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Kojic acid

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Identification
Molecular formula
C6H6O4
CAS number
501-30-4
IUPAC name
3-hydroxy-4-oxo-pyran-2,6-dicarboxylic acid
State
State

At room temperature, Kojic acid exists in a solid state. It is usually found as a crystalline powder that is easy to store and handle. Its stability and crystalline nature make it suitable for a variety of uses, particularly in the cosmetic industry.

Melting point (Celsius)
153.00
Melting point (Kelvin)
426.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
142.11g/mol
Molar mass
142.1120g/mol
Density
1.5800g/cm3
Appearence

Kojic acid is typically a white or slightly off-white crystalline powder. It may also appear as crystalline needles. The compound is known for its fine texture and is often found in a very pure form for various applications.

Comment on solubility

Solubility of 3-hydroxy-4-oxo-pyran-2,6-dicarboxylic acid

3-hydroxy-4-oxo-pyran-2,6-dicarboxylic acid, a complex organic compound, exhibits notable solubility characteristics that can be described in detail:

  • Polar Nature: Due to the presence of multiple carboxylic acid groups and hydroxyl groups, this compound is highly polar, which generally enhances its solubility in polar solvents.
  • Water Solubility: It is likely to have good solubility in water, attributed to hydrogen bonding and ionic interactions with water molecules.
  • Solvent Dependence: The solubility may vary significantly in different solvents. For example, it may show limited solubility in non-polar solvents like hexane.
  • pH Influence: The solubility can be affected by pH levels; in acidic conditions, the carboxylic groups may remain protonated, reducing solubility, while in basic conditions, greater dissociation may enhance solubility.

Overall, the solubility of 3-hydroxy-4-oxo-pyran-2,6-dicarboxylic acid is influenced by its functional groups, making it an interesting compound for studies involving solubility in various environments.

Interesting facts

Interesting Facts about 3-hydroxy-4-oxo-pyran-2,6-dicarboxylic acid

3-hydroxy-4-oxo-pyran-2,6-dicarboxylic acid, often referred to as a pyran derivative, is an intriguing compound with several significant properties and applications. Here are some fascinating insights:

  • Structural Characteristics: This compound features a unique pyran ring that contributes to its chemical behavior and reactivity. The positioning of the hydroxyl, ketone, and carboxylic acid functional groups plays a pivotal role in its interaction with other molecules.
  • Biological Relevance: Compounds like 3-hydroxy-4-oxo-pyran-2,6-dicarboxylic acid have been studied for their potential medicinal properties. Their structural motifs are often found in natural products and can be linked to biological activity, making them important in drug discovery.
  • Applications in Organic Synthesis: This compound can serve as an intermediate in organic synthesis, particularly in the development of more complex molecules. Its versatile functional groups allow chemists to manipulate and convert it into a variety of useful compounds.
  • Research Interest: The study of pyran derivatives, including 3-hydroxy-4-oxo-pyran-2,6-dicarboxylic acid, is a growing area in the field of chemistry. Researchers are investigating its potential applications in fields such as agriculture, where such compounds could act as agrochemicals.
  • Natural Occurrence: Some pyran derivatives are naturally occurring compounds found in plants and fungi. Their bioactive properties can contribute to their roles in ecological interactions, such as defense mechanisms against pests.

The exploration of 3-hydroxy-4-oxo-pyran-2,6-dicarboxylic acid exemplifies the importance of studying organic compounds not only for their immediate applications but also for the insight they provide into nature's chemistry. As stated by chemist Linus Pauling, "Scientists must use the tools of their trade to see the world in a new light," and compounds like this remind us of the endless possibilities within organic chemistry.

Synonyms
Meconic acid
497-59-6
Poppy acid
3-Hydroxy-4-oxopyran-2,6-dicarboxylic acid
oxychelidonic acid
Opium acid
3-Hydroxy-4-oxo-1,4-pyran-2,6-dicarboxylic acid
NSC 805
NSC-805
UNII-V502I79516
EINECS 207-848-2
MECONIC ACID [MI]
DTXSID2060096
V502I79516
3-hydroxy-4-pyrone-2,6-dicarboxylic acid
Meconate
DTXCID3040722
3-Hydroxy-4-oxopyran-2,6-dicarboxylate
zegrkmxcocrtcs-uhfffaoysa-n
3-HYDROXY-4-OXO-4H-PYRAN-2,6-DICARBOXYLIC ACID
CHEMBL109516
NSC805
Mekonsaure
Meconic acid (6CI); 3-Hydroxy-4-oxo-1,4-pyran-2,6-dicarboxylic acid; NSC 805; Poppy acid, 4H-Pyran-2,6-dicarboxylic acid, 3-hydroxy-4-oxo-; Meconic Acid
NoName_429
SCHEMBL546968
SCHEMBL600257
4H-Pyran-2,6-dicarboxylic acid, 3-hydroxy-4-oxo-
DTXSID20901328
CHEBI:166570
4H-Pyran-2, 3-hydroxy-4-oxo-
BDBM50147502
AKOS030554055
FM160058
DB-083476
NS00031960
3-hydroxy-4-oxo-pyran-2,6-dicarboxylic acid
C20209
AP-163/40806890
h-Pyran-2,6-dicarboxylic acid, 3-hydroxy-4-oxo-
Q421116