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3-Iodobenzoic acid

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Identification
Molecular formula
C7H5IO2
CAS number
618-51-9
IUPAC name
3-iodobenzoic acid
State
State

At room temperature, 3-iodobenzoic acid exists as a solid. Its crystalline nature makes it well-suited for storage in a dry, stable environment away from light and moisture.

Melting point (Celsius)
163.00
Melting point (Kelvin)
436.15
Boiling point (Celsius)
326.00
Boiling point (Kelvin)
599.15
General information
Molecular weight
248.02g/mol
Molar mass
248.0220g/mol
Density
2.3230g/cm3
Appearence

3-Iodobenzoic acid typically appears as a white to off-white crystalline solid. It is usually found in a powdered form but can also appear as large crystals depending on the method of preparation and purification.

Comment on solubility

Solubility of 3-Iodobenzoic Acid

3-Iodobenzoic acid, with the chemical formula C7H5IO2, is known for its specific solubility characteristics. Understanding the solubility of this compound is key in various applications, particularly in pharmaceuticals and chemical synthesis. Here are some important points to consider about its solubility:

  • Solvent Properties: 3-Iodobenzoic acid is primarily soluble in organic solvents such as ethanol, acetone, and dichloromethane, demonstrating moderate solubility in these environments.
  • Water Solubility: It has limited solubility in water due to the presence of the hydrophobic −I (iodine) substituent, which hinders interactions with polar water molecules.
  • Temperature Effects: The solubility of 3-iodobenzoic acid may increase with rising temperatures, which is common for many organic acids.
  • pH Influence: The acidic nature of this compound implies that its solubility in water could increase in alkaline conditions due to its ionization, thus forming a more soluble anionic species.

In summary, while 3-iodobenzoic acid is sparingly soluble in water, it exhibits better solubility in a variety of organic solvents. Understanding these solubility dynamics is essential for effective use in chemical processes.

Interesting facts

Interesting Facts about 3-Iodobenzoic Acid

3-Iodobenzoic acid is a fascinating compound that belongs to the class of aromatic carboxylic acids. Here are some notable aspects that highlight its significance in various fields:

  • Synthetic Intermediates: This compound serves as a critical intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its unique structure allows for functionalization that can enhance desired properties in related compounds.
  • Substitutive Influence: The iodine atom's presence in the meta position significantly affects the compound’s reactivity and the electronic distribution in the aromatic ring, making it a valuable subject of study in organic chemistry.
  • Research Applications: 3-Iodobenzoic acid is often used in studies relating to drug synthesis, showcasing its ability to affect biological pathways through the introduction of iodine, which can serve as a radiolabel in imaging techniques.
  • Polar vs Nonpolar: The compound's properties can vary based on its functional groups, providing a rich ground for research in solubility and interactions with other organic solvents.
  • History of Use: The discovery and application of 3-iodobenzoic acid reflect broader developments in organic synthesis, marking its role in the evolution of chemical methodologies throughout the years.

As echoed by chemists worldwide, "Every compound tells a story," and 3-iodobenzoic acid is no exception. Its structural and functional nuances continue to inspire new research and applications, proving that a deeper understanding of even seemingly simple compounds can yield exciting scientific advancements.

In conclusion, whether it’s its role in organic synthesis, its unique reactivity due to iodine substitution, or its applicability in research settings, 3-iodobenzoic acid remains a compound of immense interest!

Synonyms
3-IODOBENZOIC ACID
618-51-9
Benzoic acid, 3-iodo-
m-Iodobenzoic acid
Benzoic acid, m-iodo-
Q4ZCP9G95X
EINECS 210-555-2
NSC 74693
NSC-74693
M-CARBOXYIODOBENZENE
DTXSID6060682
CHEBI:166852
BENZOIC ACID, 3-(IODOCARBONYL)-
m-iodobenzoate
Benzoic acid, m-iodo-(8CI)
DTXCID0043133
210-555-2
inchi=1/c7h5io2/c8-6-3-1-2-5(4-6)7(9)10/h1-4h,(h,9,10
3-Iodo-benzoic acid
MFCD00002496
3-Iodobenzenecarboxylic Acid; NSC 176131; NSC 74693; m-Carboxyiodobenzene; m-Iodobenzoic Acid;
3-Iodo benzoic acid
meta-carboxy iodo-benzene
UNII-Q4ZCP9G95X
3-Iodobenzoic acid, 98%
META-IODOBENZOIC ACID
NCIOpen2_003856
SCHEMBL40282
CHEMBL67526
HMS1783G17
HY-Y0931
NSC74693
STR07725
STK286092
AKOS000119736
CS-W009273
FI37249
PS-7510
SB66453
NCGC00341575-01
AC-22932
PD210650
SY001406
DB-014298
I0052
NS00034816
EN300-17391
3-Iodobenzoic acid, purum, >=98.0% (HPLC)
AB01333667-02
AE-562/43403710
Q18472702
Z56924537
F2191-0117