Skip to main content

Flunarizine

ADVERTISEMENT
Identification
Molecular formula
C26H26FN3O
CAS number
52468-60-7
IUPAC name
3-hydroxy-2,2-dimethyl-4-(3-oxocyclopenten-1-yl)oxy-chromane-6-carbonitrile
State
State
Flunarizine is typically in a solid crystalline state at room temperature.
Melting point (Celsius)
239.00
Melting point (Kelvin)
512.15
Boiling point (Celsius)
576.20
Boiling point (Kelvin)
849.35
General information
Molecular weight
404.50g/mol
Molar mass
404.4840g/mol
Density
1.3080g/cm3
Appearence

Flunarizine appears as a white to off-white crystalline powder. It is not very soluble in water, but is soluble in some organic solvents, such as ethanol or chloroform.

Comment on solubility

Solubility of 3-hydroxy-2,2-dimethyl-4-(3-oxocyclopenten-1-yl)oxy-chromane-6-carbonitrile

The solubility of the compound 3-hydroxy-2,2-dimethyl-4-(3-oxocyclopenten-1-yl)oxy-chromane-6-carbonitrile (C26H26FN3O) can be influenced by various factors. Understanding these factors is essential in predicting how this compound will behave in different solvents. Here are some key considerations:

  • Polarity: The presence of hydroxyl (-OH) and carbonitrile (-C≡N) functional groups indicates that this compound may exhibit some degree of polarity, potentially enhancing its solubility in polar solvents like water and methanol.
  • Apolar Parts: The substantial hydrocarbon character present in the structure (due to the numerous carbon atoms) suggests that the compound may have limited solubility in nonpolar solvents like hexane.
  • Hydrogen Bonding: The hydroxyl group may allow for hydrogen bonding with solvents, further influencing solubility favorably in protic solvents.
  • Temperature Effect: As with many organic compounds, the solubility may increase with temperature, leading to better dispersion in various solvents.

In summary, while the compound shows potential for solubility in polar solvents due to the hydroxyl group, its considerable organic structure may limit solubility in extreme nonpolar environments. Observing experimental data will provide the most reliable insight into its solubility properties.

Interesting facts

Interesting Facts about 3-hydroxy-2,2-dimethyl-4-(3-oxocyclopenten-1-yl)oxy-chromane-6-carbonitrile

3-hydroxy-2,2-dimethyl-4-(3-oxocyclopenten-1-yl)oxy-chromane-6-carbonitrile is a fascinating chemical compound with a rich chemical structure that holds intriguing potential in various fields. Here are some noteworthy aspects about this compound:

  • Bioactivity: This compound is of considerable interest in medicinal chemistry due to its promising bioactive properties. Compounds in this class can exhibit a range of biological activities, including antioxidant and anti-inflammatory effects.
  • Synthetic Route: The complexity of its molecular structure means that the synthesis of this compound requires sophisticated organic chemistry techniques, often involving multiple steps that demonstrate the capabilities of modern synthetic methods.
  • Potential Applications: The unique arrangement of functional groups in this molecule suggests potential applications in drug development, especially in areas related to cardiovascular health and neurodegenerative diseases.
  • Research Implications: Due to its various unique properties, this compound could serve as a valuable starting point for further research, encouraging studies into its mechanisms of action and potential therapeutics.
  • Structural Diversity: Featuring multiple chiral centers, this compound exemplifies the fascinating realm of stereochemistry that is crucial in understanding the interactions of molecules in biological systems.

In summary, 3-hydroxy-2,2-dimethyl-4-(3-oxocyclopenten-1-yl)oxy-chromane-6-carbonitrile not only showcases complexity in its structure but also opens avenues for exploration in pharmacology, organic synthesis, and medicinal applications. Its continued study could lead to significant advancements in various scientific disciplines.

Synonyms
PCO 400
SDZ-PCO-400
3-hydroxy-2,2-dimethyl-4-(3-oxocyclopenten-1-yl)oxy-3,4-dihydrochromene-6-carbonitrile
SCHEMBL9874277