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(3-hydroxyphenyl)urea

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Identification
Molecular formula
C7H8N2O2
CAS number
645-16-1
IUPAC name
(3-hydroxyphenyl)urea
State
State

At room temperature, (3-hydroxyphenyl)urea is in a solid state.

Melting point (Celsius)
213.00
Melting point (Kelvin)
486.15
Boiling point (Celsius)
313.60
Boiling point (Kelvin)
586.75
General information
Molecular weight
152.15g/mol
Molar mass
152.1530g/mol
Density
1.4776g/cm3
Appearence

(3-Hydroxyphenyl)urea typically appears as a solid crystalline powder. The color of the powder can range from pale to off-white, depending on purity and conditions of storage or synthesis.

Comment on solubility

Solubility of (3-hydroxyphenyl)urea

(3-hydroxyphenyl)urea, whose chemical formula can be represented as C7H8N2O, displays interesting solubility characteristics that align with its functional groups. This compound's solubility can be influenced by several factors, including temperature, pH, and the presence of solvent.


Key Points Regarding Solubility:

  • Polar Nature: Due to the hydroxyl group (-OH), (3-hydroxyphenyl)urea is relatively polar, which enhances its solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds through the hydroxyl group contributes significantly to its interaction with water molecules, aiding its dissolution.
  • Lower Solubility in Non-Polar Solvents: Conversely, (3-hydroxyphenyl)urea is expected to have low solubility in non-polar solvents due to a lack of significant intermolecular interactions.

In general, we can conclude that (3-hydroxyphenyl)urea is more soluble in polar solvents and less so in non-polar environments. This characteristic can play a pivotal role in its applications and utilization in various chemical processes.

Interesting facts

Interesting Facts about (3-Hydroxyphenyl)urea

(3-Hydroxyphenyl)urea is a fascinating compound that sits at the intersection of organic chemistry and pharmaceuticals. Here are some engaging points about this unique substance:

  • Chemical Structure: The compound features a urea moiety bonded to a phenolic group, specifically at the meta position. This unique configuration contributes to its versatile chemical properties.
  • Biological Relevance: (3-Hydroxyphenyl)urea has garnered attention in medicinal chemistry due to its potential applications in drug development, particularly in targeting certain diseases and conditions.
  • Research Potential: Studies have indicated that similar compounds may exhibit antitumor activity, making (3-hydroxyphenyl)urea a subject of interest in cancer research.
  • Mechanism of Action: Investigations into the mechanism of (3-hydroxyphenyl)urea reveal its potential ability to interact with specific biological pathways, providing insights into new therapeutic strategies.
  • Applications: Beyond its biological significance, this compound is used as a research tool, helping scientists understand various biochemical processes and cellular mechanisms.
  • Future Prospects: As research continues, (3-hydroxyphenyl)urea may pave the way for new discoveries in pharmacology and beyond, highlighting the importance of small organic molecules in modern science.

In summary, (3-hydroxyphenyl)urea is not just an ordinary compound; it encapsulates the essence of how simple molecular changes can lead to significant biological implications. With ongoing research, it holds promise for exciting developments in the medical field and a deeper understanding of complex biological systems.

Synonyms
701-82-6
1-(3-Hydroxyphenyl)urea
m-Hydroxyphenylurea
(3-Hydroxyphenyl)urea
3-Ureidophenol
N-(3-Hydroxyphenyl)urea
Urea, (3-hydroxyphenyl)-
Urea, (m-hydroxyphenyl)-
Urea, N-(3-hydroxyphenyl)-
QE8R3LQ24N
NSC 60733
EINECS 211-860-3
NSC 14672
NSC-14672
NSC-60733
AI3-61347
DTXSID1061027
DTXCID7046621
Urea, (m-hydroxyphenyl)-(8CI)
211-860-3
3-HYDROXYPHENYLUREA
N-Carbamyl-m-aminophenol
Urea,N-(3-hydroxyphenyl)-
3-ureido phenol
MFCD00007945
N-Carbamoyl-3-aminophenol
UNII-QE8R3LQ24N
N-(3-Hydroxyphenyl)urea #
SCHEMBL3185695
CHEBI:229247
ALBB-035798
NSC14672
NSC60733
BBL007869
STK802343
AKOS005622607
VS-01743
DB-055386
CS-0207240
H0438
NS00037013
D90870
EN300-1232807
Z335810106
InChI=1/C7H8N2O2/c8-7(11)9-5-2-1-3-6(10)4-5/h1-4,10H,(H3,8,9,11