Skip to main content

Disperse Orange 3

ADVERTISEMENT
Identification
Molecular formula
C17H12N4O2
CAS number
730-40-5
IUPAC name
3-hydroxy-N-[4-[4-[(3-hydroxynaphthalene-2-carbonyl)amino]-3-methoxy-phenyl]-2-methoxy-phenyl]naphthalene-2-carboxamide
State
State

At room temperature, Disperse Orange 3 is typically in a solid state, owing to its relatively high melting point.

Melting point (Celsius)
208.00
Melting point (Kelvin)
481.00
Boiling point (Celsius)
401.85
Boiling point (Kelvin)
675.00
General information
Molecular weight
314.31g/mol
Molar mass
314.3100g/mol
Density
1.3430g/cm3
Appearence

Disperse Orange 3 is often presented as an orange powder. It can sometimes appear in different shades ranging from orange to reddish-brown depending on its specific polymorphic form and purity.

Comment on solubility

Solubility of 3-hydroxy-N-[4-[4-[(3-hydroxynaphthalene-2-carbonyl)amino]-3-methoxy-phenyl]-2-methoxy-phenyl]naphthalene-2-carboxamide

The solubility of 3-hydroxy-N-[4-[4-[(3-hydroxynaphthalene-2-carbonyl)amino]-3-methoxy-phenyl]-2-methoxy-phenyl]naphthalene-2-carboxamide can be quite complex due to its intricate molecular structure. Here are some key considerations regarding its solubility:

  • Polarity: The compound features several hydroxyl (−OH) and methoxy (−OCH3) groups, which can enhance solubility in polar solvents like water.
  • Hydrogen Bonding: The presence of functional groups capable of hydrogen bonding can significantly improve interactions with solvent molecules.
  • Structural Characteristics: The naphthalene rings contribute to hydrophobic character, which may limit solubility in highly polar solvents.
  • Solvent Selection: This compound may exhibit better solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO) rather than in water.

In summary, while the compound possesses various functional groups that suggest potential solubility in polar solvents, its overall solubility behavior is affected by the balance between hydrophobic and hydrophilic characteristics. Therefore, performing empirical solubility tests in various solvents is essential for determining its practical solubility.

Interesting facts

Exploring the Complexities of 3-Hydroxy-N-[4-[4-[(3-Hydroxynaphthalene-2-carbonyl)amino]-3-Methoxy-Phenyl]-2-Methoxy-Phenyl]Naphthalene-2-Carboxamide

This compound, with a notably intricate structure, embodies a fascinating intersection of organic chemistry and medicinal research. Here are some compelling points about this molecule:

  • Structural Complexity: The compound boasts a multi-ring system, integrating naphthalene units that contribute to its potential biological activity. Its structure enhances pharmacophore characteristics, making it a point of interest for drug design.
  • Biological Relevance: Compounds similar to this one have been studied for their potential as anti-cancer agents. The presence of the carboxamide and hydroxyl groups can influence interactions with biological targets, possibly impacting enzyme inhibition or receptor binding.
  • Substituent Effects: The complex arrangement of methoxy and hydroxyl groups modulates the electronic properties and solubility, which can affect the compound's biological activity and absorption characteristics.
  • Therapeutic Potential: Research into similar structures has shown promise in cancer therapies, suggesting that this compound might also exhibit cytotoxic properties against various cancer cell lines.
  • Research & Development: The synthesis and evaluation of compounds like this require advanced techniques in organic synthesis and characterization, making it a perfect subject for academic research and pharmaceutical applications.

In the world of medicinal chemistry, compounds like 3-hydroxy-N-[4-[4-[(3-hydroxynaphthalene-2-carbonyl)amino]-3-methoxy-phenyl]-2-methoxy-phenyl]naphthalene-2-carboxamide signify the intricate dance between structure, function, and therapeutic promise. As researchers delve deeper into such compounds, their potential to serve as innovative solutions in treating complex diseases like cancer becomes increasingly pronounced.

Synonyms
NAPHTHOL AS-BR
91-92-9
Azotol DA
Azoic Coupling Component 3
Naphtanilide BR
Sanatol BR
Amarthol AS-BR
Naphtol AS-BR
Hiltonaphthol AS-BR
Acco Naphthol AS-BR
Amanil Naphthol AS-BR
C.I. Azoic Coupling Component 3
Naphthol AS-BR C.I. 37575
C.I. 37575
2-Naphthalenecarboxamide, N,N'-(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[3-hydroxy-
2-Naphthalenecarboxamide, N,N'-(3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(3-hydroxy-
DTXSID0059033
4', 3,3''-dihydroxy-
2-Naphthalenecarboxamide,N'-(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[3-hydroxy-
EINECS 202-108-5
NSC 37224
n,n'-(3,3'-dimethoxybiphenyl-4,4'-diyl)bis(3-hydroxynaphthalene-2-carboxamide)
3-hydroxy-N-[4-[4-[(3-hydroxynaphthalene-2-carbonyl)amino]-3-methoxyphenyl]-2-methoxyphenyl]naphthalene-2-carboxamide
DTXCID4048725
SCHEMBL11094894
CCG-2510
EX-A7629
NSC37224
NSC50679
NSC-37224
NSC-50679
3,3'-Dihydroxy-N,N'-(3,3'-dimethoxybiphenyl-4,4'-diyl)di-2-naphthamide
AKOS001482915
DA-65931
MS-30460
HY-121932
CS-0083691
NS00021385
G12196
4',4'''-Bi-2-naphth-o-anisidide, 3,3''-dihydroxy-
N,N'-(3,3'-Dimethoxy-4,4'-biphenyldiyl)bis(3-hydroxy-2-naphthamide)
3-HYDROXY-N-[4'-(3-HYDROXYNAPHTHALENE-2-AMIDO)-3,3'-DIMETHOXY-[1,1'-BIPHENYL]-4-YL]NAPHTHALENE-2-CARBOXAMIDE