to vastly different biological activities and properties.
  • Synthesis: The synthesis of such complex organic compounds demands a high degree of synthetic skill and creativity, often requiring multiple steps and various reagents, reflecting the complex nature of organic chemistry.
  • Pharmacological Applications: Similar steroids are often explored for their therapeutic potential, particularly in the fields of endocrinology and oncology, as they can mimic or influence hormonal pathways.

This compound exemplifies the intricate world of organic chemistry, highlighting not only its structural complexity but also the profound implications its functional groups have in biological systems. As stated by chemistry enthusiasts, "The beauty of chemistry lies in its ability to explain the world around us in terms of structures and interactions."
Understanding this compound opens doors to further research and exploration in medicinal chemistry and beyond.

Synonyms
estradiol propionate
beta-Estradiol 17-propionate
NCGC00183033-01
DivK1c_000514
Estra-1,3,5(10)-triene-3,17-diol (17.beta.)-, 17-propanoate
.beta.-Estradiol 17-propionate
CHEMBL5487961
HMS501J16
KBio1_000514
DTXSID00859838
NINDS_000514
PQCRZWCSVWBYSC-UHFFFAOYSA-N
IDI1_000514
3-hydroxyestra-1,3,5(10)-trien-17-yl propanoate
beta-Estradiol 17-propionate, VETRANAL(TM), analytical standard