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3-Hydroxy-2-methylpropanenitrile

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Identification
Molecular formula
C4H7NO
CAS number
630-93-3
IUPAC name
3-hydroxy-2-methyl-propanenitrile
State
State

At room temperature, 3-hydroxy-2-methylpropanenitrile is in a liquid state. It is often handled in a standard laboratory or industrial settings under ambient conditions.

Melting point (Celsius)
-37.00
Melting point (Kelvin)
236.15
Boiling point (Celsius)
193.00
Boiling point (Kelvin)
466.15
General information
Molecular weight
85.10g/mol
Molar mass
85.1000g/mol
Density
0.9270g/cm3
Appearence

3-Hydroxy-2-methylpropanenitrile is typically a colorless liquid. It may have a faint odor. The appearance can vary slightly depending on the purity and specific conditions in which it is handled or synthesized, but it is generally clear if pure.

Comment on solubility

Solubility of 3-hydroxy-2-methyl-propanenitrile

3-hydroxy-2-methyl-propanenitrile (C4H7N) exhibits an interesting solubility profile that can be influenced by various factors. Here are some key points to consider:

  • Polarity: The presence of the hydroxyl group (-OH) contributes to the polarity of the molecule, which generally enhances solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to engage in hydrogen bonding allows 3-hydroxy-2-methyl-propanenitrile to dissolve in alcohols and other hydrogen-bonding solvents more readily.
  • Solvent Effects: In non-polar solvents, solubility is expected to be lower due to the molecule's polar nature, aligning with the principle of "like dissolves like."
  • Temperature: Increased temperature can sometimes improve solubility, making it easier for the compound to dissolve in various solvents.

As a summary, 3-hydroxy-2-methyl-propanenitrile is likely to be soluble in polar solvents due to its functional groups, while showing limited solubility in non-polar media. Understanding these solubility characteristics is crucial for the compound's applications in both research and industrial contexts.

Interesting facts

Interesting Facts about 3-Hydroxy-2-methyl-propanenitrile

3-Hydroxy-2-methyl-propanenitrile is a compound of notable interest in the fields of organic chemistry and biochemistry. Here are some fascinating points worth exploring:

  • Functional Groups: This compound features both a hydroxyl group (-OH) and a nitrile group (-C≡N), which play crucial roles in its chemical reactivity and properties.
  • Synthetic Utility: 3-Hydroxy-2-methyl-propanenitrile can serve as an important intermediate in the synthesis of various pharmaceuticals and agrochemicals, thus highlighting its significance in synthetic organic chemistry.
  • Biological Relevance: It is of interest due to its potential biological activities. Compounds with similar structures have been studied for their antitumor and antimicrobial properties.
  • Versatile Reactivity: The presence of both the nitrile and hydroxyl functional groups allows for a range of chemical transformations, including nucleophilic additions and condensation reactions, broadening its applicability in diverse chemical syntheses.
  • Structure-Activity Relationship (SAR): The variations in the structure of 3-hydroxy-2-methyl-propanenitrile can lead to different biological activities, making it a subject of research in medicinal chemistry as scientists seek to optimize the efficacy of related compounds.

In conclusion, 3-hydroxy-2-methyl-propanenitrile stands out not only for its unique chemical structure but also for its potential contributions to both industrial chemistry and pharmacology. As we delve deeper into its properties and applications, the compound may yield surprising discoveries that could benefit various fields.

Synonyms
3-hydroxy-2-methylpropanenitrile
3-Hydroxy-2-methylpropiononitrile
PROPYLENE CYANOHYDRIN
Propanenitrile, 3-hydroxy-2-methyl-
beta-hydroxyisobutyronitrile
DTXSID50948549
EINECS 219-902-2
2-METHYLHYDRACRYLONITRILE
DTXCID501376780
HYDRACRYLONITRILE, 2-METHYL-
219-902-2
2567-01-3
COZQDNPLORIALF-UHFFFAOYSA-N
AKOS009387606
CS-0222830
NS00045548
EN300-112802
Z406338220