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mitomycin C

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Identification
Molecular formula
C15H18N4O5
CAS number
50-07-7
IUPAC name
3-(hydroxymethyl)-1-methyl-5-(2-methylaziridin-1-yl)-2-phenyl-indole-4,7-dione
State
State

Mitomycin C is typically found in a solid state at room temperature, appearing as powder.

Melting point (Celsius)
360.00
Melting point (Kelvin)
633.15
Boiling point (Celsius)
80.00
Boiling point (Kelvin)
353.15
General information
Molecular weight
334.33g/mol
Molar mass
334.3270g/mol
Density
1.3000g/cm3
Appearence

Mitomycin C is a blue-violet crystalline powder. It is typically quite vivid in color, indicating its presence when isolated.

Comment on solubility

Solubility of 3-(hydroxymethyl)-1-methyl-5-(2-methylaziridin-1-yl)-2-phenyl-indole-4,7-dione

The solubility of 3-(hydroxymethyl)-1-methyl-5-(2-methylaziridin-1-yl)-2-phenyl-indole-4,7-dione (C15H18N4O5) can be characterized based on several factors. Given its complex structure, which includes both hydrophobic and hydrophilic functional groups, the solubility behavior is quite intriguing.

Factors Influencing Solubility:

  • Molecular Structure: The presence of indole and aziridine components contributes to its unique solubility profile.
  • Hydroxymethyl Group: This group enhances the potential for hydrogen bonding with solvents, thereby increasing solubility in polar solvents.
  • Hydrophilicity vs. Hydrophobicity: The balance between hydrophilic (water-attracting) and hydrophobic (water-repelling) parts dictates the compound's solubility in various media.

In general, compounds with similar structures may demonstrate varied solubility due to differences in intermolecular forces. For instance:

  1. Highly polar solvents, such as water or methanol, might dissolve the compound effectively due to hydrogen bonding.
  2. Less polar solvents, such as chloroform or ether, may provide lower solubility levels.

As with many organic compounds, determining the exact solubility can be critically dependent upon temperature and pH, making experimental measurements essential for precise applications. Therefore, it is crucial to consider the solvation dynamics when evaluating the interactions of this compound in various environments.

Interesting facts

Interesting Facts about 3-(hydroxymethyl)-1-methyl-5-(2-methylaziridin-1-yl)-2-phenyl-indole-4,7-dione

The compound 3-(hydroxymethyl)-1-methyl-5-(2-methylaziridin-1-yl)-2-phenyl-indole-4,7-dione is a fascinating molecule that combines multiple functional groups and structural elements, making it of significant interest in the field of organic chemistry. Here are some intriguing points about this compound:

  • Structural Diversity: This compound features a complex architecture that includes an indole ring structure, which is crucial in many biological systems, especially in pharmaceuticals.
  • Biological Relevance: Indole derivatives, such as this one, are known for their diverse biological activities, including antitumor and antimicrobial properties. This makes them valuable in medicinal chemistry.
  • Aziridine Integration: The presence of a 2-methylaziridine unit introduces a three-membered ring that is highly strained. Such rings are often exploited in synthetic chemistry for the introduction of functional groups through ring-opening reactions.
  • Hydroxymethyl Functionality: The hydroxymethyl group is notable for its ability to participate in various chemical reactions, potentially modifying the compound's reactivity and interaction with biological targets.
  • Synthetic Pathways: The synthesis of this compound may involve several steps, utilizing methods such as cyclization and functional group transformations, showcasing the synthetic complexity often required for indole derivatives.

As a scientist or student, understanding the nuanced interactions and applications of such compounds can elucidate pathways for the development of new therapeutics. The structure-activity relationship (SAR) associated with these types of molecules can guide researchers in designing more effective and selective drugs.

In summary, the study of 3-(hydroxymethyl)-1-methyl-5-(2-methylaziridin-1-yl)-2-phenyl-indole-4,7-dione not only enhances our understanding of complex organic compounds but also serves as a promising avenue for future research in drug development.

Synonyms
CHEMBL133323
SCHEMBL23752276
PD037908
3-hydroxymethyl-5-(2-methylaziridin-1-yl)-1-methyl-2-phenylindole-4,7-dione