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3-Hydroxy-3-phenylindolin-2-one

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Identification
Molecular formula
C15H11NO2
CAS number
2553-64-0
IUPAC name
3-hydroxy-3-phenyl-indolin-2-one
State
State

At room temperature, 3-Hydroxy-3-phenyl-indolin-2-one is in a solid state. It is stable under typical conditions of handling and storage, making it suitable for a variety of applications in chemical synthesis and research.

Melting point (Celsius)
216.00
Melting point (Kelvin)
489.15
Boiling point (Celsius)
253.00
Boiling point (Kelvin)
526.15
General information
Molecular weight
237.26g/mol
Molar mass
237.2640g/mol
Density
1.3420g/cm3
Appearence

3-Hydroxy-3-phenyl-indolin-2-one typically appears as a yellow crystalline solid. It is often prepared as a pure, finely powdered material. The crystalline structure imparts a distinct gleam or shine to the compound under light reflection.

Comment on solubility

Solubility of 3-hydroxy-3-phenyl-indolin-2-one

The solubility of 3-hydroxy-3-phenyl-indolin-2-one can be quite intriguing due to its unique molecular structure. Generally speaking, the solubility of compounds like this one can depend on several factors:

  • Polarity: The presence of hydroxy groups typically increases the polarity of the molecule, enhancing solubility in polar solvents like water.
  • Hydrogen Bonding: The hydroxy group can engage in hydrogen bonding, which may facilitate solubility in polar environments.
  • Aromatic Interaction: The phenyl group could result in hydrophobic interactions, potentially lowering solubility in aqueous solutions.
  • Temperature: Solubility often increases with temperature, thus heating the solvent may assist in dissolving this compound.

In summary, while 3-hydroxy-3-phenyl-indolin-2-one has favorable characteristics for solubility in specific solvents, its overall behavior can vary significantly based on its environmental conditions. It is crucial to conduct empirical tests under varying conditions to determine the precise solubility of this compound.

Interesting facts

Interesting Facts about 3-Hydroxy-3-phenyl-indolin-2-one

3-hydroxy-3-phenyl-indolin-2-one is a fascinating compound that sits at the intersection of organic chemistry and medicinal research. Here are some compelling insights into this intriguing molecule:

  • Structural Complexity: This compound features an indole structure, a bicyclic heterocycle known for its role in many biological systems. Indoles are significant due to their presence in many natural products and pharmaceuticals.
  • Biological Significance: Compounds related to 3-hydroxy-3-phenyl-indolin-2-one have been studied for various biological activities. Research suggests potential applications in areas such as antioxidant and anticancer therapies, making it a subject of ongoing scientific interest.
  • Colorful Chemistry: Some derivatives of this compound exhibit interesting color properties due to their ability to form conjugated systems. This can lead to potential applications in dye chemistry or the development of visual indicators.
  • Synthesis Challenge: The synthesis of 3-hydroxy-3-phenyl-indolin-2-one involves multiple steps and requires careful handling of reagents. This complexity can serve as a valuable learning tool for students studying organic synthesis.
  • Pharmaceutical Research: Ongoing studies are investigating the activities of indolin-2-one derivatives as potential therapeutic agents. Such research often unveils new mechanisms of action that could lead to the development of novel drugs.

In summary, 3-hydroxy-3-phenyl-indolin-2-one not only exemplifies the beauty of organic chemistry through its intricate structure but also sparks curiosity through its potential applications in the pharmaceutical industry. As scientists continue to explore this compound, it underscores the blend of creativity and science that drives chemical discovery.

Synonyms
1848-24-4
3-Hydroxy-3-phenylindolin-2-one
3-hydroxy-3-phenyl-1H-indol-2-one
3-hydroxy-3-phenyl-1,3-dihydro-2H-indol-2-one
3-hydroxy-3-phenyl-indolin-2-one
3-Phenyldioxindole
3-Hydroxy-3-phenyl-2-oxindole
NSC 25395
3-HYDROXY-3-PHENYLOXINDOLE
NSC 55995
NSC 119463
BRN 0015389
2-INDOLINONE, 3-HYDROXY-3-PHENYL-
3-Phenyldioxindol
MFCD00047211
Maybridge1_006575
3-hydroxy-3-phenyl-2,3-dihydro-1H-indol-2-one
Oprea1_197466
CBDivE_014208
5-21-12-00572 (Beilstein Handbook Reference)
MLS000755639
SCHEMBL209276
CHEMBL1350030
HMS560C19
CYPJCGXWLXXEHL-UHFFFAOYSA-N
DTXSID801270787
HMS2618M14
NSC25395
NSC55995
NSC-25395
NSC-55995
NSC119463
3-Phenyl-3-hydroxy-3H-indol-2-one
AKOS015994135
CCG-247482
MS-0618
NSC-119463
SB65839
NCGC00246568-01
SMR000337308
DB-218082
3-Hydroxy-3-phenyl-1,3-dihydroindol-2-one
CS-0311940
3-Hydroxy-3-phenyl-1,3-dihydro-indol-2-one
Y13471
2H-Indol-2-one, 1,3-dihydro-3-hydroxy-3-phenyl-