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3-hydroxypyridine-2-carboxylic acid

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Identification
Molecular formula
C6H5NO3
CAS number
874-24-8
IUPAC name
3-hydroxypyridine-2-carboxylic acid
State
State

At room temperature, 3-hydroxypyridine-2-carboxylic acid is a solid.

Melting point (Celsius)
206.00
Melting point (Kelvin)
479.15
Boiling point (Celsius)
357.00
Boiling point (Kelvin)
630.15
General information
Molecular weight
139.11g/mol
Molar mass
139.1120g/mol
Density
1.5950g/cm3
Appearence

3-Hydroxypyridine-2-carboxylic acid appears as a solid crystalline powder. It is typically white to light yellow in color.

Comment on solubility

Solubility of 3-hydroxypyridine-2-carboxylic acid

3-hydroxypyridine-2-carboxylic acid, also known as pyridoxine acid, exhibits notable solubility characteristics that are essential for its applications in various chemical processes. Understanding its solubility behavior can be summarized as follows:

  • Solvent Preferences: This compound is typically soluble in polar solvents such as water and ethanol, which makes it versatile for medicinal and biochemical uses.
  • pH Influence: The solubility of 3-hydroxypyridine-2-carboxylic acid is significantly affected by the pH of the solution. In more acidic conditions, its solubility can increase due to the protonation of the carboxylic acid group.
  • Temperature Effects: Like many organic acids, solubility generally increases with temperature; therefore, heating the solvent can enhance dissolution rates.
  • Cation Effects: The presence of cations may also influence solubility, as certain metal ions can form soluble complexes with the compound.

In summary, the solubility of 3-hydroxypyridine-2-carboxylic acid is generally favorable in specific conditions, making it a useful compound in both laboratory and industrial applications.

Interesting facts

Interesting Facts About 3-Hydroxypyridine-2-Carboxylic Acid

3-Hydroxypyridine-2-carboxylic acid, commonly known as α-hydroxypicolinic acid, is a fascinating compound within the realm of organic chemistry. This compound holds several remarkable properties and applications that make it noteworthy for both researchers and industry professionals alike. Here are some interesting aspects:

  • Biological Significance: This compound plays a role in various biological processes. It has been studied for its potential antibacterial and antifungal properties, making it a subject of interest in medicinal chemistry.
  • Metal Complexation: 3-hydroxypyridine-2-carboxylic acid is known for its ability to form stable complexes with transition metals. This feature is particularly useful in analytical chemistry for the extraction and determination of metal ions.
  • Organic Synthesis: This compound is a vital precursor in the synthesis of various pharmacologically active compounds, making it significant in drug discovery and development.
  • Role in Agriculture: Its derivatives have been explored in agricultural applications, particularly as growth regulators, which can enhance crop yields.
  • Research Tool: Researchers utilize it as a building block in synthetic pathways due to its versatility and reactivity, contributing to the development of new materials and chemicals.

Quote from Science: “The exploration of new compounds leads not only to advancements in science but also opens doors to future innovations that can change the world.”

In conclusion, 3-hydroxypyridine-2-carboxylic acid exemplifies the intricate relationship between chemistry and practical applications, showcasing its importance through diverse fields, including medicine, agriculture, and synthetic chemistry. Its multifaceted nature continues to intrigue scientists and stimulate further research.

Synonyms
3-HYDROXYPICOLINIC ACID
874-24-8
3-Hydroxypyridine-2-carboxylic acid
3-Hydroxy-2-pyridinecarboxylic acid
2-Pyridinecarboxylic acid, 3-hydroxy-
CHEBI:64342
XV7XP64JR5
EINECS 212-859-0
DTXSID80236320
DTXCID80158811
212-859-0
3-HPA
MFCD00006294
Pyridinecarboxylic acid, hydroxy-
116357-04-1
CHEMBL1234326
3-hydroxy-2-pyridine carboxylic acid
3-Hydroxypicolinicacid
3-Hydroxypicolinate
3-Hydroxypicolinic acid, matrix substance for MALDI-MS
hydroxypicolinic acid
3-hydroxylpicolinic acid
3-hydroxy picolinic acid
3-Hydroxy-picolinic acid
UNII-XV7XP64JR5
NCIOpen2_001249
SCHEMBL78249
3-Hydroxy-2-pyridinecarboxylate
3-hydroxypyridine-2-carboxylate
HY-Y0030A
3-Hydroxypyridinium-2-carboxylate
CS-D1114
HY-Y0030
BBL100164
BDBM50122011
STL227625
AKOS005170696
3-Hydroxy-2-pyridinecarboxylic acid #
FH06201
PB46989
PS-3718
AC-26465
BP-12461
PD069985
SY017848
3-Hydroxypyridine-2-carboxylic acid, 98%
DB-016012
CS-0899663
H0787
NS00014723
S6252
EN300-51029
C18620
3-Hydroxypicolinic acid, purum, >=96.0% (T)
AC-907/25014108
AF-399/40173370
Q10859486
Z608353738
3-Hydroxypicolinic acid (3-Hydroxypyridine-2-carboxylic acid)
3-Hydroxypicolinic acid, matrix substance for MALDI-MS, >=99.0% (HPLC)
MHW