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3-Methoxy-4-methyl-aniline

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Identification
Molecular formula
C8H11NO
CAS number
531-55-5
IUPAC name
3-methoxy-4-methyl-aniline
State
State

At room temperature, 3-Methoxy-4-methyl-aniline is in the liquid state. It may solidify just above room temperature, depending upon ambient conditions, due to its relatively high melting point.

Melting point (Celsius)
6.00
Melting point (Kelvin)
279.15
Boiling point (Celsius)
244.00
Boiling point (Kelvin)
517.15
General information
Molecular weight
137.18g/mol
Molar mass
137.1820g/mol
Density
1.0290g/cm3
Appearence

3-Methoxy-4-methyl-aniline is typically a colorless to pale yellow liquid. Over time and upon exposure to air, it may darken due to oxidation.

Comment on solubility

Solubility of 3-methoxy-4-methyl-aniline

3-methoxy-4-methyl-aniline, a member of the aniline family, exhibits unique solubility characteristics due to its molecular structure. Here are some key points about its solubility:

  • Polar Nature: The presence of the methoxy group (-OCH3) enhances the polarity of the molecule, which generally increases its solubility in polar solvents such as water.
  • Hydrophobic Component: However, the methyl group attached to the aromatic ring contributes to hydrophobic interactions, which may reduce its overall solubility in water.
  • Organic Solvents: This compound is typically more soluble in organic solvents like ethanol, methanol, and acetone, where it can interact favorably.
  • pH Effect: The solubility of 3-methoxy-4-methyl-aniline may also be affected by the pH of the solution. Under acidic conditions, protonation can enhance solubility in aqueous solutions.

In summary, while 3-methoxy-4-methyl-aniline shows some solubility in water due to its polar methoxy group, it tends to have better solubility in organic solvents, making it versatile in various chemical applications. Understanding these solubility dynamics is crucial for its effective use in synthesis and formulation.

Interesting facts

Interesting Facts about 3-Methoxy-4-Methyl-Aniline

3-Methoxy-4-methyl-aniline, also known as p-cresol-anisidine, is an intriguing compound with diverse applications in the field of chemistry and industry. Below are some fascinating aspects of this chemical:

  • Structure and Functionality: The compound consists of an aniline derivative, featuring both a methoxy group (–OCH3) and a methyl group (–CH3). This combination of groups influences its reactivity and property profile, making it important in various chemical reactions.
  • Use in Dyes: One of the prominent applications of 3-methoxy-4-methyl-aniline is as an intermediate in the synthesis of dyes and pigments. These colors are widely used in textiles and inks, showcasing the compound's role in industries that require vibrant and stable colorants.
  • Pharmaceutical Precursors: The compound serves as a precursor for numerous pharmaceuticals, contributing to the development of medications. Its ability to serve as a building block underscores its significance in medicinal chemistry.

When discussing chemical compounds, it's fascinating how small structural changes can lead to significant differences in functionality. For example, the positioning of the methoxy and methyl groups in 3-methoxy-4-methyl-aniline are crucial for its reactivity and applications. As a reminder, the study of such compounds encourages scientists to explore novel synthetic pathways and applications.

In summary, 3-methoxy-4-methyl-aniline showcases the intricate relationship between molecular structure and practical applications, making it a compound of interest for both students and seasoned chemists alike.

Synonyms
3-Methoxy-4-methylaniline
O-CRESIDINE
Benzenamine, 3-methoxy-4-methyl-
CCRIS 4606
UNII-V82SCC5X3Q
EINECS 240-500-8
V82SCC5X3Q
4-METHYL-M-ANISIDINE
BRN 0742602
(3-METHOXY-4-METHYLPHENYL)AMINE
DTXSID9024855
4-AMINO-2-METHOXYTOLUENE
CRESIDINE, O-
4-methyl-3-methoxyaniline
DTXCID504855
M-ANISIDINE, 4-METHYL-
4-13-00-01666 (Beilstein Handbook Reference)
3-METHOXY-P-TOLUIDINE
4-AMINO-6-METHOXYTOLUENE
240-500-8
InChI=1/C8H11NO/c1-6-3-4-7(9)5-8(6)10-2/h3-5H,9H2,1-2H
ONADZNBSLRAJFW-UHFFFAOYSA-N
16452-01-0
3-Methoxy-4-methyl aniline
MFCD00025371
3-methoxy-4-methyl-aniline
3-methoxy-4-methylphenylamine
2-Methoxy-4-aminotoluene
5-amino-2-methylanisole
SCHEMBL264325
3-methoxy-4-methyl-phenylamine
4-methyl-3-(methyloxy)aniline
SCHEMBL3250672
SCHEMBL8384885
CHEMBL3188424
3-Methoxy-4-methylaniline, 98%
Tox21_202884
BBL104205
CL8431
SBB085977
STL558039
AKOS002320303
AS-0004
CS-W007666
FA67760
NCGC00260430-01
SY007315
CAS-16452-01-0
DB-043593
NS00025379
ST50758930
EN300-84943
Q27291652