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3-hydroxy-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one

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Identification
Molecular formula
C13H10N2O2
CAS number
6311-79-5
IUPAC name
3-hydroxy-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one
State
State

The compound is generally found as a solid at room temperature.

Melting point (Celsius)
239.50
Melting point (Kelvin)
512.70
Boiling point (Celsius)
490.50
Boiling point (Kelvin)
763.70
General information
Molecular weight
226.25g/mol
Molar mass
226.2510g/mol
Density
1.4123g/cm3
Appearence

3-Hydroxy-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one typically appears as a colorless to pale yellow crystalline solid. It is known for its distinct structural features, contributing to its appearance.

Comment on solubility

Solubility of 3-hydroxy-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one

The solubility of 3-hydroxy-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one can be influenced by several factors, and understanding these can provide insights into its potential applications. While specific solubility data may be limited, we can consider the following general aspects:

  • Polarity: The presence of the hydroxy group (-OH) contributes to the compound's polarity, suggesting it may have some degree of solubility in polar solvents like water or methanol.
  • Hydrogen bonding: The ability to form hydrogen bonds due to the hydroxy group can enhance solubility in polar organic solvents.
  • Solvent effects: The solubility may vary significantly with different solvents. For instance, it may be more soluble in dimethyl sulfoxide (DMSO) compared to less polar solvents.
  • Temperature: Temperature can also play a role; as temperature increases, solubility generally increases for many compounds due to enhanced molecular movement.

In summary, while direct solubility data for 3-hydroxy-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one may not be readily available, one can reasonably infer that its structural characteristics impart certain solubility traits in various solvent environments. Understanding these factors can aid researchers in predicting and enhancing its solubility behavior.

Interesting facts

Interesting Facts about 3-hydroxy-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one

This intriguing compound, with its distinct structure and functional groups, has captured the attention of researchers in various fields, particularly medicinal chemistry. Here are some fascinating insights:

  • Complex Structure: The compound features a fused pyrrole and quinazoline ring system, which contributes to its unique chemical properties and biological activity.
  • Biological Significance: Compounds resembling this structure have shown potential in pharmacology. Their activity often targets specific biological pathways, making them valuable in drug development.
  • Synthesis Challenges: The synthesis of this compound can present challenges due to the complexity of its rings. Researchers employ various strategies, including multi-step synthesis and innovative reaction conditions, to produce it efficiently.
  • Versatile Applications: Beyond its medicinal properties, compounds with similar frameworks may also find applications in materials science and organic electronics due to their electronic properties.
  • Future Research: Ongoing studies are exploring its role as a scaffold for new drug candidates, demonstrating that compounds like this one might hold the key to developing treatments for complex diseases.

In summary, the study of 3-hydroxy-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one opens a window into the exciting world of organic chemistry and drug discovery. As researchers continue to unveil its secrets, we may discover even more applications that can benefit society.

Synonyms
CHEMBL1864065
3-hydroxy-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one
(-)-Vasicinone;l-Vasicinone
l-Vazicinon
1H-Pyrrolo[2,1-b]quinazolin-9-one, 3-hydroxy-2,3-dihydro-
3-hydroxy-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one
Oprea1_477261
MLS001048974
MEGxp0_000490
SCHEMBL3892901
ACon1_000672
SDIVYZXRQHWCKF-UHFFFAOYSA-N
HMS1648K16
HMS2270I06
HMS3561H13
BDBM50594708
STL443724
AKOS004110717
AKOS021970056
SDCCGMLS-0065231.P001
NCGC00169472-01
NCGC00169472-02
SMR000386992
NS00018022
AH-214/20712002
BRD-A16720449-001-01-9
3-HYDROXY-1H,2H,3H,9H-PYRROLO[2,1-B]QUINAZOLIN-9-ONE