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3-Iodo-5-nitroaniline

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Identification
Molecular formula
C6H5IN2O2
CAS number
609-72-3
IUPAC name
3-iodo-5-nitro-aniline
State
State

At room temperature, 3-iodo-5-nitroaniline is a solid. Its solid state makes it suitable for use in various chemical synthesis applications where it is typically handled as a solid powder or crystalline form.

Melting point (Celsius)
173.00
Melting point (Kelvin)
446.15
Boiling point (Celsius)
321.00
Boiling point (Kelvin)
594.15
General information
Molecular weight
264.01g/mol
Molar mass
264.0130g/mol
Density
1.9600g/cm3
Appearence

3-Iodo-5-nitroaniline is typically a yellow to light-brown crystalline solid. The compound has a distinct crystalline form that is often described as needle-like or flaky, depending on the crystallization conditions.

Comment on solubility

Solubility of 3-iodo-5-nitro-aniline

3-iodo-5-nitro-aniline is a chemical compound that exhibits notable solubility characteristics. Understanding its solubility can provide valuable insights into its behavior in various solvents and applications. Here are some pertinent points regarding its solubility:

  • Polar Solvents: This compound is likely to have enhanced solubility in polar protic solvents such as water and alcohols due to the presence of the aniline group, which can engage in hydrogen bonding.
  • Non-Polar Solvents: Conversely, it may exhibit limited solubility in non-polar solvents due to its increased molecular weight and presence of nitro and iodo groups, which do not favor hydrophobic interactions.
  • Thermal Sensitivity: Additionally, the solubility can be impacted by temperature; generally, increasing the temperature will enhance solubility for many compounds due to the increased kinetic energy of molecules.

As a rule of thumb, compounds with functional groups capable of facilitating interactions with solvents tend to show better solubility. The presence of the nitro and iodo groups may also introduce complexities, affecting the overall solubility profile.

In conclusion, the solubility of 3-iodo-5-nitro-aniline is a nuanced topic, influenced by both polarity and temperature; a careful examination in experimental conditions is often required to determine its precise solubility behavior.

Interesting facts

Exploring 3-Iodo-5-Nitro-Aniline

3-Iodo-5-nitro-aniline, a fascinating organic compound, belongs to the family of nitroanilines and is characterized by intriguing properties and applications. Here are some interesting facts about this compound:

  • Structure and Functionality: The compound contains both an iodine atom and a nitro group (-NO2) attached to an aniline ring, creating a molecule with unique reactivity, making it an interesting target for synthetic organic chemistry.
  • Applications in Dye Chemistry: Due to its vibrant color properties, 3-iodo-5-nitro-aniline is often utilized in the manufacturing of dyes, which are widely used in textiles, paper, and plastics.
  • Importance in Pharmaceuticals: The nitroaniline derivatives are an important class of compounds in medicinal chemistry. They serve as precursors in the synthesis of a variety of pharmaceuticals, including potential anti-cancer and anti-inflammatory drugs.
  • Research in Analytical Chemistry: This compound is frequently employed in chromatographic techniques, enabling scientists to analyze mixtures effectively, adding to the field's continued advancement.
  • Toxicity and Safety: Like many nitro compounds, 3-iodo-5-nitro-aniline is handled with caution in laboratories due to its potential toxicity; understanding proper handling protocols is crucial for safety during experimentation.

In essence, 3-iodo-5-nitro-aniline serves as a bridge between theoretical and practical applications in both industrial and research settings. Its unique structure facilitates a wide range of applications, making it an important compound in a chemist's toolkit.

As emphasized by chemists worldwide: "Innovation in chemistry often lies within the unique structures of molecules that challenge our understanding."

Synonyms
3-Iodo-5-nitroaniline
631-272-4
10394-64-6
Benzenamine, 3-iodo-5-nitro-
ANILINE, 3-IODO-5-NITRO-
NSC 88993
BRN 1944986
NSC88993
WLN: ZR CI ENW
aniline, 5-iodo-3-nitro-
NCIOpen2_005650
SCHEMBL6651088
DTXSID20146151
BKYNSFHBQVINES-UHFFFAOYSA-N
NSC-88993
AKOS015916483
EN300-1272900