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Quinoline Yellow

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Identification
Molecular formula
C16H11NO3
CAS number
8004-92-0
IUPAC name
3-hydroxy-2-phenyl-quinoline-4-carboxylic acid
State
State

At room temperature, Quinoline Yellow is in a solid state. It is typically found as a fine powder and retains its structure under standard laboratory conditions.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.00
Boiling point (Celsius)
528.00
Boiling point (Kelvin)
801.15
General information
Molecular weight
259.27g/mol
Molar mass
259.2670g/mol
Density
1.4000g/cm3
Appearence

Quinoline Yellow typically appears as a yellow or yellow-green crystalline powder. The intensity of its color can vary, providing vivid hues when dissolved in different solvents, especially in alkaline conditions.

Comment on solubility

Solubility of 3-hydroxy-2-phenyl-quinoline-4-carboxylic acid

The solubility of 3-hydroxy-2-phenyl-quinoline-4-carboxylic acid can be an intriguing topic due to its unique structure, which influences how it interacts with different solvents. In general, the solubility of this compound can be summarized as follows:

  • Polar solvents: The presence of a carboxylic acid group typically enhances solubility in polar solvents such as water. However, due to the hydrophobic phenyl group, it may have limited solubility.
  • Non-polar solvents: The phenyl ring contributes to increased solubility in non-polar organic solvents like benzene or toluene, making it more hydrophobic overall.
  • Solvent pH: The ionization of the carboxylic acid at higher pH levels can increase solubility in aqueous solutions, allowing for better interactions with water.

It is essential to consider that solubility can significantly depend on temperature and the specific conditions under which the compound is dissolved. As a result, when discussing solubility, one should also note:

  • Temperature Effects: Elevated temperatures may enhance solubility, allowing for greater dissolution of the compound.
  • Concentration Dependence: The solubility limit is a crucial factor, as oversaturation may lead to precipitation.

Therefore, the solubility behavior of this quinoline derivative can be quite complex, allowing for a rich area of study in both laboratory settings and potential applications.

Interesting facts

Interesting Facts about 3-Hydroxy-2-phenyl-quinoline-4-carboxylic Acid

3-Hydroxy-2-phenyl-quinoline-4-carboxylic acid is a fascinating compound that blends the intricate frameworks of quinoline and carboxylic acids. Here are some remarkable aspects of this compound:

  • Biological Significance: This compound has gained attention due to its potential biological activities, including antimicrobial and antioxidant properties. These activities make it an interesting subject of study in pharmaceutical chemistry.
  • Structural Features: The presence of both the hydroxy and carboxylic acid functional groups contributes to its acidity and reactivity, opening avenues for various chemical transformations and derivatizations.
  • Applications in Dyes: The quinoline framework is often utilized in dye synthesis, showcasing the versatility of 3-hydroxy-2-phenyl-quinoline-4-carboxylic acid in creating vibrant colorants used in textiles and other materials.
  • Synthetic Pathways: The synthesis of this compound involves several steps, typically starting from simpler quinoline derivatives. This complexity provides a rich field for chemists interested in organic synthesis and reaction mechanisms.
  • Research Insights: Studies have shown that analogs of this compound can lead to more effective pharmacological agents, emphasizing the importance of structure-activity relationships in drug design.

In summary, 3-hydroxy-2-phenyl-quinoline-4-carboxylic acid is not merely a chemical entity; it represents a confluence of biological activity, synthetic chemistry, and industrial application. As research continues, its significance in therapeutic development and material science will likely expand.

Synonyms
Oxycinchophen
485-89-2
oxicinchophen
Fenidrone
Chinoxone
Oxinofen
Hydroxycinchophene
Magnofenyl
Magnophenyl
Reumartril
Sintofene
3-Hydroxycinchophen
Oxicinchophenum
Oxicincofeno
Oxycinchophene
3-Hydroxy-2-phenylcinchoninic acid
Oxycinchopen
Oxycinchophenum
Oxycinchophen [INN:BAN]
3-Hydroxy-2-phenyl-4-quinolinecarboxylic acid
Oxicincofeno [INN-Spanish]
Oxycinchophene [INN-French]
Oxycinchophenum [INN-Latin]
HYDROXYCINCOPHENE
3-Hydroxy-2-phenyl-chinchoninsaeure
EINECS 207-624-4
NSC 41784
NSC-41784
BRN 0224526
UK6392GD5W
Oxycinchophen (INN)
DTXSID0057750
CINCHONINIC ACID, 3-HYDROXY-2-PHENYL-
4-Quinolinecarboxylic acid, 3-hydroxy-2-phenyl-
OXYCINCHOPHEN [MI]
OXYCINCHOPHEN [INN]
OXYCINCHOPHEN [WHO-DD]
DTXCID7031539
4-22-00-02383 (Beilstein Handbook Reference)
Oxicincofeno (INN-Spanish)
Oxycinchophene (INN-French)
Oxycinchophenum (INN-Latin)
4-Quinolinecarboxylic acid, 3-hydroxy-2-phenyl-(9CI)
207-624-4
3-hydroxy-2-phenylquinoline-4-carboxylic acid
CHEMBL219376
3-Hydroxy-2-phenyl-quinoline-4-carboxylic acid
WLN: T66 BNJ CR& DQ EVQ
UNII-UK6392GD5W
MFCD00023966
3-hydroxy-2-phenyl-4-quinoline carboxylic acid
Oprea1_702302
SCHEMBL1170683
CHEBI:135094
NSC41784
NSC49182
Tox21_113947
BDBM50201927
NSC-49182
AKOS015867059
DB13596
SB70121
NCGC00262955-01
AS-66799
CAS-485-89-2
DB-014287
HY-119453
CS-0068416
NS00022221
D07271
SR-01000944972
Q1227218
SR-01000944972-1