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Carvedilol

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Identification
Molecular formula
C24H26N2O4
CAS number
72956-09-3
IUPAC name
3-(isopropylamino)-1-(7-methylindan-4-yl)oxy-butan-2-ol
State
State

At room temperature, carvedilol is in the solid state, appearing as a white to off-white crystalline powder.

Melting point (Celsius)
114.00
Melting point (Kelvin)
387.15
Boiling point (Celsius)
294.00
Boiling point (Kelvin)
567.15
General information
Molecular weight
406.49g/mol
Molar mass
406.4850g/mol
Density
1.1390g/cm3
Appearence

Carvedilol is a white to off-white crystalline powder, practically insoluble in water but soluble in dimethyl sulfoxide and methanol. It is noted for its lack of strong coloration.

Comment on solubility

Solubility of 3-(isopropylamino)-1-(7-methylindan-4-yl)oxy-butan-2-ol (C24H26N2O4)

The solubility of the compound 3-(isopropylamino)-1-(7-methylindan-4-yl)oxy-butan-2-ol can be quite intriguing due to its unique molecular structure. Solubility is governed by various factors including polarity, molecular interactions, and the presence of functional groups. Here are some insights into its solubility characteristics:

  • Polarity: The compound contains both hydrophilic (amine and alcohol groups) and hydrophobic (aromatic structure) regions, which may result in variable solubility in different solvents.
  • Solvent Compatibility: It may exhibit higher solubility in polar solvents like water or methanol compared to non-polar solvents due to its polar functionalities.
  • Temperature Influence: The solubility is likely to increase with temperature, following the general trend for organic compounds.
  • Intermolecular Interactions: Hydrogen bonding from the hydroxy (-OH) and amine (-NH) groups can enhance solubility in polar environments.

In summary, while the hydrophilic portions of this compound contribute to its potential solubility in polar solvents, the presence of hydrophobic regions suggests that solubility behavior may vary based on the solvent system used. Understanding these interactions can provide critical insights into effective applications and formulations involving this compound.

Interesting facts

3-(Isopropylamino)-1-(7-methylindan-4-yl)oxy-butan-2-ol

This intriguing compound, known for its complex structure and potential biological applications, is an example of a morpholine derivative that has garnered interest in medicinal chemistry. Here are some fascinating points about it:

  • Structural Diversity: The compound contains a unique combination of an isopropylamino group and a methylindan moiety, showcasing the versatility of organic synthesis.
  • Potential Pharmacological Effects: Compounds with similar structures have been investigated for their activity in modulating neurotransmitter systems, possibly impacting mood and cognitive functions.
  • Research Applications: Given its novel chemical framework, this compound may serve as a lead compound in the design of new therapeutic agents targeting neurological disorders.
  • Importance of Stereochemistry: The chiral centers present in the compound play a significant role in determining its biological activity, highlighting the necessity for careful consideration in drug development.

In summary, 3-(isopropylamino)-1-(7-methylindan-4-yl)oxy-butan-2-ol exemplifies the fascinating intersection of organic chemistry and pharmacology. With ongoing research, this compound may open new avenues in therapeutic strategies, emphasizing the dynamic nature of chemical compounds in health science.

Synonyms
ICI-118,551
ICI 118,551
1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-(propan-2-ylamino)butan-2-ol
72795-19-8
72795-26-7
Ici 118551
ICI-118551
3-(Isopropylamino)-1-((7-methyl-2,3-dihydro-1H-inden-4-yl)oxy)butan-2-ol
91021-57-7
Lopac0_000714
ICI 118551;ICI-118551;ICI118551
SCHEMBL146178
CHEMBL513389
BDBM25768
CHEBI:91879
DTXSID70874977
VFIDUCMKNJIJTO-UHFFFAOYSA-N
72795-20-1
XCA79519
CCG-204799
NCGC00015535-03
NCGC00015535-04
NCGC00024805-02
NCGC00024805-03
L000304
Q6571514
BRD-A78942461-003-01-3
(+/-)-1-[2,3-(dihydro-7-methyl-1h-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol
1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-(propan-2-ylamino)-2-butanol
1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-[(propan-2-yl)amino]butan-2-ol