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3-Anisidine

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Identification
Molecular formula
C13H13NO
CAS number
536-90-3
IUPAC name
3-methoxy-N-phenyl-aniline
State
State
Liquid at room temperature. Typically stored under inert gas to prevent oxidation.
Melting point (Celsius)
6.00
Melting point (Kelvin)
279.15
Boiling point (Celsius)
263.00
Boiling point (Kelvin)
536.15
General information
Molecular weight
199.25g/mol
Molar mass
199.2510g/mol
Density
1.1340g/cm3
Appearence

3-Anisidine is typically a colorless to light yellow liquid. When exposed to air, it may darken due to oxidation. Proper storage and handling are required to maintain its color integrity.

Comment on solubility

Solubility of 3-methoxy-N-phenyl-aniline

3-methoxy-N-phenyl-aniline, known for its distinctive structure and properties, exhibits interesting solubility characteristics. This compound tends to be soluble in a variety of organic solvents due to the presence of the methoxy group, which enhances its polarity. However, its solubility in water is significantly limited. Let's explore the solubility in detail:

Key Points of Solubility:

  • Organic Solvents: The compound is soluble in many organic solvents such as ethanol, acetone, and chloroform, making it suitable for various applications in organic synthesis.
  • Water Solubility: 3-methoxy-N-phenyl-aniline shows low solubility in water, attributed to its bulky phenyl group which hinders interactions with polar water molecules.
  • Temperature Effects: Generally, increasing temperature can improve the solubility of this compound in organic solvents, but it does not markedly affect its low water solubility.
  • pH Influence: The solubility may vary with pH changes, particularly due to potential protonation of the amino group under acidic conditions, altering its overall solubility profile.

In summary, while 3-methoxy-N-phenyl-aniline demonstrates favorable solubility in organic media, its low water solubility limits its utility in aqueous environments. As a rule of thumb, remember: “Like dissolves like”, so this compound fits well within non-polar or weakly polar solvents.

Interesting facts

Interesting Facts about 3-Methoxy-N-phenyl-aniline

3-Methoxy-N-phenyl-aniline, a fascinating organic compound, belongs to the class of anilines which are aromatic amines. This compound features a distinct structure due to its methoxy group and phenyl group, contributing to its unique chemical properties.

Key Characteristics:

  • Versatile Applications: 3-methoxy-N-phenyl-aniline is often used in the synthesis of dyes, pharmaceuticals, and agrochemicals.
  • Functional Group Interactions: The presence of the methoxy group enhances its reactivity through electrophilic substitution, making it a valuable intermediate in organic synthesis.
  • Biological Importance: Compounds similar to 3-methoxy-N-phenyl-aniline have been investigated for their potential biological activities, including anti-cancer and anti-inflammatory properties.

Furthermore, the aniline structure allows for the formation of various derivatives through substitutive reactions, fostering innovation in medicinal chemistry. As a chemist, it’s intriguing to explore how such small structural changes can result in significantly different properties and functions.

Quote to Ponder:

"The beauty of chemistry lies in its ability to transform simple molecules into intricate compounds, each with its own story to tell."

In summary, 3-methoxy-N-phenyl-aniline serves as an excellent example of how compounds can interplay between structure and function, paving the way for new discoveries in the chemical sciences.

Synonyms
3-Methoxydiphenylamine
101-16-6
3-methoxy-n-phenylaniline
Benzenamine, 3-methoxy-N-phenyl-
N-Phenyl-m-anisidine
EINECS 202-921-5
MFCD00008383
DTXSID10143614
N-phenyl-3-methoxyaniline
3-methoxy diphenylamine
N1-phenyl-3-methoxyaniline
N-(3-Methoxyphenyl)-N-phenylamine
3-methoxydiphenylamin
3-Methoxydiphenylamine, 98%
BIDD:GT0233
SCHEMBL917608
DTXCID6066105
MKASXAGBWHIGCF-UHFFFAOYSA-
n(3-methoxyphenyl)-n-phenylamine
STR04774
3-METHOXY-N-PHENYLBENZENAMINE
AKOS000121435
N-(3-Methoxyphenyl)-N-phenylamine #
CS-W010505
AC-22498
M1135
NS00023033
EN300-21118
N-(3-Methoxyphenyl)-N-phenylamine;3-methoxy-N-phenylaniline
202-921-5
InChI=1/C13H13NO/c1-15-13-9-5-8-12(10-13)14-11-6-3-2-4-7-11/h2-10,14H,1H3